畜牧兽医学报 ›› 2024, Vol. 55 ›› Issue (8): 3344-3353.doi: 10.11843/j.issn.0366-6964.2024.08.008

• 综述 • 上一篇    下一篇

禽偏肺病毒的研究进展

张帆帆1(), 李杰茂2, 谭佳1, 黄江南1, 吴玲1, 韦启鹏1,*(), 康昭风1,*()   

  1. 1. 江西省农业科学院畜牧兽医研究所, 南昌 330200
    2. 井冈山大学生命科学院, 吉安 343009
  • 收稿日期:2023-07-25 出版日期:2024-08-23 发布日期:2024-08-28
  • 通讯作者: 韦启鹏,康昭风 E-mail:zfanfan0816@163.com;weiqp66@sina.com;kzf18579069658@163.com
  • 作者简介:张帆帆(1990-),男,江西吉安人,博士,主要从事动物病原学与致病机理研究, E-mail: zfanfan0816@163.com
  • 基金资助:
    江西省畜禽种业联合攻关项目(2022JXCQZY04);江西省家禽产业技术体系(JXARS-09);国家水禽产业技术体系(CARS-42-43);江西省农业科研协同创新项目(JXXTCXQN202101)

Research Progress on Avian Metapneumovirus

Fanfan ZHANG1(), Jiemao LI2, Jia TAN1, Jiangnan HUANG1, Ling WU1, Qipeng WEI1,*(), Zhaofeng KANG1,*()   

  1. 1. Institute of Animal Husbandry and Veterinary Medicine, Jiangxi Academy of Agricultural Sciences Jiangxi, Nanchang 330200, China
    2. School of Life Sceinces, Jinggangshan University, Ji'an 343009, China
  • Received:2023-07-25 Online:2024-08-23 Published:2024-08-28
  • Contact: Qipeng WEI, Zhaofeng KANG E-mail:zfanfan0816@163.com;weiqp66@sina.com;kzf18579069658@163.com

摘要:

禽偏肺病毒病是由禽偏肺病毒(avian metapneumovirus, aMPV)引起的一种以急性上呼吸道感染、产蛋和蛋壳质量下降为特征的疾病。aMPV可感染鸡、鸭、鸽等多种禽类,在全世界范围内广泛流行,给养禽业带来了巨大的经济损失。本文从病毒基因组结构及其编码蛋白、流行现状、致病特性、病毒感染诱导的宿主免疫应答以及其诊断技术与疫苗等方面对aMPV进行综述,为今后该疾病的诊断和预防提供科学依据。

关键词: 禽偏肺病毒, 病原学, 流行病学, 致病性, 诊断与防控

Abstract:

Avian metapneumovirus disease is an emerging viral infection caused by avian metapneumovirus (aMPV), an infectious disease characterized by acute upper respiratory tract infection and a severe decrease in egg production and eggshell quality of laying chicken. aMPV causes septicemic and exudative diseases of domestic ducks, geese and turkeys, leading to economically devastating to poultry industries. aMPV can infect chickens, ducks, pigeons and other birds, and is widely prevalent around the world, causing huge economic losses to the poultry industry. In this paper, we review aMPV in terms of genomic structure and its encoded proteins, epidemiological status, pathogenicity, infection-induced host immune response, and its diagnostic techniques and vaccines to provide a scientific basis for the diagnosis and prevention of the disease in the future.

Key words: avian metapneumovirus, etiology, epidemiology, pathogenicity, diagnosis and prevention

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