镉致肝损伤机制及硒拮抗镉肝毒性的研究进展

doi:10.11843/j.issn.0366-6964.2024.04.011

Abstract

Abstract: Cadmium is a toxic heavy metal that can accumulate in the body through the food chain, causing acute or chronic poisoning and posing a serious threat to the health of humans and livestock. Liver is the main target organ of cadmium toxicity injury. Therefore, it is of great significance to reveal the mechanism of cadmium hepatotoxicity and how to inhibit its toxic effect. Selenium is one of the essential trace elements in the human body and plays an important role in maintaining normal life activities. In recent years, many studies have shown that selenium has the effect of antagonizing cadmium hepatotoxicity. This article mainly summarizes the related studies on the mechanism of cadmium induced hepatotoxicity and the antagonism of selenium, hoping to provide reference for the prevention and treatment of cadmium pollution as well as the clinical application of selenium.

Key words: cadmium, hepatotoxicity, selenium, mechanism

CLC Number:

S856.5

LUO Tongwang, WU Ya, WANG Shujie, SONG Houhui, SHAO Chunyan. Research Progress on the Mechanism of Cadmium Induced Liver Damage and Selenium Antagonizing Cadmium Hepatotoxicity[J]. Acta Veterinaria et Zootechnica Sinica, 2024, 55(4): 1456-1466.

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Research Progress on the Mechanism of Cadmium Induced Liver Damage and Selenium Antagonizing Cadmium Hepatotoxicity

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