环状RNA的生物学功能及其在家禽中的研究进展

doi:10.11843/j.issn.0366-6964.2021.07.002

Abstract

Abstract: With the development of high-throughput sequencing and bioinformatics in recent years, as a newcomer, circular RNA (circRNA) has attracted much attention in the field of biology. circRNAs are endogenous non-coding RNAs (ncRNAs) that usually derived from back-splicing of pre-mRNA to form a covalent closed loop. circRNA has no freely expressed 3' and 5' ends in eukaryotic cells, this special structure makes it highly insensitive to exonucleases. This article reviews the brief research history, type, alternative splicing, biological function of circRNA and its latest research progress in poultry to provide new perspectives for genetic improvement of poultry.

Key words: circular RNA, alternative splicing, biological function, poultry

CLC Number:

S813.2

WANG Weizhen, DENG Zhanzhao, XIN Guosheng, CAI Zhengyun, GU Yaling, ZHANG Juan. The Biological Function of Circular RNA and Its Research Progress in Poultry[J]. Acta Veterinaria et Zootechnica Sinica, 2021, 52(7): 1778-1788.

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The Biological Function of Circular RNA and Its Research Progress in Poultry

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