非编码RNA作为犬肿瘤潜在生物标志物的研究进展

doi:10.11843/j.issn.0366-6964.2023.06.006

Abstract

Abstract: Canine tumor disease is a common disease in veterinary clinic with high incidence and great harm. It is one of the important causes of canine death, especially for middle-aged and elderly canines. In order to better diagnose and treat canine tumor diseases, it is of great significance to identify potential biomarkers and therapeutic targets. Non-coding RNA(ncRNA)refers to a class of RNA molecules that do not encode proteins and have many functions. ncRNA can regulate the development of tumor cells by regulating gene transcription and it is expected to become a biomarker and potential therapeutic target for the diagnosis and treatment of canine tumor diseases. Therefore, this article reviews the diagnostic value and application prospects of non-coding RNA in canine mammary tumors, melanoma and osteosarcoma, in order to provide new ideas for the diagnosis, prevention and treatment of canine tumors.

Key words: ncRNA, canine, tumors, biomarker

CLC Number:

S857.4

ZHANG Yan, LIU Jiayue, WU Meijin, ZHOU Jiahao, DIAO Hongxiu. Research Progress of Non-coding RNA as A Potential Biomarker for Canine Tumors[J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(6): 2264-2271.

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Research Progress of Non-coding RNA as A Potential Biomarker for Canine Tumors

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