Abstract:

One Tembusu virus named BZ was inoculated to 7-day-old ducks. One week later, the incidence rate of 100% and the mortality rate of 80% occurred. Most of duck organs showed the systemic symptoms of congestion, hemorrhage and necrosis. The pathological changes showed severe liver parenchymal degeneration and necrosis; Spleen lymphocytes partial reduced; Renal tubular epithelial cell swelled; Pulmonary congestion, a large number of cells overflowed; Visible coagulation necrosis in the pancreas; Brain congestion and edema, meningeal inflammatory cell of cerebellar infiltrated. Compared with those of control group, the activities of serum alanine aminotransferase(ALT), aspartate aminotransferase (AST), gamma glutamyltransferase (GGT), lactic dehydrogenase (LDH) and concentration of uric acid (UA) in virus-attacked ducks were obviously increased. The results showed that the pathogenic mechanisms of the virus may be associated with cell necrosis and multiple organ injury and exhaustion.