基于基因组SNP和ROH的剑白香猪群体遗传结构解析

doi:10.11843/j.issn.0366-6964.2023.10.011

Abstract

Abstract: The purpose of this study was to analyze the population structure and genetic diversity of Jianbai Xiang pigs at the molecular level and to provide technical support for the identification and conservation of germplasm resources of Jianbai Xiang pigs. Using Porcine SNP50 BeadChip (Illumina, United States) to scan the whole genome SNP of 138 Jianbai Xiang pigs, the population structure of Jianbai Xiang pigs was studied by analyzing the principal component, genetic distance, genetic relationship and boar pedigree. The genetic diversity of the Jianbai Xiang pig was determined by ROH analysis. The results showed that there was no obvious stratification in this population, but it could be roughly divided into 3 parts. The average genetic distance within the population was about 0.273, and all boars were divided into 4 lineages. A total of 2 893 ROHs were detected in Jianbai Xiang pigs, with an average of 21 ROHs per individual. The average ROH length was 7.18 Mb and the average inbreeding coefficient (F_ROH) was 0.27%, indicating that the inbreeding accumulation of Jianbai Xiang pigs was small. A variety of analyses showed that the population had a moderate number of families, a small number of male animals in individual families, moderate genetic relationships between individuals, a low degree of inbreeding, and high genetic diversity. In this study, the population genetic structure and genetic diversity of Jianbai Xiang pigs were analyzed at the genome level, which provided the molecular basis for population rejuvenation and seed industry safety measures of Jianbai Xiang pigs.

Key words: Jianbai Xiang pig, population structure, ROH, SNP, genetic diversity

CLC Number:

S828.2

HU Ziping, WANG Ligang, ZONG Wencheng, HOU Renda, SU Yanfang, NIU Naiqi, WANG Lixian, WANG Yuan, ZHNAG Longchao. Genetic Structure Analysis of Jianbai Xiang Pig Population Based on Genomic SNP and ROH[J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(10): 4117-4125.

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Genetic Structure Analysis of Jianbai Xiang Pig Population Based on Genomic SNP and ROH

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