ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2013, Vol. 44 ›› Issue (11): 1844-1850.doi: 10.11843/j.issn.0366-6964.2013.11.021

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Effects of N-carbamoylglutamate on Growth Performance and the Endogenous Anabolism of Arginine of Suckling Piglets

CAO Hong-zhan1,2, CHEN Nan1, LU Chun-lian1,2*   

  1. (1. College of Animal Science and Technology, Agricultural University of Hebei, Baoding 071000, China; 2. Institute of Swine Science, Agricultural University of Hebei, Baoding 071000, China)
  • Received:2012-12-17 Online:2013-11-23 Published:2013-11-23

Abstract:

This study was conducted to investigate the effects of oral administration of N-carbamoylglutamate on growth performance and the endogenous anabolism of arginine of suckling piglets from 7 to 21 days of age. The "Duroc × (Landrace × Yorkshire)" crossbred suckling piglets (n=30, 4-day-old) from 6 litters(same parity, 5 suckling piglets per litter) with similar weight((2.036±0.181) kg) were randomly allocated to five treatments (six replicates each), which were orally administrated at the dose of 0,100,150,200 and 250 mg·kg-1BW·d-1 NCG, respectivly. Result: Oral administration of 100 and 150 mg·kg-1 BW NCG significantly increased the average daily gain of suckling piglets compared with the control piglets (P<0.05).Oral administration of 150 mg·kg-1BW NCG significantly increased the plasma citrulline content of suckling piglets compared with the other suckling piglets (P<0.05). Oral administration of 100,150 and 200 mg·kg-1 BW NCG significantly increased the activity of carbamoyl phosphate synthase-I in duodenal of suckling piglets (P<0.05). Oral administration of 150 mg·kg-1 BW NCG significantly increased the gene expression of carbamoyl phosphate synthase-I in duodenal (P<0.05); 100 and 150 mg·kg-1 BW NCG significantly improved the gene expression of carbamoyl phosphate synthase-I(P<0.05) in jejunum and ileum. These results indicated that N-carbamoylglutamate could improve the growth performance and the endogenous anabolism of arginine of suckling piglets.

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