代谢组学应用于猪重要经济性状遗传解析

doi:10.11843/j.issn.0366-6964.2025.10.003

畜牧兽医学报 ›› 2025, Vol. 56 ›› Issue (10): 4787-4795.doi: 10.11843/j.issn.0366-6964.2025.10.003

代谢组学应用于猪重要经济性状遗传解析

高志苗¹^,²(), 倪海花³, 王彦平¹, 赵雪艳¹, 李菁璇¹, 王继英¹^,*(), 张勤²^,*()

1. 山东省农业科学院畜牧兽医研究所, 农业农村部畜禽生物组学重点实验室, 济南 250100
2. 山东农业大学动物科技学院, 泰安 271018
3. 西北农林科技大学动物科技学院, 杨凌 712100

收稿日期:2025-02-17 出版日期:2025-10-23 发布日期:2025-11-01
通讯作者: 王继英,张勤 E-mail:gzm230906@126.com;jnwangjiying@163.com;qzhang@sdau.edu.cn
作者简介:高志苗(1995-)，女，蒙古族，河北张家口人，硕士生，主要从事猪遗传育种研究，E-mail: gzm230906@126.com
基金资助:
山东省重点研发计划(2022LZGC003)；山东省生猪产业技术体系(SDAIT-08-03)；山东省牧草产业技术体系(SDAIT-23-07)

Application of Metabolomics in Genetic Analysis of Important Economic Traits in Pigs

GAO Zhimiao¹^,²(), NI Haihua³, WANG Yanping¹, ZHAO Xueyan¹, LI Jingxuan¹, WANG Jiying¹^,*(), ZHANG Qin²^,*()

1. Key Laboratory of Livestock and Poultry Multi-omics of Ministry of Agriculture and Rural Affairs, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan 250100, China
2. College of Animal Science and Technology, Shandong Agricultural University, Tai'an 271018, China
3. College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China

Received:2025-02-17 Online:2025-10-23 Published:2025-11-01
Contact: WANG Jiying, ZHANG Qin E-mail:gzm230906@126.com;jnwangjiying@163.com;qzhang@sdau.edu.cn

摘要/Abstract

摘要：

随着组学技术的飞速发展，各层次组学的高通量检测技术不断涌现。代谢组学作为20世纪后期兴起的一个新近研究领域，不仅可以对生物体内的所有代谢物进行识别与检测，还可以借助先进的分析技术与数据处理平台对收集到的代谢物信息进行深入、全面的解析。它不仅可以全面、动态地监测猪生长发育过程中体内的代谢变化，而且还可结合多组学数据联合分析为经济性状的机理解析提供新方法。本文主要概述了代谢组学在猪生长、肉质、繁殖、抗病等重要经济性状研究中的最新进展，探讨其面临的挑战和应用前景，为未来代谢组学在猪重要经济性状研究中的应用提供参考。

关键词: 代谢组学, 代谢物, 猪, 经济性状

Abstract:

With the rapid development of omics technology, high-throughput detection technologies of omics at all levels are emerging. As a new research field rising in the late 20th century, metabolomics can not only identify and detect all metabolites in organisms, but also use advanced analysis technology and data processing platform to analyze the collected metabolite information in depth and comprehensively. It can not only comprehensively and dynamically monitor the metabolic changes in pigs during growth and development, but also provide a new method for the mechanism analysis of economic traits by combining multi-omics data. This paper mainly summarizes the latest progress of metabolomics in the study of important economic traits such as pig growth, meat quality, reproduction and disease resistance, and discusses its challenges and application prospects, so as to provide reference for the application of metabolomics in the study of important economic traits of pigs in the future.

Key words: metabolomics, metabolite, pig, economic traits

中图分类号:

S828.2

高志苗, 倪海花, 王彦平, 赵雪艳, 李菁璇, 王继英, 张勤. 代谢组学应用于猪重要经济性状遗传解析[J]. 畜牧兽医学报, 2025, 56(10): 4787-4795.

GAO Zhimiao, NI Haihua, WANG Yanping, ZHAO Xueyan, LI Jingxuan, WANG Jiying, ZHANG Qin. Application of Metabolomics in Genetic Analysis of Important Economic Traits in Pigs[J]. Acta Veterinaria et Zootechnica Sinica, 2025, 56(10): 4787-4795.

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代谢组学应用于猪重要经济性状遗传解析

Application of Metabolomics in Genetic Analysis of Important Economic Traits in Pigs

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