H5亚型流感病毒对人类和哺乳动物健康的威胁分析

doi:10.11843/j.issn.0366-6964.2025.09.009

Abstract

Abstract:

Highly pathogenic avian influenza (HPAI) H5 viruses have circulated in wild birds, causing widespread avian influenza outbreaks across various regions globally and significant economic losses to the poultry industry. Simultaneously, this subtype is persistently crossing species barriers and causing infections in a wide range of mammalian species, as well as in humans. In 2024, an unprecedented outbreak of HPAI H5N1 in dairy herds occurred in the USA, with the virus spreading within and between herds, and spilling over into humans, cats and poultry, which together indicated an increased public health risk. Here we present an overview of the evolution and epidemiology of H5 influenza viruses, examining the current dynamics of infection in both mammals and humans, and providing reference for the prevention and control of its public health and safety risks.

Key words: avian influenza virus, H5, species transmission, public health

CLC Number:

SUI Jinyu, WU Yunpu, LI Chao, WANG Suchun, PAN Junhui, QI Qian, WEI Shimeng, WANG Kaicheng. Analysis of the Threat Posed to Human and Mammalian Health by H5 Subtype Influenza Virus[J]. Acta Veterinaria et Zootechnica Sinica, 2025, 56(9): 4232-4240.

Figures/Tables 4

References 52

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统计指标 Statistical indicators	时间Time								合计 Total
统计指标 Statistical indicators	2003—2009	2010—2014	2015—2019	2020	2021	2022	2023	2024	合计 Total
病例数 Cases	468	233	160	1	2	6	12	72	954
死亡数 Deaths	282	125	48	0	1	1	4	3	464

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Analysis of the Threat Posed to Human and Mammalian Health by H5 Subtype Influenza Virus

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