环状RNA及其在生殖发育中的研究进展

doi:10.11843/j.issn.0366-6964.2020.09.001

Abstract

Abstract: Circular RNA (circ-RNA) is a class of closed circular RNA molecules formed by reverse splicing of the initial transcriptional RNA, which are expressed abundantly in eukaryocytic cells. circ-RNA exists stably for a long period because of the resistance to RNA exonuclease. The expression of genes is regulated by cornpetitive binding of miRNA via sponge absorption. Recent studies demonstrated that circ-RNA molecular identification and physiological regulation had become the focus of life science research. In this review, we summarized the biogenesis of circ-RNA, the role in regulating early embryonic development, and the quantity and effects during the gamete development.

Key words: circ-RNA, formation, reproductive development, gene expression

CLC Number:

S813.1

CHEN Huifang, YANG Tianhao, CAI Jianfeng, LI Chao, BAI Yinshan. Circular RNA and Its Research Progress in Reproductive Development[J]. Acta Veterinaria et Zootechnica Sinica, 2020, 51(9): 2039-2047.

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Circular RNA and Its Research Progress in Reproductive Development

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