畜牧兽医学报 ›› 2024, Vol. 55 ›› Issue (1): 22-30.doi: 10.11843/j.issn.0366-6964.2024.01.003

• 综述 • 上一篇    下一篇

能量负平衡影响奶牛卵泡发育的机制

曹建华1,2, 杨柏高1, 张培培1, 冯肖艺1, 张航1, 余洲1, 牛一凡1, 郝海生1, 杜卫华1, 朱化彬1, 杨凌2*, 赵学明1*   

  1. 1. 中国农业科学院北京畜牧兽医研究所, 北京 100193;
    2. 河北工程大学生命科学与食品工程学院, 邯郸 056038
  • 收稿日期:2023-07-10 出版日期:2024-01-23 发布日期:2024-01-24
  • 通讯作者: 赵学明,主要从事家畜胚胎生物技术研究,E-mail:zhaoxueming@caas.cn;杨凌,主要从事动物繁殖技术研究,E-mail:yangling@hebeu.edu.cn
  • 作者简介:曹建华(1998-),男,河北邯郸人,硕士生,主要从事动物繁殖研究,E-mail:jhcao0323@126.com
  • 基金资助:
    国家重点研发计划政府间重点专项(2022YFE0100200);国家自然科学基金国际合作项目(32161143032);农业农村部和财政部资助:现代农业产业技术体系资助(CARS-36);国家家养动物种质资源库;中国农业科学院科技创新工程(ASTIP-IAS06)

Mechanisms of Negative Energy Balance Affects Follicular Development in Dairy Cattle

CAO Jianhua1,2, YANG Baigao1, ZHANG Peipei1, FENG Xiaoyi1, ZHANG Hang1, YU Zhou1, NIU Yifan1, HAO Haisheng1, DU Weihua1, ZHU Huabin1, YANG Ling2*, ZHAO Xueming1*   

  1. 1. Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China;
    2. School of Life Sciences and Food Engineering, Hebei University of Engineering, Handan 056038, China
  • Received:2023-07-10 Online:2024-01-23 Published:2024-01-24

摘要: 奶牛能量负平衡(negative energy balance,NEB)是奶牛产后泌乳初期常会发生的一种代谢性疾病,当奶牛摄入能量无法满足其消耗能量时就会达到NEB状态。奶牛处于NEB状态时易引起患病率增加、妊娠率降低、生产性能下降,给集约化奶牛生产带来很大的经济损失。随着分子、组学技术的广泛应用,奶牛泌乳初期NEB对牛卵泡发育的影响机制得到进一步揭示。本文根据近年来相关报道,综述奶牛早期泌乳NEB对牛卵泡发育分子机制相关研究进展并进行展望,以期为减少NEB对奶牛繁殖性能的不利影响提供理论参考。

关键词: 能量负平衡, 奶牛, 泌乳期, 卵泡发育, 繁殖

Abstract: Negative energy balance (NEB) is a metabolic disease which often occurs in cows during the early postpartum lactation period, and the NEB status will be reached when the energy intake is not sufficient to meet the energy consumption. Cows in NEB status leads to the increase of cow disease rate, decrease of pregnancy rate, and decrease of production performance, which brings great economic losses to intensive dairy production. With the wide application of molecular and histological techniques, the mechanism of NEB effect on bovine follicular development in early lactation of cows has been further revealed. This paper reviewed the research progress related to the molecular mechanism of NEB on bovine follicular development in early lactation of dairy cows according to the studies in recent years and made an outlook, aiming to provide reference for the theory of reducing the adverse effects of NEB on the reproductive performance of dairy cows.

Key words: negative energy balance, dairy cattle, lactation period, follicles, reproduction

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