畜牧兽医学报 ›› 2021, Vol. 52 ›› Issue (5): 1141-1153.doi: 10.11843/j.issn.0366-6964.2021.05.001

• 综述 • 上一篇    下一篇

奶牛热应激遗传机制研究知识图谱分析

张帆1,2, 张海亮2, 罗汉鹏2, 米思远2, 邱文卿2, 初芹3, 王雅春2*   

  1. 1. 新疆农业大学动物科学学院, 乌鲁木齐 830052;
    2. 中国农业大学动物科技学院, 北京 100193;
    3. 北京市农林科学院, 北京 100089
  • 收稿日期:2020-09-07 出版日期:2021-05-23 发布日期:2021-05-22
  • 通讯作者: 王雅春,主要从事分子及数量遗传学研究,E-mail:wangyachun@cau.edu.cn
  • 作者简介:张帆(1998-),男,辽宁葫芦岛人,硕士生,主要从事分子及数量遗传学研究,E-mail:19945846467@163.com
  • 基金资助:
    现代农业(奶牛)产业技术体系建设专项资金(CARS-36);长江学者和创新团队发展计划(IRT_15R62);国家自然科学基金外国青年学者研究基金项目(31750110459);北京三元种业科技股份有限公司自立科研课题(SYZYZ20190005)

Knowledge Mapping Analysis on Heat Stress Genetic Mechanisms Research of Dairy Cattle

ZHANG Fan1,2, ZHANG Hailiang2, LUO Hanpeng2, MI Siyuan2, QIU Wenqing2, CHU Qin3, WANG Yachun2*   

  1. 1. College of Animal Sciences, Xinjiang Agricultural University, Urumqi 830052, China;
    2. College of Animal Science and Technology, China Agricultural University, Beijing 100193, China;
    3. Beijing Academy of Agriculture and Forestry Sciences, Beijing 100089, China
  • Received:2020-09-07 Online:2021-05-23 Published:2021-05-22

摘要: 本文基于关键词共现分析和文献共引分析等计量学方法,分析了1990—2020年科学引文索引数据库所收录的奶牛热应激遗传机制领域共1 026条科技文献,统计了这些文献的作者、发文机构和年度发文量等,绘制了该领域共被引文献与关键词的共现网络图谱。重点通过高被引文献和高频关键词,透视了国际上该领域整体研究状况和研究热点,解读了该领域的发展脉络和趋势。此外,本文还通过中国知网数据库检索了国内在相关领域进行的研究,共检索到52篇文献,对国内在热应激遗传机制领域进行的研究进行了总结。通过国内外文献的关键词和文献共被引分析发现,热休克蛋白、单核苷酸多态性、氧化应激和繁殖性能一直是该领域的研究热点。随着研究的不断深入,热应激遗传机制研究从对热应激相关基因表达量的关注逐渐深入到对耐热多态的挖掘和对热应激相关基因表达调控的研究。在热应激基因表达过程中,表观修饰和miRNA是目前研究最广泛的两种调控方式。在奶牛热应激遗传机制研究领域,本文有助于我国研究人员宏观地了解本领域的研究现状及知识结构,快速定位首要关注点和重点文献。

关键词: 奶牛, 热应激, 遗传机制, 引文空间

Abstract: Based on keyword co-occurrence analysis and literature co-citation analysis, a total of 1 026 international scientific papers about genetic mechanisms of heat stress in dairy cattle from Science Citation Index database from 1990 to 2020 were analyzed, including the authors, institutions and the annual number of publications. The co-occurrence network of co-cited literatures and important keywords in this field also were drawn. By the literatures with high citation frequency and the keywords with high frequency, the overall research situation and hotspots were showed, and the development context and trend were interpreted in this field. Furthermore, based on 52 Chinese scientific papers in this field from CNKI database, the research progress on genetic mechanism of heat stress in dairy cattle in China was summarized. By the co-occurrence of keywords and co-citation analysis of literatures at home and abroad, it was found that heat shock proteins, single nucleotide polymorphisms, oxidative stress and reproductive performance were research hotspots in this field. With the deepening of research in this field, it has gradually developed from the expression analysis of genes to identifying single nucleotide polymorphisms related to heat-resistance and exploring the regulation mechanisms of genes related to heat stress in dairy cattle. In the expression regulation of genes related to heat stress, epigenetics and miRNA played important roles. In the genetic mechanisms research for heat stress in dairy cattle, this paper could be beneficial for understanding research situation and knowledge structure in this field, and help quickly finding the primary focus and key literature.

Key words: dairy cattle, heat stress, genetics mechanisms, citespace

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