北京地区犬呼吸道冠状病毒感染状况的监测与分析

doi:10.11843/j.issn.0366-6964.2022.10.024

Abstract

Abstract: This study aimed to analyse the pathogenic characteristics and the epidemiological situation of canine respiratory coronavirus (CRCoV) in Beijing. From December 2015 to March 2017, Pharynx nasal swabs from 487 dogs were collected and reverse transcriptional polymerase chain reactions was used to detect CRCoV. Meanwhile, some of the samples were also used to detected canine parainfluenza virus (CPIV), canine adenovirus type 2 (CAV-2) and canine distemper virus (CDV) for exploring the situation of mixed infection. The results showed that:1) The positive rates of CRCoV was 21.36% (104/487). The mixed infection rates of CRCoV and CPIV, CAV-2, CDV were 3.43% (11/321), 0% (0/156) and 3.85% (6/156) respectively. 2) Among all 455 cases which had respiratory symptom records, dogs which had non-respiratory symptom accounting for 27.19% of all dogs without respiratory symptoms, dogs which had mild respiratory symptoms (coughing and nasal discharging) accounting for 19.73% of all dogs with mild respiratory symptoms, dogs which had moderate to severe respiratory symptoms (pneumonia) accounting for 14.28% of all dogs with moderate to severe respiratory symptoms. 3) From November 2016 to March 2017, the mixed infection between CRCoV and CPIV, CAV-2, CDV in 146 cases was explored. The mixed infection rates of the dogs which were tested CRCoV positive and had non-respiratory symptom was 12.50%. The mixed infection rates of the dogs which were tested CRCoV positive and had mild respiratory symptoms was 41.18%. The mixed infection rates of the dogs which were tested CRCoV positive and had moderate to severe respiratory symptoms was 100.00%. 4) The infection rates of CRCoV varied from 15.56% to 22.97% in different age groups among 454 samples. Except for the high positive rates in July, the positive rates in cold season is higher than warm season. These results indicated that the pathogenicity of CRCoV is rather weak. Dogs suffer pure infection of this virus often show non-respiratory symptom or mild respiratory symptoms. Dogs which are CRCoV positive suffer mixed infection often show mild respiratory symptoms or moderate to severe respiratory symptoms. This virus is more likely to be prevalent in winter and spring. The infection rates has no significant relationship with age.

Key words: canine respiratory coronavirus, infective rates, pathogenic characteristics, epidemiology

CLC Number:

S852.659.6

XIAO Yuan, LÜ Yanli, SUN Yanzheng. Surveillance and Analysis of Canine Respiratory Coronavirus Infection in Beijing[J]. Acta Veterinaria et Zootechnica Sinica, 2022, 53(10): 3522-3529.

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Surveillance and Analysis of Canine Respiratory Coronavirus Infection in Beijing

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