Acta Veterinaria et Zootechnica Sinica ›› 2023, Vol. 54 ›› Issue (2): 473-483.doi: 10.11843/j.issn.0366-6964.2023.02.006

• REVIEW • Previous Articles     Next Articles

Advances in the Roles of Curcumin on Regulating Gut Microbiota and Antiviral Effects

ZHUO Ruhao1, LIU Qingyang2, ZHONG Xiang1*   

  1. 1. College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China;
    2. College of Life Science, Nanjing Agricultural University, Nanjing 210095, China
  • Received:2022-04-11 Online:2023-02-23 Published:2023-02-21

Abstract: As a natural polyphenolic plant extract, curcumin has many biological activities such as anti-inflammatory, anti-oxidant, anti-stress and improving animal intestinal health, and has become a green, safe and efficient feed additive. In recent years, studies have shown that curcumin has a close interaction with the gut microbiota. Curcumin can regulate the composition and diversity of the gut microbiota, and the gut microbiota affects the conversion of curcumin. This two-way regulation may be very important to the physiological function of curcumin. In addition, curcumin has been confirmed to resist multiple viral infections through different mechanisms, suggesting that it has the potential to become a new type of antiviral drug. Therefore, this article mainly reviews the interaction between curcumin and the gut microbiota and the related mechanisms of curcumin against different viral infections, with the final aim of providing theoretical basis for further understanding the mechanism of curcumin on improving animal health, and developing novel environment-friendly feed additive.

Key words: curcumin, gut microbiota, regulatory effects, antiviral effects

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