ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2016, Vol. 47 ›› Issue (6): 1075-1085.doi: 10.11843/j.issn.0366-6964.2016.06.001

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Research Advance on Sources,Pharmacological Effects and Detection Methods of Swainsonine

HUANG Xin,LIANG Jian-ping,GAO Xu-dong,HAO Bao-cheng*   

  1. (Key Laboratory of New Animal Drug Project of Gansu Province/Key Laboratory of Veterinary Pharmaceutical Development of Ministry of Agriculture,Lanzhou Institute of Husbandry and Pharmaceutical Sciences of CAAS,Lanzhou 730050,China)
  • Received:2015-12-07 Online:2016-06-23 Published:2016-06-23

Abstract:

Swainsonine,one of indole quinolizidine alkaloids,is a metabolite of locoweed and its parasitic fungi.The swainsonine has good anti-virus,anti-tumor effects and can enhance the role of immunity,has great potential for medicine development.This paper briefly expounds pharmacology,detection method,medicinal value and development potential of swansonine.And the research progress of its source and locoweed endophytic fungus synthesizing spherosin were summarized to enrich swainsonine’s source and provide the supply of abundant raw materials for its scientific and medical application.

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