奶牛金葡菌乳房炎抗性的转录组及表观遗传学研究进展

doi:10.11843/j.issn.0366-6964.2022.02.001

摘要/Abstract

摘要： 奶牛乳房炎是一种常见疾病，对动物福利和奶牛场的经济效益产生不利影响。患有乳房炎的奶牛，尤其是金葡菌乳房炎的奶牛，其牛奶产量和品质大幅下降，严重的还会导致奶牛丧失生产能力。目前，奶牛乳房炎相关的研究已成为畜牧业的重点课题。本文综述和分析了近几年奶牛乳房炎及奶牛金葡菌乳房炎的主要研究领域和现状，主要对其抗病遗传育种在转录组学研究和表观遗传学研究等方面进行了详细综述，以期为奶业生产中奶牛乳房炎，尤其是金葡菌乳房炎的预防控制提供科学依据和参考。

关键词: 奶牛乳房炎, 金黄色葡萄球菌, 抗病遗传育种, 转录组, 表观遗传学

Abstract: Bovine mastitis is a common disease that has an adverse effect on animal welfare and the economic growth of dairy farms. A decrease in the milk production and quality is found in dairy cows with mastitis, especially those with Staphylococcus aureus (S. aureus) mastitis. Moreover, dairy cows with severe mastitis would even lose their production capacity. Research related to mastitis has become a key issue in the animal husbandry industry. The present article reviews and details the main research fields of bovine mastitis and S. aureus mastitis published in recent years, which mainly focus on the study of genetics and breeding of bovine mastitis resistance from the perspective of transcriptomics and epigenetics. A detailed review is expected to provide scientific basis and reference for the prevention and control of mastitis, especially S. aureus mastitis in dairy industry.

Key words: bovine mastitis, Staphylococcus aureus, breeding and genetics for disease resistance, transcriptome, epigenetics

中图分类号:

S823.91

王迪, 俞英. 奶牛金葡菌乳房炎抗性的转录组及表观遗传学研究进展[J]. 畜牧兽医学报, 2022, 53(2): 329-338.

WANG Di, YU Ying. Research Progress on Transcriptomics and Epigenetics of Bovine S. aureus Mastitis Resistance[J]. Acta Veterinaria et Zootechnica Sinica, 2022, 53(2): 329-338.

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