ADIPOQ基因单体型与不同性别绵羊生长性状的关联分析

doi:10.11843/j.issn.0366-6964.2018.04.021

Abstract

Abstract:

The aims of this study were to analyze the effect of haplotypes of ADIPOQ gene on growth traits in male and female lambs, to filter haplotypes of ADIPOQ gene which had different effects on growth traits of male and female lambs, and to provide basis for improving the efficiency of production and breeding improvement. The mutations and haplotypes of ADIPOQ gene were detected in total 1 185 New Zealand Romney lambs (556 male and 629 female) by using PCR-SSCP method. The relationship between haplotypes and growth traits of male and female lambs was investigated using GLMs model. The effects of haplotypes of ADIPOQ on ovine growth traits were estimated and the haplotypes which had differents effects on growth traits of male and female lambs were identified. The results showed that ovine ADIPOQ gene had rich nucleotide mutations and haplotypes, and the frequencies of haplotypes were different in male and female lambs (haplotypes D₁-A₂ and D₁-C₂ were only detected in female lambs in this study). The associations analysis results showed that haplotypes of ovine ADIPOQ gene had different effects on growth traits of male and female lambs. In male lambs, the presence of A₁-A₂ was associated with decreased tailing weight (P=0.033), weaning weight (P=0.020) and pre-weaning growth rate (P=0.026). No associations were detected between the other haplotypes and growth traits of male lambs. No associations were found between the ADIPOQ haplotypes and growth traits of female lambs. Frequencies of ovine ADIPOQ haplotypes are different, and haplotypes may have different effects on growth traits of male and female lambs. The presence of A₁-A₂ is associated with decreased growth production, and may be used as a theoretical guidance for improving the growth performance of male lambs.

CLC Number:

S826.2

AN Qing-ming, ZHOU Hui-tong, LIU Xiu, LI Shao-bin, LUO Yu-zhu, JON G. Hickford. Effect of Haplotypes of ADIPOQ on Growth Traits in Ovine with Different Genders[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2018, 49(4): 825-832.

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Effect of Haplotypes of ADIPOQ on Growth Traits in Ovine with Different Genders

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