Acta Veterinaria et Zootechnica Sinica ›› 2021, Vol. 52 ›› Issue (6): 1461-1470.doi: 10.11843/j.issn.0366-6964.2021.06.002

• REVIEW • Previous Articles     Next Articles

The Regulation Mechanism and Signal Pathway for Spine Formation in Vertebrate Embryo

LIU Qian, YUE Jingwei, NIU Naiqi, WANG Lixian*, ZHANG Longchao*   

  1. Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China
  • Received:2020-12-04 Online:2021-06-23 Published:2021-06-22

Abstract: The spine is the backbone of the mammalian body which has high heritability and important impact on carcass length. Its number varies among species, even within the same species, such as pigs and sheep. The number of vertebra is affected by the number of somites during the embryo development. In order to further explore the regulation mechanism of spine formation and quantity variation, this article reviews the embryonic development process of the spine, the formation and regulation of important intermediate structural somites. The aim of this review is to clarify the regulation mechanism of spine formation and development and provide theoretical basis and ideas for number of vertebrae breeding in economic animals.

Key words: spine, embryonic development, somites, signal pathway

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