母羊下丘脑-垂体-性腺轴调控其子宫复旧机制研究进展

doi:10.11843/j.issn.0366-6964.2025.06.001

摘要/Abstract

摘要：

子宫复旧是动物繁殖过程中的重要环节, 其复旧程度决定母畜能否成功受孕。母畜分娩后子宫复旧的完成通常受到营养、产后护理和分娩季节等因素影响。反刍动物子宫复旧主要通过下丘脑-垂体-性腺轴(hypothalamic-pituitary-gonadal axis, HPGA) 来调控。然而, 目前对母羊子宫复旧机制方面的研究尚不系统, HPGA调控母羊子宫复旧的机制尚不明析。基于此, 本文将从母羊子宫复旧机制、子宫复旧影响因素以及子宫复旧过程中HPGA的作用机制方面进行综述, 以期为深入理解HPGA对母羊子宫复旧的重要性提供参考, 为HPGA调控母羊子宫复旧机制的深入研究提供理论依据。

关键词: 母羊, 子宫复旧, 下丘脑-垂体-性腺轴, 调控机制

Abstract:

Uterine involution represents a crucial component of the reproductive process in animals, with the extent of involution being a key determinant of whether a female animal can achieve subsequent pregnancy. The completion of uterine involution in female animals postpartum is influenced by a variety of factors, including nutrition, postpartum care, and the season of parturition. In ruminants, this process is primarily regulated by the hypothalamic-pituitary-gonadal axis (HPGA). However, current research on the mechanisms underlying uterine involution in ewes remains fragmented, and the specific regulatory pathways of the HPGA in this context are not yet fully elucidated. This review aims to comprehensively examine the mechanisms of uterine involution in ewes, the factors influencing this process, and the role of the HPGA. It is intended to provide a foundational reference for a deeper understanding of the significance of the HPGA in uterine involution in ewes and to offer a theoretical basis for future research into the regulatory mechanisms of the HPGA in this area.

Key words: ewe, uterine involution, hypothalamic-pituitary-gonadal axis, regulatory mechanism

中图分类号:

S826.3

马青玲, 王志有, 侯生珍, 杨超. 母羊下丘脑-垂体-性腺轴调控其子宫复旧机制研究进展[J]. 畜牧兽医学报, 2025, 56(6): 2525-2536.

MA Qingling, WANG Zhiyou, HOU Shengzhen, YANG Chao. Research Progress on the Regulation of Uterine Involution in Ewes by the Hypothalamic-Pituitary-Gonadal Axis[J]. Acta Veterinaria et Zootechnica Sinica, 2025, 56(6): 2525-2536.

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