整合生物学先验信息的全基因组选择方法及其在家畜育种中的应用进展

doi:10.11843/j.issn.0366-6964.2021.012.001

Abstract

Abstract: Compared to the traditional breeding methods, genomic selection (GS) accelerates the genetic progress of breeding by early selection and increasing the accuracy of selection for the individuals to be retained. It is unlikely shortened the generation interval by improving the GS methods. Therefore, how to improve the accuracy of GS to obtain additional genetic progress is the core issue of GS research. With the development of omics technology, it becomes possible to obtain multi-omics biological prior information from the public available databases or the in-house research. Therefore, how to integrate this useful biological prior information into GS models to improve the accuracy of GS has become an important topic in current animal breeding research. In this paper, the types of biological prior information and the GS methods that can integrate prior information is reviewed. Then,the application and prospects of these methods applied to livestock breeding is discussed. It is expected to provide useful information for the GS research that integrates biological prior information on livestock breeding.

Key words: biological prior information, genomic selection, livestock breeding, multi-omics

CLC Number:

S813.2

YUAN Zehu, GE Ling, LI Fadi, YUE Xiangpeng, SUN Wei. The Method of Genomic Selection by Integrating Biological Prior Information and Its Application in Livestock Breeding[J]. Acta Veterinaria et Zootechnica Sinica, 2021, 52(12): 3323-3334.

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The Method of Genomic Selection by Integrating Biological Prior Information and Its Application in Livestock Breeding

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