母牛发情鉴定标记研究进展

doi:10.11843/j.issn.0366-6964.2024.11.001

畜牧兽医学报 ›› 2024, Vol. 55 ›› Issue (11): 4785-4795.doi: 10.11843/j.issn.0366-6964.2024.11.001

母牛发情鉴定标记研究进展

杨书含¹(), 时玉新², 庞云渭¹, 原开敏¹^,³, 修豪宇¹^,⁴, 汪超¹^,³, 路永强⁵^,*(), 王栋¹^,*()

1. 中国农业科学院北京畜牧兽医研究所，北京 100193
2. 内蒙古赤峰市敖汉旗农牧局，赤峰 024300
3. 吉林农业大学动物科学技术学院，长春 130118
4. 山西农业大学动物科学学院，太谷 030801
5. 北京市畜牧兽医总站，北京 100107

收稿日期:2024-04-25 出版日期:2024-11-23 发布日期:2024-11-30
通讯作者: 路永强,王栋 E-mail:3312270752@qq.com;luyongqiang@163.com;dwangcn2002@vip.sina.com
作者简介:杨书含(2000-)，男，贵州镇远人，硕士，主要从事动物遗传育种与繁殖研究，E-mail: 3312270752@qq.com
基金资助:
科技创新2030(2023ZD0404903);国家重点研发计划(2023YFD1300601)

Research Progress of Estrus Identification Markers in Cows

Shuhan YANG¹(), Yuxin SHI², Yunwei PANG¹, Kaimin YUAN¹^,³, Haoyu XIU¹^,⁴, Chao WANG¹^,³, Yongqiang LU⁵^,*(), Dong WANG¹^,*()

1. Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China
2. Aohan Animal Husbandry Bureau, Chifeng 024300, China
3. College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China
4. College of Animal Science, Shanxi Agricultural University, Taigu 030801, China
5. Animal Husbandry Station of Beijing, Beijing 100107, China

Received:2024-04-25 Online:2024-11-23 Published:2024-11-30
Contact: Yongqiang LU, Dong WANG E-mail:3312270752@qq.com;luyongqiang@163.com;dwangcn2002@vip.sina.com

摘要/Abstract

摘要：

牛场规模化程度不断扩大，个体发情的精准鉴定成为繁殖管理重点。行为表现、生理变化与自身卵泡发育密切相关，是鉴别发情母牛、确定最佳配种时间的重要标记。利用现代科技深入揭示这些标记的发情周期变化规律与调控机制，提高自动化发情鉴定效率成为该领域的研究焦点。为此，本文综述了母牛发情行为变化、生理特征的国内外研究进展，分析了相关发情鉴定技术存在的问题，并回顾了发情母牛唾液、尿液、乳汁特异化合物的研究状况，旨在为研发新型高效的发情鉴定自动化技术提供参考。

关键词: 母牛, 发情鉴定, 行为标记, 生理标记, 分子标记

Abstract:

With increasing scaled cattle cultivation, estrus accurate identification of individual has become the management focus of breeding. The performance of behavior and physiological changes, which are important markers in distinguishing estrus cows and determining the optimal insemination time, are closely related to itself follicular development. A better knowledge of the regularity and mechanism of these markers by modern technology during estrus cycle would help to improve the efficiency of automated estrus identification and become the focus in this field. Therefore, this paper reviews the research progress on estrus behavior and physiological characteristics of cow, analyzes the existing related issues in estrus identification techniques, and summarizes the recent research on identification of specific compounds of saliva, urine and milk in estrus cows, aiming to provide reference for developing newly efficient automated estrus identification technologies.

Key words: cows, estrus identification, behavior marker, physiological marker, molecular marker

中图分类号:

S823.3

杨书含, 时玉新, 庞云渭, 原开敏, 修豪宇, 汪超, 路永强, 王栋. 母牛发情鉴定标记研究进展[J]. 畜牧兽医学报, 2024, 55(11): 4785-4795.

Shuhan YANG, Yuxin SHI, Yunwei PANG, Kaimin YUAN, Haoyu XIU, Chao WANG, Yongqiang LU, Dong WANG. Research Progress of Estrus Identification Markers in Cows[J]. Acta Veterinaria et Zootechnica Sinica, 2024, 55(11): 4785-4795.

参考文献 82

1	周正义, 田莉, 田宏志, 等.母牛安静发情鉴定技术概况及影响因素分析[J].畜牧兽医学报,2021,52(4):862-871.
	ZHOU Z Y , TIAN L , TIAN H Z , et al.Analysis of identification technology and influence factors on silent estrus of cows[J].Acta Veterinaria et Zootechnica Sinica,2021,52(4):862-871.
2	李拓.母牛的发情周期以及发情的鉴定方法[J].中国动物保健,2022,24(7):83-84. doi: 10.3969/j.issn.1008-4754.2022.07.042
	LI T .The estrous cycle of the cow and the identification method of estrus[J].China Animal Health,2022,24(7):83-84. doi: 10.3969/j.issn.1008-4754.2022.07.042
3	REITH S , HOY S .Review: behavioral signs of estrus and the potential of fully automated systems for detection of estrus in dairy cattle[J].Animal,2018,12(2):398-407. doi: 10.1017/S1751731117001975
4	万仁华.正确判断母牛发情与适时人工授精[J].中国畜牧业,2022,(19):53-54.
	WAN R H .Judging oestrus of cow correctly and carrying out artificial insemination timely[J].China Animal Industry,2022,(19):53-54.
5	GAUDE I , KEMPF A , STRVVE K D , et al.Estrus signs in Holstein Friesian dairy cows and their reliability for ovulation detection in the context of visual estrus detection[J].Livest Sci,2021,245,104449. doi: 10.1016/j.livsci.2021.104449
6	MONDAL M , RAJKHOWA C , PRAKASH B S .Behavioral estrous signs can predict the time of ovulation in mithun (Bos frontalis)[J].Theriogenology,2006,66(5):1391-1396. doi: 10.1016/j.theriogenology.2006.04.033
7	宋亚攀, 孙丽萍, 郭爱珍, 等.涂蜡笔方法在母牛发情鉴定中的应用[J].中国奶牛,2014,(15):60-62. doi: 10.3969/j.issn.1004-4264.2014.15.017
	SONG Y P , SUN L P , GUO A Z , et al.Application of crayon method in cow estrus identification[J].China Dairy Cattle,2014,(15):60-62. doi: 10.3969/j.issn.1004-4264.2014.15.017
8	刘忠超, 刘勇军.基于Android的奶牛发情爬跨行为无线监测系统设计[J].黑龙江畜牧兽医,2019,(8):55-59, 179.
	LIU Z C , LIU Y J .Design of wireless monitoring system for cow estrus crawling behavior based on Android[J].Heilongjiang Animal Science and Veterinary Medicine,2019,(8):55-59, 179.
9	WALKER W L , NEBEL R L , MCGILLIARD M L .Time of ovulation relative to mounting activity in dairy cattle[J].J Dairy Sci,1996,79(9):1555-1561. doi: 10.3168/jds.S0022-0302(96)76517-7
10	SAINT-DIZIER M , CHASTANT-MAILLARD S .Potential of connected devices to optimize cattle reproduction[J].Theriogenology,2018,112,53-62. doi: 10.1016/j.theriogenology.2017.09.033
11	LODKAEW T , PASUPA K , LOO C K .CowXNet: an automated cow estrus detection system[J].Expert Syst Appl,2023,211,118550. doi: 10.1016/j.eswa.2022.118550
12	BAI Q , GAO R H , WANG R , et al.X3DFast model for classifying dairy cow behaviors based on a two-pathway architecture[J].Sci Rep,2023,13(1):20519. doi: 10.1038/s41598-023-45211-2
13	顾静秋, 王志海, 高荣华, 等.基于融合图像与运动量的奶牛行为识别方法[J].农业机械学报,2017,48(6):145-151.
	GU J Q , WANG Z H , GAO R H , et al.Recognition method of cow behavior based on combination of image and activities[J].Transactions of the Chinese Society for Agricultural Machinery,2017,48(6):145-151.
14	WU D H , WANG Y F , HAN M X , et al.Using a CNN-LSTM for basic behaviors detection of a single dairy cow in a complex environment[J].Comput Electron Agric,2021,182,106016. doi: 10.1016/j.compag.2021.106016
15	王政, 许兴时, 华志新, 等.融合YOLO v5n与通道剪枝算法的轻量化奶牛发情行为识别[J].农业工程学报,2022,38(23):130-140. doi: 10.11975/j.issn.1002-6819.2022.23.014
	WANG Z , XU X S , HUA Z X , et al.Lightweight recognition for the oestrus behavior of dairy cows combining YOLO v5n and channel pruning[J].Transactions of the Chinese Society of Agricultural Engineering,2022,38(23):130-140. doi: 10.11975/j.issn.1002-6819.2022.23.014
16	WANG R , BAI Q , GAO R H , et al.Oestrus detection in dairy cows by using atrous spatial pyramid and attention mechanism[J].Biosyst Eng,2022,223,259-276. doi: 10.1016/j.biosystemseng.2022.08.018
17	谢忠红, 刘悦怡, 宋子阳, 等.基于时序运动特征的奶牛爬跨行为识别研究[J].南京农业大学学报,2021,44(1):194-200.
	XIE Z H , LIU Y Y , SONG Z Y , et al.Research on recognition of crawling behavior of cows based on temporal motion features[J].Journal of Nanjing Agricultural University,2021,44(1):194-200.
18	GUO Y Y , ZHANG Z R , HE D J , et al.Detection of cow mounting behavior using region geometry and optical flow characteristics[J].Comput Electron Agric,2019,163,104828. doi: 10.1016/j.compag.2019.05.037
19	岳帅. 基于计算机视觉的奶牛夜间爬跨预警系统开发[D]. 杨凌: 西北农林科技大学, 2023.
	YUE S. Computer vision-based cows' nocturnal mounting early warning system development[D]. Yangling: Northwest A&F University, 2023. (in Chinese)
20	王少华. 基于视频分析和深度学习的奶牛爬跨行为检测方法研究[D]. 杨凌: 西北农林科技大学, 2021.
	WANG S H. Detection methods of cow mounting behavior based on video analysis and dee learning[D]. Yangling: Northwest A&F University, 2021. (in Chinese)
21	蔡兆晖, 林学杰.基于机器视觉的奶牛发情行为视频监测算法研究[J].当代畜禽养殖业,2021,(3):28-30. doi: 10.3969/j.issn.1005-5959.2021.03.010
	CAI Z H , LIN X J .Research on video monitoring algorithm of milk cow estrus behavior based on machine vision[J].Modern Livestock and Poultry Breeding Industry,2021,(3):28-30. doi: 10.3969/j.issn.1005-5959.2021.03.010
22	MA S F , ZHANG Q R , LI T F , et al.Basic motion behavior recognition of single dairy cow based on improved Rexnet 3D network[J].Comput Electron Agric,2022,194,106772. doi: 10.1016/j.compag.2022.106772
23	CODL R , DUCHÁČEK J , VACEK M , et al.Relationship between daily activities duration and oestrus in dairy cows over the year[J].Acta Vet Brno,2022,91(1):11-16. doi: 10.2754/avb202291010011
24	ZHOU X J , XU C , GOMES LOPES M , et al.Characterization of the physical and ruminal activities related to estrus in dairy cows raised on Chinese commercial farms[J].Vet Arh,2023,93(2):143-158. doi: 10.24099/vet.arhiv.1533
25	STRAPÁK P , MIČIAKOVÁ M , STRAPÁKOVÁ E , et al.Influence of estrus on changes of locomotion activity and rumination time in cattle dams[J].Acta Fytotech Zootech,2021,24,127-130. doi: 10.15414/afz.2021.24.mi-prap.127-130
26	ZEBARI H M , RUTTER S M , BLEACH E C L .Characterizing changes in activity and feeding behaviour of lactating dairy cows during behavioural and silent oestrus[J].Appl Anim Behav Sci,2018,206(6):12-17.
27	潘予琮, 蒋林树, 熊本海.奶牛产后首次发情行为变化规律及影响因素分析[J].中国畜牧杂志,2021,57(4):123-128.
	PAN Y C , JIANG L S , XIONG B H , et al.Analysis on the change rules and influencing factors of first estrus behavior in postpartum dairy cows[J].Chinese Journal of Animal Science,2021,57(4):123-128.
28	REITH S , HOY S .Relationship between daily rumination time and estrus of dairy cows[J].J Dairy Sci,2012,95(11):6416-6420. doi: 10.3168/jds.2012-5316
29	PAHL C , HARTUNG E , MAHLKOW-NERGE K , et al.Feeding characteristics and rumination time of dairy cows around estrus[J].J Dairy Sci,2015,98(1):148-154. doi: 10.3168/jds.2014-8025
30	SCHIRMANN K , CHAPINAL N , WEARY D M , et al.Rumination and its relationship to feeding and lying behavior in Holstein dairy cows[J].J Dairy Sci,2012,95(6):3212-3217. doi: 10.3168/jds.2011-4741
31	BRAUN U , TRÖSCH L , NYDEGGER F , et al.Evaluation of eating and rumination behaviour in cows using a noseband pressure sensor[J].BMC Vet Res,2013,9,164. doi: 10.1186/1746-6148-9-164
32	SHEN W Z , CHENG F , ZHANG Y , et al.Automatic recognition of ingestive-related behaviors of dairy cows based on triaxial acceleration[J].Information Processing in Agriculture,2020,7(3):427-443. doi: 10.1016/j.inpa.2019.10.004
33	孙雅琳. 基于边缘计算的奶牛反刍行为实时监测研究[D]. 哈尔滨: 东北农业大学, 2023.
	SUN Y L. Research on real-time monitoring of dairy cow rumination behavior based on edge computing[D]. Harbin: Northeast Agricultural University, 2023. (in Chinese)
34	毛燕茹. 基于机器视觉的多目标奶牛反刍行为监测方法研究[D]. 杨凌: 西北农林科技大学, 2022.
	MAO Y R. Multi-target rumination behavior monitoring method of dairy cows based on machine vision[D]. Yangling: Northwest A&F University, 2022. (in Chinese)
35	LI J X , LIU Y H , ZHENG W X , et al.Monitoring cattle ruminating behavior based on an improved keypoint detection model[J].Animals (Basel),2024,14(12):1791.
36	陈甜甜. 基于计算机视觉的牛反刍行为识别与分析[D]. 包头: 内蒙古科技大学, 2023.
	CHEN T T. Recognition and analysis of cattle's rumination based on computer vision[D]. Baotou: Inner Mongolia University of Science & Technology, 2023. (in Chinese)
37	姬江涛, 刘启航, 高荣华, 等.基于改进FlowNet 2.0光流算法的奶牛反刍行为分析方法[J].农业机械学报,2023,54(1):235-242.
	JI J T , LIU Q H , GAO R H , et al.Ruminant behavior analysis method of dairy cows with improved FlowNet 2.0 optical flow algorithm[J].Transactions of the Chinese Society for Agricultural Machinery,2023,54(1):235-242.
38	郭冠华. 奶牛发情期躯体不同部位活动量变化规律研究[D]. 太谷: 山西农业大学, 2022.
	GUO G H. Study on the changing law of the activity of different parts of the body of dairy cows during estrus[D]. Taigu: Shanxi Agricultural University, 2022. (in Chinese)
39	ROELOFS J B , VAN EERDENBURG F J C M , SOEDE N M , et al.Pedometer readings for estrous detection and as predictor for time of ovulation in dairy cattle[J].Theriogenology,2005,64(8):1690-1703. doi: 10.1016/j.theriogenology.2005.04.004
40	MAYO L M , SILVIA W J , RAY D L , et al.Automated estrous detection using multiple commercial precision dairy monitoring technologies in synchronized dairy cows[J].J Dairy Sci,2019,102(3):2645-2656. doi: 10.3168/jds.2018-14738
41	蒋晓新, 刘炜, 魏星远, 等.运用计步器鉴定泌乳盛期荷斯坦奶牛的发情效果研究[J].安徽农业科学,2013,41(15):6728-6729, 6732. doi: 10.3969/j.issn.0517-6611.2013.15.058
	JIANG X X , LIU W , WEI X Y , et al.Study on the effects of identifying the estrus of holstein cows during peak lactation by using pedometer[J].Journal of Anhui Agricultural Sciences,2013,41(15):6728-6729, 6732. doi: 10.3969/j.issn.0517-6611.2013.15.058
42	SAKAGUCHI M , FUJIKI R , YABUUCHI K , et al.Reliability of Estrous detection in holstein heifers using a radiotelemetric pedometer located on the neck or legs under different rearing conditions[J].J Reprod Dev,2007,53(4):819-828. doi: 10.1262/jrd.18099
43	曹学浩, 黄善琦, 马树刚, 等.活动量监测技术的研究及其在奶牛繁殖管理中的应用[J].中国奶牛,2013,(8):37-40. doi: 10.3969/j.issn.1004-4264.2013.08.008
	CAO X H , HUANG S Q , MA S G , et al.Applications of activity monitoring technology in dairy cattle breeding management[J].China Dairy Cattle,2013,(8):37-40. doi: 10.3969/j.issn.1004-4264.2013.08.008
44	孙保贵. 奶牛运动量辅助发情诊断及电导率辅助乳房炎诊断参数的研究[D]. 泰安: 山东农业大学, 2011.
	SUN B G. A study on parameters for estrus detection based on activity record and subclinical mastitis diagnosis based on milk conductivity in lactating cows[D]. Taian: Shandong Agricultural University, 2011. (in Chinese)
45	胡仁超. 荷斯坦牛活动量变化规律及其影响因素的相关性研究[D]. 杨凌: 西北农林科技大学, 2016.
	HU R C. Researches on variation of the walking activity and it's influencing factors of holstein cattle[D]. Yangling: Northwest A&F University, 2016. (in Chinese)
46	VALENZA A , GIORDANO J O , LOPES G JR , et al.Assessment of an accelerometer system for detection of estrus and treatment with gonadotropin-releasing hormone at the time of insemination in lactating dairy cows[J].J Dairy Sci,2012,95(12):7115-7127. doi: 10.3168/jds.2012-5639
47	DOLECHECK K A , SILVIA W J , HEERSCHE G JR , et al.Behavioral and physiological changes around estrus events identified using multiple automated monitoring technologies[J].J Dairy Sci,2015,98(12):8723-8731. doi: 10.3168/jds.2015-9645
48	HIGAKI S , OKADA H , SUZUKI C , et al.Estrus detection in tie-stall housed cows through supervised machine learning using a multimodal tail-attached device[J].Comput Electron Agric,2021,191,106513. doi: 10.1016/j.compag.2021.106513
49	VOß A L , FISCHER-TENHAGEN C , BARTEL A , et al.Sensitivity and specificity of a tail-activity measuring device for calving prediction in dairy cattle[J].J Dairy Sci,2021,104(3):3353-3363. doi: 10.3168/jds.2020-19277
50	SCHILKOWSKY E M , GRANADOS G E , SITKO E M , et al.Evaluation and characterization of estrus alerts and behavioral parameters generated by an ear-attached accelerometer-based system for automated detection of estrus[J].J Dairy Sci,2021,104(5):6222-6237. doi: 10.3168/jds.2020-19667
51	SCHWEINZER V , GUSTERER E , KANZ P , et al.Evaluation of an ear-attached accelerometer for detecting estrus events in indoor housed dairy cows[J].Theriogenology,2019,130,19-25. doi: 10.1016/j.theriogenology.2019.02.038
52	STEVENSON J S , HILL S L , NEBEL R L , et al.Ovulation timing and conception risk after automated activity monitoring in lactating dairy cows[J].J Dairy Sci,2014,97(7):4296-4308. doi: 10.3168/jds.2013-7873
53	和占星, 张继才, 黄梅芬, 等.不同繁殖生理阶段及繁殖障碍母牛的阴道黏液电阻值变化[J].畜牧与饲料科学,2023,44(5):57-62.
	HE Z X , ZHANG J C , HUANG M F , et al.Characterization of changes in electrical resistance of vaginal mucus of beef cows in different reproductive physiological periods and with different types of reproductive disorders[J].Animal Husbandry and Feed Science,2023,44(5):57-62.
54	寇红祥. 奶牛体温与活动量自动检测系统设计研发及发情周期规律研究[D]. 长春: 吉林农业大学, 2017.
	KOU H X. Design of automatic detection system for body temperature and activity and the research on oestrus regulation of dairy cows[D]. Changchun: Jilin Agricultural University, 2017. (in Chinese)
55	ANDERSSON L M , OKADA H , MIURA R , et al.Wearable wireless estrus detection sensor for cows[J].Comput Electron Agric,2016,127,101-108. doi: 10.1016/j.compag.2016.06.007
56	刘忠超, 何东健.奶牛阴道植入式电阻传感器与无线监测系统研究[J].农业机械学报,2019,50(11):175-185. doi: 10.6041/j.issn.1000-1298.2019.11.020
	LIU Z C , HE D J .Research of implantable sensor and wireless monitoring system for cow's vaginal resistance[J].Transactions of the Chinese Society for Agricultural Machinery,2019,50(11):175-185. doi: 10.6041/j.issn.1000-1298.2019.11.020
57	葛利江, 吴志杰, 陈建鳌, 等.关于奶牛发情周期及围产期体温变化规律的研究[J].黑龙江畜牧兽医,1995,(11):3-5.
	GE L J , WU Z J , CHEN J A , et al.Variations in body temperature in dairy cows Druing the estrous cycle and Periparturient period[J].Heilongjiang Animal Science and Veterinary Medicine,1995,(11):3-5.
58	KIM J Y , LEE J S , JO Y H , et al.Measuring the effects of estrus on rumen temperature and environment, behavior and physiological attributes in Korean native breeding cattle[J].J Anim Sci Technol,2023,65(3):579-587. doi: 10.5187/jast.2022.e117
59	HIGAKI S , MIURA R , SUDA T , et al.Estrous detection by continuous measurements of vaginal temperature and conductivity with supervised machine learning in cattle[J].Theriogenology,2019,123,90-99. doi: 10.1016/j.theriogenology.2018.09.038
60	王祯. 基于温度分布特征的奶牛发情识别关键技术的研究[D]. 呼和浩特: 内蒙古农业大学, 2022.
	WANG Z. Research on the key technology of cow estrus based on temperature distribution characteristics[D]. Hohhot: Inner Mongolia Agricultural University, 2022. (in Chinese)
61	修豪宇, 李迎军, 原开敏, 等.母牛发情期间躯体不同部位温度变化规律研究进展[J].畜牧兽医学报,2024,55(4):1381-1388.
	XIU H Y , LI Y J , YUAN K M , et al.Research progress of temperature variation in different parts of body during estrus in cows[J].Acta Veterinaria et Zootechnica Sinica,2024,55(4):1381-1388.
62	RANDI F , MCDONALD M , DUFFY P , et al.The relationship between external auditory canal temperature and onset of estrus and ovulation in beef heifers[J].Theriogenology,2018,110,175-181. doi: 10.1016/j.theriogenology.2018.01.001
63	WANG S L , ZHANG H L , TIAN H Z , et al.Alterations in vaginal temperature during the estrous cycle in dairy cows detected by a new intravaginal device—a pilot study[J].Trop Anim Health Prod,2020,52(5):2265-2271. doi: 10.1007/s11250-020-02199-5
64	屈东东. 群养奶牛体温实时监测系统设计与实现[D]. 合肥: 安徽农业大学, 2017.
	QU D D. Design and implementation of monitoring system for multiple cows body temperature[D]. Hefei: Anhui Agricultural University, 2017. (in Chinese)
65	何东健, 宋子琪.基于热红外成像与骨架树模型的奶牛眼温自动检测[J].农业机械学报,2021,52(3):243-250.
	HE D J , SONG Z Q .Automatic detection of dairy cow's eye temperature based on thermal infrared imaging technology and skeleton tree model[J].Transactions of the Chinese Society for Agricultural Machinery,2021,52(3):243-250.
66	辛海云, 孟繁明, 胡斌, 等.唾液在家畜发情鉴定中的应用进展[J].畜牧与兽医,2020,52(7):136-139.
	XIN H Y , MENG F M , HU B , et al.Application of saliva in animal estrus detection[J].Animal Husbandry & Veterinary Medicine,2020,52(7):136-139.
67	SANKAR R , ARCHUNAN G , HABARA Y .Detection of oestrous-related odour in bovine (Bos taurus) saliva: bioassay of identified compounds[J].Animal,2007,1(9):1321-1327. doi: 10.1017/S1751731107000614
68	KARTHIKEYAN K , MANIVANNAN P , RAJESH D , et al.Identification of p-cresol as an estrus-specific volatile in buffalo saliva: comparative docking analysis of buffalo OBP and β-lactoglobulin with p-cresol[J].Zoolog Sci,2014,31(1):31-36. doi: 10.2108/zsj.31.31
69	董智豪, 时玉新, 郭冠华, 等.母牛不同发情阶段唾液化合物的比较分析[J].畜牧兽医学报,2023,54(11):4636-4652.
	DONG Z H , SHI Y X , GUO G H , et al.Comparative analysis of salivary compounds in different estrous stages of cows[J].Acta Veterinaria et Zootechnica Sinica,2023,54(11):4636-4652.
70	CHAVAN N B , KUMARESAN A , CHHILLAR S , et al.Salivary crystallization pattern: a possible unconventional tool for timing of insemination and early pregnancy diagnosis in zebu cows[J].J Dairy Sci,2023,90(1):21-25.
71	SINGH L K , PANDEY M , BAITHALU R K , et al.Comparative proteome profiling of saliva between estrus and non-estrus stages by employing label-free quantitation (LFQ) and Tandem Mass Tag (TMT)-LC-MS/MS analysis: an approach for estrus biomarker identification in Bubalus bubalis[J].Front Genet,2022,13,867909. doi: 10.3389/fgene.2022.867909
72	贾银海. 基于唾液蛋白组学开发鉴定水牛发情方法的研究[D]. 南宁: 广西大学, 2019.
	JIA Y H. Research on the estrus identification method of the development based on the salivary proteomics in the buffalo[D]. Nanning: Guangxi University, 2019. (in Chinese)
73	BARMAN P , YADAV M C , KUMAR H , et al.Gas chromatographic-mass spectrometric analysis of chemical volatiles in buffalo (Bubalus bubalis) urine[J].Theriogenology,2013,80(6):654-658. doi: 10.1016/j.theriogenology.2013.06.012
74	RAJANARAYANAN S , ARCHUNAN G .Identification of urinary sex pheromones in female buffaloes and their influence on bull reproductive behaviour[J].Res Vet Sci,2011,91(2):301-305. doi: 10.1016/j.rvsc.2010.12.005
75	董智豪, 张秋雪, 郭冠华, 等.牛发情特异信息素的研究进展[J].畜牧兽医学报,2022,53(4):1010-1018.
	DONG Z H , ZHANG Q X , GUO G H , et al.Study progress on specific pheromones of bovine during oestrus[J].Acta Veterinaria et Zootechnica Sinica,2022,53(4):1010-1018.
76	MUTHUKUMAR S , MUNIASAMY S , SRINIVASAN M , et al.Evaluation of pheromone-based kit: a noninvasive approach of estrus detection in buffalo[J].Reprod Domest Anim,2018,53(6):1466-1472.
77	VARRA M , SUNDARESAN N R , KUMAR V G , et al.Tamm-horsfall protein expression in urine of buffaloes at the estrus and diestrus stages of estrous cycle[J].Agric Sci Dig,2024,43(6):858-863.
78	FOROUTAN A , GUO A C , VAZQUEZ-FRESNO R , et al.Chemical composition of commercial cow's milk[J].J Agric Food Chem,2019,67(17):4897-4914.
79	DU C , NAN L K , LI C F , et al.Influence of estrus on the milk characteristics and mid-infrared spectra of dairy cows[J].Animals (Basel),2021,11(5):1200.
80	ZEBARI H M , RUTTER S M , BLEACH E C L .Fatty acid profile of milk for determining reproductive status in lactating Holstein Friesian cows[J].Anim Reprod Sci,2019,202,26-34.
81	ZHAO C , BAI Y L , FU S X , et al.Comparison of metabolic alterations in serum and milk whey between inactive ovaries and estrus dairy cows[J].Front Vet Sci,2021,7,609391.
82	LIU W J , DU C , NAN L K , et al.Influence of estrus on dairy cow milk exosomal miRNAs and their role in hormone secretion by granulosa cells[J].Int J Mol Sci,2023,24(11):9608.

[1]	牛佳佳, 徐丹, 刘洋, 赵小玲. 鸡芦花羽性状遗传调控机制研究进展[J]. 畜牧兽医学报, 2024, 55(5): 1883-1892.
[2]	修豪宇, 李迎军, 原开敏, 汪超, 杨书含, 吕丽华, 王栋. 母牛发情期间躯体不同部位温度变化规律研究进展[J]. 畜牧兽医学报, 2024, 55(4): 1381-1388.
[3]	杨书含, 沙里金, 庞云渭, 修豪宇, 汪超, 王禹恒, 何信逢, 原开敏, 路永强, 王栋. 母牛安静发情的特征及原因分析[J]. 畜牧兽医学报, 2024, 55(11): 4808-4818.
[4]	余洲, 杨柏高, 李崇阳, 张培培, 曹建华, 牛一凡, 覃广胜, 赵学明. 不同发情阶段水牛唾液的DIA定量蛋白组学分析[J]. 畜牧兽医学报, 2024, 55(11): 5072-5084.
[5]	余洲, 杨柏高, 张航, 徐茜, 张培培, 冯肖艺, 曹建华, 牛一凡, 杜卫华, 郝海生, 朱化彬, 阿布力孜·吾斯曼, 赵学明. 奶水牛发情标记物的研究进展[J]. 畜牧兽医学报, 2023, 54(9): 3623-3630.
[6]	董智豪, 时玉新, 郭冠华, 原开敏, 修豪宇, 汪超, 白俊艳, 王栋. 母牛不同发情阶段唾液化合物的比较分析[J]. 畜牧兽医学报, 2023, 54(11): 4636-4652.
[7]	李亭亭, 刘秋月, 李向臣, 王海涛. 绵羊经济性状相关基因研究进展及其应用[J]. 畜牧兽医学报, 2022, 53(8): 2417-2434.
[8]	董智豪, 张秋雪, 郭冠华, 段晨莹, 赵羚均, 白俊艳, 王栋. 牛发情特异信息素的研究进展[J]. 畜牧兽医学报, 2022, 53(4): 1010-1018.
[9]	邱清华, 欧阳克蕙, 苏华维, 曹兵海. 异性孪生母牛的可育性鉴别和利用进展[J]. 畜牧兽医学报, 2021, 52(6): 1471-1480.
[10]	周正义, 田莉, 田宏志, 李茹意, 段晨莹, OBIANWUNA Uchechukwu Edna, 吕丽华, 王栋. 母牛安静发情鉴定技术概况及影响因素分析[J]. 畜牧兽医学报, 2021, 52(4): 862-871.
[11]	田宏志, 陈晓丽, 李欣, 李茹意, 王栋. 同期排卵处理母牛体温和活动量变化规律及效果分析[J]. 畜牧兽医学报, 2020, 51(7): 1619-1627.
[12]	刘晓静, 刘璐, 王杰, 崔焕先, 赵桂苹, 文杰. 鸡血糖性状的全基因组关联分析[J]. 畜牧兽医学报, 2020, 51(6): 1187-1195.
[13]	李蓝祁, 刘江静, 陈晓丽, 李欣, 路永强, 王水莲, 王栋. 奶牛发情期活动量变化规律研究[J]. 畜牧兽医学报, 2018, 49(7): 1387-1393.
[14]	寇红祥, 李蓝祁, 王振玲, 任康, 李树静, 路永强, 王栋. 牛发情期活动量与阴道黏液电阻值变化规律的研究[J]. 畜牧兽医学报, 2017, 48(7): 1221-1228.
[15]	徐怀超,昝林森,王洪宝,宁越. CRTC3基因多态性及基因型组合与秦川牛生长性状的关联分析[J]. 畜牧兽医学报, 2016, 47(11): 2184-2190.

母牛发情鉴定标记研究进展

Research Progress of Estrus Identification Markers in Cows

PDF

可视化

摘要/Abstract

引用本文

使用本文

参考文献 82

相关文章 15

编辑推荐

Metrics

本文评价