Acta Veterinaria et Zootechnica Sinica ›› 2023, Vol. 54 ›› Issue (3): 900-913.doi: 10.11843/j.issn.0366-6964.2023.03.005

• REVIEW • Previous Articles     Next Articles

Research Advances in Kobuvirus

ABI-kehamo1, TANG Cheng1,2, YANG Chen1, YANG Falong1,2*   

  1. 1. Department of Veterinary Medicine, College of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu 610041, China;
    2. Key Laboratory of Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization, Chengdu 610041, China
  • Received:2022-07-21 Online:2023-03-23 Published:2023-03-21

Abstract: Kobuvirus (KoV) is a single-stranded, positive-sense RNA virus in a new genus of the picornavirus family and currently includes 6 species of Aichivirus A-F. KoV can infect humans and animals through direct or indirect contact. The main clinical symptom of infected animals is diarrhea. The virus is widely distributed all over the world. To date, KoV has been detected in 17 countries including the USA, China, Japan, Pakistan, Brazil, Germany, France, Tunisia, etc., suggesting that KoV has been widely distributed around the world. Recently, our studies suggested that the virus has been widely circulating among goats and sheep in China, presenting a unique evolution trend, and new genotypes have been determined. To provide a reference for KoV research, this review describes the latest research progress on KoV, including the genome structure and its coding protein, epidemiology, biological characteristics, pathogenesis and detection methods.

Key words: kobuvirus, etiology, diarrhea, epidemiology, detection technology

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