快大型黄羽肉鸡肉品质性状的遗传参数估计和关键基因挖掘

doi:10.11843/j.issn.0366-6964.2021.09.005

Abstract

Abstract: This experiment aimed to excavate the effective regions and key genes related to meat quality traits in fast-growing yellow-feather meat-type chickens. In this experiment, 1 923 fast-growing yellow-feather meat-type chickens were slaughtered at 56 days of age to measure carcass and meat quality traits, and genotyped with the customized chicken 55K SNP array. The genetic parameters for carcass and meat quality traits were estimated using the traditional best linear unbiased prediction (BLUP) and genomic best linear unbiased prediction (GBLUP) methods. The key QTL regions and genes were detected using genome-wide association study (GWAS). The results showed that the estimated heritability of pH, meat color L_{24 h}^* as a member of the solute vector family. In addition, the results showed that two haplotypes on chromosome 5 had extremely significant effects on pH and meat color traits. These results lay an important foundation for the optimization of genetic selection scheme and the development of molecular breeding technology for meat quality of yellow-feather meat-type chickens.

Key words: yellow-feather meat-type chickens, pH, meat color, genetic parameter, genome-wide association study(GWAS)

CLC Number:

S831.2

YANG Xinting, ZHENG Maiqing, TAN Xiaodong, ZHAO Guiping, HUANG Chao, LI Sen, LI Wei, WEN Jie, LIU Ranran. Genetic Parameters Estimation and Key Genes Identification for Meat Quality Traits of Fast-growing Yellow-feather Meat-type Chickens[J]. Acta Veterinaria et Zootechnica Sinica, 2021, 52(9): 2416-2428.

References 53

[1]	HUFF-LONERGAN E, LONERGAN S M.Mechanisms of water-holding capacity of meat:the role of postmortem biochemical and structural changes[J].Meat Sci, 2005, 71(1):194-204.
[2]	PEARCE K L, ROSENVOLD K, ANDERSEN H J, et al.Water distribution and mobility in meat during the conversion of muscle to meat and ageing and the impacts on fresh meat quality attributes-A review[J].Meat Sci, 2011, 89(2):111-124.
[3]	CARPENTER C E, CORNFORTH D P, WHITTIER D.Consumer preferences for beef color and packaging did not affect eating satisfaction[J].Meat Sci, 2001, 57(4):359-363.
[4]	SUMAN S P, JOSEPH P.Myoglobin chemistry and meat color[J].Annu Rev Food Sci Technol, 2013, 4:79-99.
[5]	GIDDINGS G G, HULTIN H O.Reduction of ferrimyoglobin in meat[J].C R C Crit Revi Food Technol, 1974, 5(2):143-173.
[6]	HELGELAND H, SODELAND M, ZORIC N, et al.Genomic and functional gene studies suggest a key role of beta-carotene oxygenase 1 like (bco1l) gene in salmon flesh color[J].Sci Rep, 2019, 9:20061.
[7]	FLETCHER D L.Poultry meat quality[J].World's Poult Sci J, 2002, 58(2):131-145.
[8]	FRAQUEZA M J, CARDOSO A S, FERREIRA M C, et al.Incidence of pectoralis major turkey muscles with light and dark color in a portuguese slaughterhouse[J].Poult Sci, 2006, 85(11):1992-2000.
[9]	WILKINS L J, BROWN S N, PHILLIPS A J, et al.Variation in the colour of broiler breast fillets in the UK[J].Br Poult Sci, 2000, 41(3):308-312.
[10]	孙皓.鸡肉类PSE肉与正常肉的功能特性的比较研究[D].南京:南京农业大学, 2013.SUN H.Comparison of functional properties of pse-like and normal chicken meat[D].Nanjing:Nanjing Agricultural University, 2013.(in Chinese)
[11]	FUJII J, OTSU K, ZORZATO F, et al.Identification of a mutation in porcine ryanodine receptor associated with malignant hyperthermia[J].Science (New York, N.Y.), 1991, 253(5018):448-451.
[12]	HARBITZ I, CHOWDHARY B, THOMSEN P D, et al.Assignment of the porcine calcium release channel gene, a candidate for the malignant hyperthermia locus, to the 6p11→q21 segment of chromosome 6[J].Genomics, 1990, 8(2):243-248.
[13]	MILAN D, JEON J T, LOOFT C, et al.A mutation in PRKAG3 associated with excess glycogen content in pig skeletal muscle[J].Science (New York, N.Y.), 2000, 288(5469):1248-1251.
[14]	ROY P L, NAVEAU J, ELSEN J M, et al.Evidence for a new major gene influencing meat quality in pigs[J].Genet Res, 1990, 55(1):33-40.
[15]	BARNES B R, MARKLUND S, STEILER T L, et al.The 5'-AMP-activated protein kinase γ3 isoform has a key role in carbohydrate and lipid metabolism in glycolytic skeletal muscle[J].J Biol Chem, 2004, 279(37):38441-38447.
[16]	FONTANESI L, DAVOLI R, COSTA L N, et al.Study of candidate genes for glycolytic potential of porcine skeletal muscle:identification and analysis of mutations, linkage and physical mapping and association with meat quality traits in pigs[J].Cytogenet Genome Res, 2003, 102(1-4):145-151.
[17]	FONTANESI L, DAVOLI R, COSTA L N, et al.Investigation of candidate genes for glycolytic potential of porcine skeletal muscle:association with meat quality and production traits in Italian Large White pigs[J].Meat Sci, 2008, 80(3):780-787.
[18]	BIHAN-DUVAL E L, NADAF J, BERRI C, et al.Detection of a Cis[corrected] eQTL controlling BCMO1 gene expression leads to the identification of a QTG for chicken breast meat color[J].PLoS One, 2011, 6(7):e14825.
[19]	HESSEL S, EICHINGER A, ISKEN A, et al.CMO1 deficiency abolishes vitamin A production from β-carotene and alters lipid metabolism in mice[J].J Biol Chem, 2007, 282(46):33553-33561.
[20]	NADAF J, GILBERT H, PITEL F, et al.Identification of QTL controlling meat quality traits in an F2 cross between two chicken lines selected for either low or high growth rate[J].BMC Genomics, 2007, 8:155.
[21]	NADAF J, BERRI C, DUNN I, et al.An expression QTL of closely linked candidate genes affects pH of meat in chickens[J].Genetics, 2014, 196(3):867-874.
[22]	BIHAN-DUVAL E L, HENNEQUET-ANTIER C, BERRI C, et al.Identification of genomic regions and candidate genes for chicken meat ultimate pH by combined detection of selection signatures and QTL[J].BMC Genomics, 2018, 19:294.
[23]	SUN Y F, ZHAO G P, LIU R R, et al.The identification of 14 new genes for meat quality traits in chicken using a genome-wide association study[J].BMC Genomics, 2013, 14:458.
[24]	LI Y, XU Z Y, LI H Y, et al.Differential transcriptional analysis between red and white skeletal muscle of Chinese Meishan pigs[J].Int J Biol Sci, 2010, 6(4):350-360.
[25]	刘冉冉, 赵桂苹, 文杰.鸡基因组育种和保种用SNP芯片研发及应用[J].中国家禽, 2018, 40(15):1-6.LIU R R, ZHAO G P, WEN J.Development of genome-wide SNP genotyping arrays for chicken breeding and conservation[J].China Poultry, 2018, 40(15):1-6.(in Chinese)
[26]	PURCELL S, NEALE B, TODD-BROWN K, et al.PLINK:a tool set for whole-genome association and population-based linkage analyses[J].Am J Hum Genet, 2007, 81(3):559-575.
[27]	GILMOUR A R, GOGEL B J, CULLIS B R, et al.ASReml user guide release 3.0 VSN International Ltd[R].Hemel Hempstead, UK:NSW Department of Industry and Investment, 2009.
[28]	ZHOU X, STEPHENS M.Genome-wide efficient mixed-model analysis for association studies[J].Nat Genet, 2012, 44(7):821-824.
[29]	BARRETT J C, FRY B, MALLER J, et al.Haploview:analysis and visualization of LD and haplotype maps[J]. Bioinformatics, 2005, 21(2):263-265.
[30]	李晶, 王杰, 康慧敏, 等.基于BLUP和GBLUP方法估计北京油鸡胴体和肉质性状遗传参数的差异[J].畜牧兽医学报, 2020, 51(1):35-42.LI J, WANG J, KANG H M, et al.The difference of genetic parameters for carcass and meat quality traits by BLUP and GBLUP methods in Beijing you chicken[J].Acta Veterinaria et Zootechnica Sinica, 2020, 51(1):35-42.(in Chinese)
[31]	ALNAHHAS N, BERRI C, BOULAY M, et al.Selecting broiler chickens for ultimate pH of breast muscle:analysis of divergent selection experiment and phenotypic consequences on meat quality, growth, and body composition traits[J].J Anim Sci, 2014, 92(9):3816-3824.
[32]	LE BIHAN-DUVAL E, BERRI C, BAEZA E, et al.Estimation of the genetic parameters of meat characteristics and of their genetic correlations with growth and body composition in an experimental broiler line[J].Poult Sci, 2001, 80(7):839-843.
[33]	CHABAULT M, BAÉZA E, GIGAUD V, et al.Analysis of a slow-growing line reveals wide genetic variability of carcass and meat quality-related traits[J].BMC Genet, 2012, 13:90.
[34]	LE BIHAN-DUVAL E, DEBUT M, BERRI C M, et al.Chicken meat quality:genetic variability and relationship with growth and muscle characteristics[J].BMC Genet, 2008, 9:53.
[35]	HARFORD I D, PAVLIDIS H O, ANTHONY N B.Divergent selection for muscle color in broilers[J].Poult Sci, 2014, 93(5):1059-1066.
[36]	NONNEMAN D J, SHACKELFORD S D, KING D A, et al.Genome-wide association of meat quality traits and tenderness in swine[J].J Anim Sci, 2013, 91(9):4043-4050.
[37]	CHUNG H Y, LEE K T, JANG G W, et al.A genome-wide analysis of the ultimate pH in swine[J].Genet Mol Res, 2015, 14(4):15668-15682.
[38]	周李生, 杨杰, 刘先先, 等.苏太猪宰后72 h pH和肉色性状的全基因组关联分析[J].中国农业科学, 2014, 47(3):564-573.ZHOU L S, YANG J, LIU X X, et al.Genome-wide association analyses for musle pH 72 h value and meat color traits in sutai pigs[J].Scientia Agricultura Sinica, 2014, 47(3):564-573.(in Chinese)
[39]	刘大鹏, 凡文磊, 唐静, 等.鸭胸肌肉色性状全基因组关联分析[J].中国畜牧兽医, 2020, 47(5):1326-1333.LIU D P, FAN W L, TANG J, et al.Genome-wide association studies on meat color traits in ducks[J].China Animal Husbandry & Veterinary Medicine, 2020, 47(5):1326-1333.(in Chinese)
[40]	DAVIS E, JENSEN C H, SCHRODER H D, et al.Ectopic expression of DLK1 protein in skeletal muscle of padumnal heterozygotes causes the callipyge phenotype[J].Curr Biol, 2004, 14(20):1858-1862.
[41]	LEE K, VILLENA J A, MOON Y S, et al.Inhibition of adipogenesis and development of glucose intolerance by soluble preadipocyte factor-1(Pref-1)[J].J Clin Invest, 2003, 111(4):453-461.
[42]	WADDELL J N, ZHANG P J, WEN Y F, et al.Dlk1 is necessary for proper skeletal muscle development and regeneration[J].PLoS One, 2010, 5(11):e15055.
[43]	SHIN J, LIM S, LATSHAW J D, et al.Cloning and expression of delta-like protein 1 messenger ribonucleic acid during development of adipose and muscle tissues in chickens[J].Poult Sci, 2008, 87(12):2636-2646.
[44]	BARZIK M, KOTOVA T I, HIGGS H N, et al.Ena/VASP proteins enhance actin polymerization in the presence of barbed end capping proteins[J].J Biol Chem, 2005, 280(31):28653-28662.
[45]	TSAI P C, SOONG B W, MADEMAN I, et al.A recurrent WARS mutation is a novel cause of autosomal dominant distal hereditary motor neuropathy[J].Brain, 2017, 140(5):1252-1266.
[46]	CRAWFORD N G, KELLY D E, HANSEN M E B, et al.Loci associated with skin pigmentation identified in African populations[J].Science (New York, N.Y.), 2017, 358(6365):eaan8433.
[47]	WIMMERS K, MURANI E, PONSUKSILI S.Functional genomics and genetical genomics approaches towards elucidating networks of genes affecting meat performance in pigs[J].Brief Funct Genomics, 2010, 9(3):251-258.
[48]	JANECKE A R, MAYATEPEK E, UTERMANN G.Molecular genetics of type 1 glycogen storage disease[J].Mol Genet Metab, 2001, 73(2):117-125.
[49]	HANEIN S, MARTIN E, BOUKHRIS A, et al.Identification of the SPG15 gene, encoding spastizin, as a frequent cause of complicated autosomal-recessive spastic paraplegia, including kjellin syndrome[J].Am J Hum Genet, 2008, 82(4):992-1002.
[50]	POINTER M A, MUNDY N I.Carotenoid genetics:chicken skin sheds light on carotenoid genetics[J].Heredity (Edinb), 2008, 101(5):393-394.
[51]	MORGAN J H L, PICKERING F S, EVERITT G C.Some factors affecting yellow fat colour in cattle[C]//Proceedings of the New Zealand Society of Animal Production, 1969.
[52]	LINDQVIST A, SHARVILL J, SHARVILL D E, et al.Loss-of-function mutation in carotenoid 15, 15'-monooxygenase identified in a patient with hypercarotenemia and hypovitaminosis A[J].J Nutr, 2007, 137(11):2346-2350.
[53]	VAN GOOR A, ASHWELL C M, PERSIA M E, et al.Quantitative trait loci identified for blood chemistry components of an advanced intercross line of chickens under heat stress[J].BMC Genomics, 2016, 17:287.

Genetic Parameters Estimation and Key Genes Identification for Meat Quality Traits of Fast-growing Yellow-feather Meat-type Chickens

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References 53

Related Articles 15

Recommended Articles

Metrics

Comments

[1]	WANG Xinxin, LIN Shumei, ZHAO Dongdong, WANG Xuesheng. Role of Exosomes Secreted by Alveolar Epithelial Cells in Regulating Macrophage Polarization in Acute Lung Injury [J]. Acta Veterinaria et Zootechnica Sinica, 2024, 55(1): 71-78.
[2]	SONG Wenyan, ZHANG Hanwen, WU Aodi, ZHANG Liyan, LIU Zhao, YE Tongtong, CHEN Chuangfu, SHENG Jinliang. Screening of Nanobodies against Porcine Reproductive and Respiratory Syndrome Virus GP5 Protein and Exploration of Their Inhibitory Effect on Virus Replication [J]. Acta Veterinaria et Zootechnica Sinica, 2024, 55(1): 258-270.
[3]	LIU Yueyang, LI Mengyuan, NIE Xueyi, MA Yabo, HOU Yuxin, MA Boli, YANG Yi, XU Jinrui. The Regulation of Calcium-binding Protein S100A4 on Autophagy in THP-1 Cells Infected with Bacillus Calmette-Guérin [J]. Acta Veterinaria et Zootechnica Sinica, 2024, 55(1): 311-322.
[4]	LI Keanning, DU Lili, AN Bingxing, DENG Tianyu, LIANG Mang, CAO Sheng, DU Yueying, XU Lingyang, GAO Xue, ZHANG Lupei, LI Junya, GAO Huijiang. Genetic Parameter Estimation and Genome-Wide Association Study for Carcass Traits and Primal Cuts Weight Traits in Huaxi Cattle [J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(9): 3664-3676.
[5]	XU Lei, ZHANG Menghua, ZHANG Tao, GENG Juan, FAN Shoumin, YANG Guangwei, GUO Yang, DENG Qiang, LI Jinzhi, LIU Jiangwei, HUANG Xixia, WANG Yachun. Genetic Parameter Estimates for Body Conformation in Xinjiang Brown Cattle Based on Principal Component Analysis and Factor Analysis [J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(9): 3677-3688.
[6]	MA Shujuan, XU Yijie, HE Ke, MA Ruifeng, ZHU Ying. Molecular Evolution and Expression Patterns of a Multigene Family of Toll-like Receptors in Ruminants [J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(9): 3722-3734.
[7]	WANG Zhiyuan, LIU Boqi, XU Zhiying, XU Sijia, XING Jiabao, ZHANG Guihong, WANG Heng, SUN Yankuo. Analysis of ORF5 Gene Variation of Porcine Reproductive and Respiratory Syndrome Virus in Local Regions of China from 2021 to 2022 [J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(9): 3812-3823.
[8]	ZHAO Yongpan, ZHENG Fangfang, YIN Junqing, DU Qian, TONG Dewen, HUANG Yong. Establishment and Application of Magnetic Nanoparticle Visualization Technique for Nucleic Acid Detection of Seven Common Swine Viruses [J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(9): 3848-3862.
[9]	WANG Hui, FENG Baoliang, WU Dan, XIANG Guangming, WANG Nan, MU Yulian, LI Kui, LIU Zhiguo. Research Progress of CD163 Gene and Disease-Resistant Breeding on Porcine Reproductive and Respiratory Syndrome [J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(8): 3127-3138.
[10]	WU Zhili, YAO Junhu, LEI Xinjian. Research Progress of Rumen-protected Glucose on Nutritional Regulation in Perinatal Dairy Animals [J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(8): 3173-3182.
[11]	LIU Xinhuan, YUN Jialei, MAO Li, LI Jizong, HAO Fei, HE Miaofeng, YANG Leilei, ZHANG Wenwen, CHENG Zilong, SUN Min, LIU Maojun, WANG Shaohui, BAI Juan, LI Wenliang. Isolation, Identification, Virulence Genes and Drug Resistance Analysis of Escherichia coli Isolated from Diarrheal Goat and Sheep [J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(8): 3445-3454.
[12]	WANG Jiandong, TANG Yulin, WANG Min, ZHANG Baosuo, YANG Fuqiang, GAO Haihui, YU Yang, GUO Yansheng. The Mechanism of Lycium barbarum Polysaccharide against Immunosuppression Induced by Cyclophosphamide in Chicks Based on RNA-Seq Technique [J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(8): 3519-3532.
[13]	ZHANG Xumei, WEI Yurong, XU Chenghui, YANG Tong, SHI Huijun, FU Qiang, YANG Li. To Analyze the Mechanism of Berberine in the Treatment of Salmonella Gallinarum Infection Based on Network Pharmacology and Experimental Verification [J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(8): 3557-3570.
[14]	GONG Zhiguo, ZHAO Jiamin, GU Baichen, REN Peipei, YU Zhuoya, BAI Yunjie, LIU Xinyu, WANG Chao, LIU Bo. Exploring the Mechanism of Codonopsis pilosula in Alleviation of Acute Lung Injury in Escherichia coli Infected Mice Based on Network Pharmacology [J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(8): 3571-3581.
[15]	YANG Qing, GONG Jing, ZHAO Xueyan, ZHU Xiaodong, GENG Liying, ZHANG Chuansheng, WANG Jiying. Comparison of Array and Resequencing in Pig Genetic Structure Studies [J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(7): 2772-2782.