猪嗜血支原体猪体感染试验

doi:10.11843/j.issn.0366-6964.2013.10.019

Abstract

Abstract:

Porcine eperythrozoonosis (PE) caused by Mycoplasma suis (M. suis) infection is a febrile acute icteroanemia in pigs and human. In order to study the pathomechanism of PE, clinical symptoms, hematological parameters, M. suis loads, cellular and humoral immunity, gross pathology and histopathology were system recorded to monitor the process of this disease in models of splenectomized and non-splenectomized pigs. The result showed that the M. suis loads in splenectomized pigs maintain higher level (1.0×10⁸ copies per mL) and longer time than that of non-splenectomized pigs. Correlations between M. suis loads and the values of WBC, hematocrit, RBC and Fe were significant. The antibody against MSG1 was detected in only one pig, whereas the IL-4 and IFN-γ were not detected in all of the groups during the whole experiment. PE was reproduced and the process of this disease was recorded in this study which plays a fundamental role in revealing the pathomechanism, providing the guideline of prevention and diagnosis of this disease.

CLC Number:

S852.62

WANG Shuai-biao, LI Yu-feng, CHANG Chen, CHENG Wang-kun, MA Pei-pei, ZOU Yao. Study on Infection of Mycoplasma suis to Pigs[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2013, 44(10): 1645-1653.

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References

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Study on Infection of Mycoplasma suis to Pigs

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