毒素-抗毒素系统在细菌生物被膜形成中的作用及调控机制

doi:10.11843/j.issn.0366-6964.2022.10.006

Abstract

Abstract: Toxin-antitoxin (T-A) system exists widely in bacterial genomes and plasmids, and regulates various physiological activities in bacteria. Bacterial biofilm formation is a survival strategy adopted by bacteria to adapt to stressful environments (adverse environments), which has strong antibiotic resistance and immune escape, and widely exists in nature. Biofilms have extensive harm and seriously threatens to the health of livestock, poultry and human. In this review, the roles and regulatory mechanisms of different types of T-A system in biofilm formation were summarized, aiming to better understand and master the roles and regulatory mechanisms of T-A system in biofilm formation, and lay a foundation for the removal and control of biofilm formation.

Key words: biofilm, toxin-antitoxin (T-A) system, bacteria

CLC Number:

S852.61

HOU Bo,WANG Chenyan,ZHOU Lunjiang. The Roles and Regulatory Mechanisms of Toxin-antitoxin System in Bacterial Biofilm Formation[J]. Acta Veterinaria et Zootechnica Sinica, 2022, 53(10): 3326-3334.

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The Roles and Regulatory Mechanisms of Toxin-antitoxin System in Bacterial Biofilm Formation

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