肠道微生物调控脂肪沉积及其代谢相关疾病的研究进展

doi:10.11843/j.issn.0366-6964.2024.10.003

Abstract

Abstract:

Adipose tissue is an important component of the body, which not only stores energy, protects tissues, and regulates body temperature, but also participates in metabolic regulation by secreting cytokines, playing an important role in the pathogenesis of obesity and related complications. Numerous studies have confirmed that, there exists a close relationship between gut microbiota and host fat metabolism and related diseases. This article reviews the main factors that gut microbiota affects fat deposition, including adipocytes, fatty acid composition, and fat related blood indicators. Exploring how gut microbiota participates in regulating fat absorption, generation, and decomposition processes through a series of pathways, and elaborating in detail the association between gut microbiota and diseases caused by lipid metabolism disorders. This article aims to improve and deepen the understanding of the regulation of fat deposition and related metabolic diseases by gut microbiota, providing a theoretical basis and reference for further research and clinical practice.

Key words: gut microbiota, fat, obesity, diabetes, MAFLD

CLC Number:

Q493.5

Lanmeng XU, Yuzhi HUANG, Yuzhu HAN, Changying LI, Jie ZHANG. Research Progress of Gut Microbiota Regulating Fat Deposition and Metabolic Related Diseases[J]. Acta Veterinaria et Zootechnica Sinica, 2024, 55(10): 4263-4277.

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Research Progress of Gut Microbiota Regulating Fat Deposition and Metabolic Related Diseases

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