Acta Veterinaria et Zootechnica Sinica ›› 2020, Vol. 51 ›› Issue (1): 9-17.doi: 10.11843/j.issn.0366-6964.2020.01.002

• REVIEW • Previous Articles     Next Articles

Research Progress on Biological Mechanisms Related to Wool Bending and Hair Follicle Development

DING Yangyang1, LIU Zhanfa2, MENG Xiangren3, MA Yuehui1, PU Yabin1, ZHAO Qianjun1*   

  1. 1. Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China;
    2. Ningxia Hui Autonomous Region Zhongwei Goat Farm, Ningxia 755000, China;
    3. Institute of Animal Science, Heilongjiang Academy of Agricultural Sciences, Harbin 150086, China
  • Received:2019-06-18 Online:2020-01-23 Published:2020-01-17

Abstract: Wool curvature is one of the key factors affecting wool quality. The decrease of wool curvature and the change of wool strand from compactness to fluffy will lead to the decline of wool quality, which will affect the value of fur. Hair follicle is a skin accessory organ that regulates hair growth and plays an important role in the formation of curvature of hair. In recent years, some progress had been made in the study of curvature formation of hair fibers in sheep, mice and other animals, as well as in the regulation of hair follicle development. In this paper, the characteristics of wool fiber structure were introduced, and the important regulatory signaling pathways related to hair follicle development and their effects on hair curvature were elaborated. In summary, the research progress of wool curvature related genes and proteins were reviewed. The biological mechanism of wool curvature and hair follicle development were summarized in order to provide theoretical basis for the study of molecular mechanism of wool curvature and hair follicle development, and to provide some references for improving wool curvature characteristics.

Key words: wool curvature, hair follicle development, protein, mechanism

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