Sirtuins对雌性动物生殖的影响研究进展

doi:10.11843/j.issn.0366-6964.2019.12.002

摘要/Abstract

摘要： 沉默信息调节因子（silence information regulator，Sirtuins）为烟酰胺腺嘌呤二核苷酸依赖性组蛋白去乙酰化酶，可与组蛋白和多种转录因子结合，在调控卵巢储备、卵泡发育、卵母细胞成熟、颗粒细胞功能与胚胎发育等多个生理过程中发挥着重要功能。本文综述了Sirtuins对雌性动物生殖的影响，以期为Sirtuins深入研究提供依据。

关键词: Sirtuins, 雌性动物, 生殖

Abstract: Silence information regulator (Sirtuins) are nicotinamide adenine dinucleotide-dependent histone deacetylase, which can bind to histones and various transcription factors and play important roles in regulating ovarian reserve, follicular development, oocyte maturation, granulosa cell function and embryonic development. In this paper, the effects of Sirtuins on female reproduction were reviewed in order to provide basis for further study of Sirtuins.

Key words: Sirtuins, female animal, reproduction

中图分类号:

S814

房晓欢, 杜明, 李飒, 李俊杰, 王志刚. Sirtuins对雌性动物生殖的影响研究进展[J]. 畜牧兽医学报, 2019, 50(12): 2379-2386.

FANG Xiaohuan, DU Ming, LI Sa, LI Junjie, WANG Zhigang. Research Progress on the Effects of Sirtuins on Female Animal Reproduction[J]. Acta Veterinaria et Zootechnica Sinica, 2019, 50(12): 2379-2386.

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