牛支原体黏附素及黏附素结合蛋白研究进展

doi:10.11843/j.issn.0366-6964.2023.08.008

Abstract

Abstract: Mycoplasma bovis (M.bovis) is an important pathogen that infects cattle, which can lead to a variety of clinical symptoms such as pneumonia, arthritis, mastitis, keratoconjunctivitis and genital tractitis in infected cattle, causing huge economic losses to the cattle industry. M.bovis adhesins play an important role in pathogenesis of M.bovis, including pathogenic infection, cell invasion, immune evasion, and virulence production. So far, more than ten kinds of M.bovis adhesins have been identified. These adhesins primarily bind plasminogen (Plg), fibronectin (FN), heparin sulfate (HS), and amyloid precursor-like protein-2 (APLP2) of host cells. This article will review the current research status of M.bovis adhesins and their host cell target proteins, and provide reference for the identification and application of known and unknown adhesins of M.bovis.

Key words: M.bovis, adhesin, adhesin-binding protein

CLC Number:

S852.62

WU Qi, ZHANG Yujuan, LIU Tong, XIN Jiuqing, XU Qingyuan. Research Progress of Mycoplasma bovis Adhesins and Adhesin-binding Proteins[J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(8): 3206-3216.

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Research Progress of Mycoplasma bovis Adhesins and Adhesin-binding Proteins

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