Abstract: Canine intestinal lymphadenopathy is a rare protein-losing enteropathy that is very rare in veterinary practice. In this report, a case of an 8-year-old female Teddy is described with clinical signs of decreased appetite, occasional vomiting, persistent diarrhea, coarse and disheveled coat, abdominal enlargement and panting. Ultrasonographic examination revealed a well-defined stratification of the jejunal wall, moderate thickening of the mucosal layer, echogenic enhancement within the mucosal layer with unclear borders, non-uniformly distributed bright spot structures, and a small amount of ascites in the posterior part of the abdominal cavity. The dog was diagnosed with canine intestinal lymphadenopathy based on a comprehensive analysis of its medical history, clinical signs, hematological examination and imaging findings. Based on the conventional symptomatic therapeutic measures, a combination of improved recipes and medication was developed according to the actual prognosis. After more than two years of long-term maintenance treatment and prognostic follow-up, the dog showed significant weight gain, normalization of biochemical parameters, and significant improvement of intestinal symptoms on ultrasound imaging. This is the first report of a clinical case and treatment plan for canine intestinal lymphatic duct dilatation in China, which has reference value and significance for the diagnosis, treatment and research of related diseases in veterinary clinic.

Key words: intestinal lymphangiectasia, protein-losing enteropathy, canine, clinical diagnosis and treatment