羊捻转血矛线虫病检测方法研究进展

doi:10.11843/j.issn.0366-6964.2024.04.015

摘要/Abstract

摘要： 羊捻转血矛线虫病是由捻转血矛线虫寄生于羊等小反刍动物皱胃内引起的一种危害严重的嗜血性寄生虫病。病羊临床表现为消瘦、贫血和衰弱等慢性消耗性症状，严重感染者可致死。该病在我国牧区普遍流行，目前暂无安全长效疫苗可用，加之耐药性严重，放牧羊群感染率和发病率居高不下，极大地降低了羊养殖业的经济效益。准确可靠的检测手段是诊断寄生虫感染、制定驱虫治疗方案、耐药监测及流行病学调查的关键环节。本文详细介绍了羊捻转血矛线虫病的检测技术研究现状，分析了病原学、免疫学及分子检测等方法的优缺点，并对未来检测技术发展趋势进行了展望，以期为该病新型检测方法的研发及综合防控策略提供参考。

关键词: 羊, 捻转血矛线虫, 病原学检测, 免疫学检测, 分子检测

Abstract: Ovine haemonchosis is a highly pathogenic, blood-sucking parasitic disease caused by Haemonchus contortus, which mainly resides in the abomasum of small ruminants like sheep. The infected sheep can manifest as some chronic wasting symptoms, such as emaciation, anemia, weakness, and even death in an acute form. Haemonchosis is widespread in pastoral areas in China. Due to the absence of the safe and long-term vaccine and presence of serious anthelmintic resistance, high prevalence and incidence in grazing sheep flocks still persist, which led to significantly economic losses to the sheep husbandry. Accurate and reliable detection remains an essential component for diagnosing parasite infections, making treatment decisions, monitoring anthelmintic resistance and conducting epidemiological investigation. This paper reviews in detail the current research situations of existing detection methods for ovine haemonchosis, including pathogen detection, immunological detection and molecular detection. The advantages and limitations of the above detection methods were evaluated, and the developmental trend for future detection techniques was prospected as well. The purpose of this review is to provide some available information and guideline for the novel methods development and comprehensive prevention and control strategies against ovine haemonchosis.

Key words: sheep, Haemonchus contortus, pathogen detection, immunological detection, molecular detection

中图分类号:

S852.731

张少华, 王帅, 邹扬, 刘仲藜, 才学鹏. 羊捻转血矛线虫病检测方法研究进展[J]. 畜牧兽医学报, 2024, 55(4): 1499-1510.

ZHANG Shaohua, WANG Shuai, ZOU Yang, LIU Zhongli, CAI Xuepeng. Advances in Detection Approaches for Ovine Haemonchosis[J]. Acta Veterinaria et Zootechnica Sinica, 2024, 55(4): 1499-1510.

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