单细胞转录组测序技术及其在动物繁殖中的应用进展

doi:10.11843/j.issn.0366-6964.2023.02.001

摘要/Abstract

摘要： 动物繁殖在动物种群发展和生命进化的过程中起到群落延续、物种演化、进化变异等至关重要的作用。繁殖是各种生殖细胞的动态变化和互作效应的结果，对生殖细胞动态变化机制进行解析是了解动物繁殖过程的基础。单细胞转录组测序技术在群体细胞中以单细胞维度深入解读信息，逐步成为解读细胞类群异质性、关键基因筛选、相关通路表达、细胞互作等具有复杂性、多样性、动态性的生物学问题的首要选择。目前，单细胞转录组测序技术已经开始从动物生殖细胞的角度对动物繁殖的相关机制进行更深入的探究，以此进一步研究动物繁殖的相关过程。因此，本文主要对单细胞转录组测序技术的相关内容以及其在动物繁殖中的相关应用进行总结。

关键词: 单细胞转录组测序, 动物繁殖, 生殖细胞

Abstract: Animal reproduction plays a crucial role in community continuation, species evolution, and evolutionary variation in animal population development and life evolution. Reproduction results from the dynamic changes and interaction effects of various germ cells. The analysis of the dynamic change mechanism of germ cells is the basis for understanding the reproductive process of animals. Single-cell transcriptome sequencing technology deeply interprets information in a single-cell dimension in population cells. It gradually becomes the primary choice for interpreting complexes, diverse and dynamic biological problems such as cell group heterogeneity, key gene screening, related pathway expression, and cell interaction. Currently, single-cell transcriptome sequencing technology has begun to explore the related mechanisms of animal reproduction from the perspective of animal germ cells to study the related processes of animal reproduction further. Therefore, this paper summarizes the related content of single-cell transcriptome sequencing technology and its application in animal reproduction.

Key words: single-cell transcriptome sequencing, animal reproduction, germ cells

中图分类号:

S814.8

刘源壹, 李昕俞, 巴音那木拉, 翠芳, 芒来, 杜明. 单细胞转录组测序技术及其在动物繁殖中的应用进展[J]. 畜牧兽医学报, 2023, 54(2): 421-433.

LIU Yuanyi, LI Xinyu, Bayinnamula, CUI Fang, MANG Lai, DU Ming. Single-Cell Transcriptome Sequencing Technology and its Application in Animal Reproduction[J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(2): 421-433.

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