寄生虫来源的外泌体研究进展

doi:10.11843/j.issn.0366-6964.2019.05.002

Abstract

Abstract:

Exosomes are vesicles secreted by various cells, containing proteins, lipids and nucleic acids, and have effects in signal transduction, immune regulation, metabolite management and coagulation. Exosomes are important media in information transfer between parasites and hosts. Parasites can transfer biological active substances into host cells, regulate immune responses by secreting exosomes. Exosomes can serve as drug carriers to block the transfer of parasites into host cells and enhance the immunity of host, so they provide a new opportunity for the prevention and treatment of parasitic diseases, break the frequent use of chemical synthetic drugs in livestock production, reduce drug residues, improve the quality and safety of animal products. This article reviews the formation, composition and the effects of exosomes derived from different parasites, in order to lay the foundation for the diagnosis and treatment of parasitic diseases.

CLC Number:

S855.9

NI Aixin, MA Hui, CHEN Jilan. Research Progress of Parasite-derived Exosomes[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2019, 50(5): 909-917.

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Research Progress of Parasite-derived Exosomes

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