锰纳米佐剂的制备及生物学效应

doi:10.11843/j.issn.0366-6964.2024.08.011

Abstract

Abstract:

Manganese is an important trace element that participates in various physiological processes, including skeletal, reproductive, energy metabolism, and normal functioning of the nervous and immune systems. Compared with soluble manganese ions, nano-manganese can maintain the continuous release of manganese ions at the injection site, induce local immune responses, and enhance the cellular uptake of antigens by dendritic cells (DCs), promoting the activation and maturation of DCs in the body. This article reviews the relevant issues of nano-manganese from the perspectives of their mechanism of action, preparation methods, functional characterization, problems with nano adjuvants, and solutions. The application of nano-manganese as vaccine adjuvants was emphasized and the problems and solutions of nano-manganese were proposed.

Key words: nano-manganese, vaccines adjuvant, research progress

CLC Number:

S852.4

Mengdi WANG, Heng WANG, Xiuxiang LU, Yumin WANG, Wenjie FAN, Chen YAO, Pengxiang LIU, Yanjie MA, Guoyu YANG. Preparation of Nano-manganese and Its Biological Effects[J]. Acta Veterinaria et Zootechnica Sinica, 2024, 55(8): 3374-3382.

Figures/Tables 3

References 47

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Preparation of Nano-manganese and Its Biological Effects

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