畜牧兽医学报 ›› 2020, Vol. 51 ›› Issue (12): 2964-2971.doi: 10.11843/j.issn.0366-6964.2020.12.006

• 综述 • 上一篇    下一篇

奶牛乳腺炎金黄色葡萄球菌免疫逃避机制研究进展

刘丹丹1, 崔常勇2, 张弛1, 刘明江1,3*   

  1. 1. 扬州大学兽医学院, 扬州 225009;
    2. 龙口海关, 烟台 265700;
    3. 江苏省动物重要疫病与人畜共患病防控协同创新中心, 扬州 225009
  • 收稿日期:2020-06-01 出版日期:2020-12-25 发布日期:2020-12-23
  • 通讯作者: 刘明江,主要从事奶牛乳房炎的防治研究,E-mail:mjliu1@163.com
  • 作者简介:刘丹丹(1996-),女,重庆垫江人,硕士,主要从事奶牛乳房炎的防治研究,E-mail:dandanliuo@163.com
  • 基金资助:
    国家自然科学基金(31602097);江苏省高校优势学科建设工程资助项目

Research Progress on the Staphylococcus aureus Immune Evasion in Bovine Mastitis

LIU Dandan1, CUI Changyong2, ZHANG Chi1, LIU Mingjiang1,3*   

  1. 1. College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China;
    2. Long Kou Customhouse, Yantai 265700, China;
    3. Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou 225009, China
  • Received:2020-06-01 Online:2020-12-25 Published:2020-12-23

摘要: 金黄色葡萄球菌(Staphylococcus aureus,SA)型奶牛乳腺炎是一种较难控制的慢性、亚临床型传染病,给奶牛养殖业带来巨大的经济损失。多种SA免疫逃避机制在乳腺炎发生、发展过程中起重要作用,且SA的免疫逃避机制多与菌体毒力因子相关。本文对近年研究的奶牛乳腺炎SA的免疫逃避机制进行了综述,以期为SA型奶牛乳腺炎的防治研究提供参考。

关键词: 奶牛乳腺炎, 金黄色葡萄球菌, 免疫逃避

Abstract: Staphylococcus aureus(SA)bovine mastitis is a chronic and subclinical infectious disease, which is hard to control. It brings unpredictable losses to dairy-farming industry. Immune escape effect of SA plays an important role in the occurrence and development of mastitis, and some virulence factors are mostly associated with the immune evasion of bacteria. In this paper, some important immune evasion mechanisms of SA in recent researches were reviewed in order to provide theoretical reference for further prevention and treatment of mastitis in dairy cows.

Key words: bovine mastitis, Staphylococcus aureus, immune evasion

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