Acta Veterinaria et Zootechnica Sinica ›› 2024, Vol. 55 ›› Issue (8): 3288-3296.doi: 10.11843/j.issn.0366-6964.2024.08.003

• Review • Previous Articles     Next Articles

Advances in the Study of Chicken Insulin Signaling Pathway

Ming LOU1,2,3(), Haoyu LUO1,2,3, Fang MU1,2,3, Hui LI1,2,3, Ning WANG1,2,3,*()   

  1. 1. Key Laboratory of Chicken Genetics and Breeding of Ministry of Agriculture and Rural Affairs, Harbin 150030, China
    2. Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province, Harbin 150030, China
    3. College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China
  • Received:2024-01-31 Online:2024-08-23 Published:2024-08-28
  • Contact: Ning WANG E-mail:lou_ming@neau.edu.cn;wangning@neau.edu.cn

Abstract:

Insulin is an essential hormone and plays crucial roles in a variety of biological processes including glucose and lipid metabolism, protein synthesis, growth, development, and trait formation. Chickens have natural insulin resistance, but the cause of chicken insulin resistance is still unknown. This review summarizes the research progress on the insulin signaling pathway in chicken liver, muscle and adipose tissue, and then proposes future research directions in chicken insulin signaling pathway and insulin resistance, with a view to providing new ideas for in-depth exploration of human insulin resistance and genetic improvement of chicken meat quality.

Key words: chicken, insulin signaling pathway, insulin resistance, liver, muscle, adipose tissue

CLC Number: