ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2015, Vol. 46 ›› Issue (11): 1905-1915.doi: 10.11843/j.issn.0366-6964.2015.11.001

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Research Advances on Avian Leptin and Its Receptor

WANG Dan-dan,LI Yan-min,JIANG Rui-rui,KANG Xiang-tao,LIU Xiao-jun*   

  1. (International Joint Research Laboratory for Poultry Breeding of Henan,Henan Innovative Engineering Research Center of Poultry Germplasm Resource,College of Animal Science and Veterinary Medicine,Henan Agricultural University,Zhengzhou 450002,China)
  • Received:2015-01-09 Online:2015-11-23 Published:2015-11-23

Abstract:

 The authenticity of the so-called “chicken Leptin gene” was questioned since it was first reported in 1998.Actually it is not sure whether the Leptin gene exists in poultry genome until now.Although Leptin receptor gene had been widely confirmed in poultry,its physiological functions were still ambiguous due to the lack of endogenous Leptin.With the coming of the post genome age,it’s possible to look into the Leptin gene matter of avian species in wide scale and great depth.In 2014,3 laboratories independently reported the cloning and functional verification of Leptin gene in some wild birds.The findings greatly stimulated research interests in avian Leptin and Leptin receptor.We reviewed the latest advances in structure characteristics,origin and evolution,tissue distribution and “physiological functions” of Leptin and Leptin receptor gene in avian.

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