[1] ANDERSON R C, DALZIEL J E, GOPAL P K, et al. The role of intestinal barrier function in early life in the development of colitis[M]//FUKATA M. Colitis. Rijeka:IntechOpen, 2012:26-54. [2] CAMILLERI M. Leaky gut:mechanisms, measurement and clinical implications in humans[J]. Gut, 2019, 68(8):1516-1526. [3] ZHU C, WU Y P, JIANG Z Y, et al. Dietary soy isoflavone attenuated growth performance and intestinal barrier functions in weaned piglets challenged with lipopolysaccharide[J]. Int Immunopharmacol, 2015, 28(1):288-294. [4] SU D, WEN X B, MA T, et al. Effects of hydroxytyrosol on growth performance, antioxidant capacity and intestinal inflammatory factors in broilers[J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(11):4851-4859. (in Chinese) 苏丹, 文晓宾, 马腾, 等. 羟基酪醇对肉仔鸡生长性能、抗氧化能力和肠道炎性因子的影响[J]. 畜牧兽医学报, 2023, 54(11):4851-4859. [5] VEREDIANO T A, MARTINO H S D, PAES M C D, et al. Effects of anthocyanin on intestinal health:a systematic review[J]. Nutrients, 2021, 13(4):1331. [6] GU X H, ZHANG H F, SHE R P, et al. Effect of weaning age on small intestine morphology in piglets[J]. Acta Veterinaria et Zootechnica Sinica, 2001, 32(4):306-313. (in Chinese) 顾宪红, 张宏福, 佘锐萍, 等. 断奶日龄对仔猪肠粘膜形态的影响[J]. 畜牧兽医学报, 2001, 32(4):306-313. [7] YUAN D X, WANG J, XIAO D F, et al. Eucommia ulmoides flavones as potential alternatives to antibiotic growth promoters in a low-protein diet improve growth performance and intestinal health in weaning piglets[J]. Animals, 2020, 10(11):1998. [8] CHEN J S, KANG B J, ZENG J G, et al. Effects of dietary sanguinarine on growth performance, intestinal mucosal morphology and immune function of small intestinal mucosa of weaned piglets[J]. Chinese Journal of Animal Nutrition, 2018, 30(5):1845-1853. (in Chinese) 陈家顺, 康宝聚, 曾建国, 等. 血根碱对断奶仔猪生长性能、肠道形态结构及小肠黏膜免疫功能的影响[J]. 动物营养学报, 2018, 30(5):1845-1853. [9] CSERNUS B, BIRÓ S, BABINSZKY L, et al. Effect of carotenoids, oligosaccharides and anthocyanins on growth performance, immunological parameters and intestinal morphology in broiler chickens challenged with Escherichia coli lipopolysaccharide[J]. Animals, 2020, 10(2):347. [10] JIANG S Q, CHEN Z L, ZHANG S, et al. Protective effects of protocatechuic acid on growth performance, intestinal barrier and antioxidant capacity in broilers challenged with lipopolysaccharide[J]. Animal, 2023, 17(1):100693. [11] WU Y J, JIANG H H, ZHU E P, et al. Hericium erinaceus polysaccharide facilitates restoration of injured intestinal mucosal immunity in Muscovy duck reovirus-infected Muscovy ducklings[J]. Int J Biol Macromol, 2018, 107:1151-1161. [12] LI C Y, NIU J L, LIU Y X, et al. The effects of oregano essential oil on production performance and intestinal barrier function in growing Hyla rabbits[J]. Ital J Anim Sci, 2021, 20(1):2165-2173. [13] ZHENG C, LI F D, LI F, et al. Effects of tannic acid addition in milk replacer on development of gastrointestinal tract of 7 to 28 days old Hu lambs[J]. Scientia Agricultura Sinica, 2019, 52(21):3924-3933. (in Chinese) 郑琛, 李发弟, 李飞, 等. 代乳粉添加单宁酸对7-28日龄湖羊羔羊胃肠道发育的影响[J]. 中国农业科学, 2019, 52(21):3924-3933. [14] LI Y, MENG X Y, LING Y, et al. Effects of tea saponin on intestinal mucosa morphology and intestinal flora of Anhui white goat[J]. Journal of Yangzhou University:Agricultural and Life Science Edition, 2021, 42(5):25-32. (in Chinese) 李玉, 孟新月, 凌嫄, 等. 茶皂素对安徽白山羊小肠黏膜形态及肠道菌群的影响[J]. 扬州大学学报(农业与生命科学版), 2021, 42(5):25-32. [15] ZHUANG S, MING K, MA N, et al. Portulaca oleracea L. polysaccharide ameliorates lipopolysaccharide-induced inflammatory responses and barrier dysfunction in porcine intestinal epithelial monolayers[J]. J Funct Foods, 2022, 91:104997. [16] XU C, WANG K, DING Y H, et al. Claudin-7 gene knockout causes destruction of intestinal structure and animal death in mice[J]. World J Gastroentero, 2019, 25(5):584-599. [17] WAN S Z, LIU C, HUANG C K, et al. Ursolic acid improves intestinal damage and bacterial dysbiosis in liver fibrosis mice[J]. Front Pharmacol, 2019, 10:1321. [18] RAKA R N, XIAO J S, WU H, et al. Pingyin rose essential oil restores intestinal barrier integrity in DSS-induced mice colitis model[J]. Food Res Int, 2023, 164:112362. [19] WANG Y, SUN W J, WU E Y, et al. Polysaccharides from Abrus cantoniensis hance modulate intestinal microflora and improve intestinal mucosal barrier and liver oxidative damage induced by heat stress[J]. Front Vet Sci, 2022, 9:868433. [20] BRUNING E E, COLLER J K, WARDILL H R, et al. Site-specific contribution of Toll-like receptor 4 to intestinal homeostasis and inflammatory disease[J]. J Cell Physiol, 2021, 236(2):877-888. [21] TANG X P, LIU H, YANG S F, et al. Epidermal growth factor and intestinal barrier function[J]. Mediat Inflamm, 2016, 2016:1927348. [22] REISINGER N, STEINER T, NITSCH S, et al. Effects of a blend of essential oils on broiler performance and intestinal morphology during coccidial vaccine exposure[J]. J Appl Poultry Res, 2011, 20(3):272-283. [23] MEI C, HE S S, YIN P, et al. Magnolol pretreatment attenuates heat stress-induced IEC-6 cell injury[J]. J Zhejiang Univ-SCI B, 2016, 17(6):413-424. [24] REN Z H, GUO C Y, YU S M, et al. Progress in mycotoxins affecting intestinal mucosal barrier function[J]. Int J Mol Sci, 2019, 20(11):2777. [25] MEI H D, LI Y F, MA X Y, et al. Effects and regulatory mechanisms of quercetin on animal intestinal mucosal barrier function[J]. Chinese Journal of Animal Nutrition, 2022, 34(9):5475-5488. (in Chinese) 梅华迪, 李袁飞, 马现永, 等. 槲皮素对动物肠道黏膜屏障功能的影响及其调控机制[J]. 动物营养学报, 2022, 34(9):5475-5488. [26] XIONG X J, CHEN W Y, CUI J L, et al. Effecte of Uvsolic acid on promoting bile secretion in rat[J]. Acta Chinese Medicine and Pharmacology, 2003, 31(4):54-55. (in Chinese) 熊筱娟, 陈蔚云, 崔江龙, 等. 乌索酸对大鼠胆汁的影响[J]. 中医药学报, 2003, 31(4):54-55. [27] VOLSTATOVA T, MARCHICA A, HRONCOVA Z, et al. Effects of chlorogenic acid, epicatechin gallate, and quercetin on mucin expression and secretion in the Caco-2/HT29-MTX cell model[J]. Food Sci Nutr, 2019, 7(2):492-498. [28] PI Y. Effects of different interventions on intestinal microbiota, host metabolism and gut barrier function in growing pigs[D]. Nanjing:Nanjing Agricultural University, 2019. (in Chinese) 皮宇. 不同方式干预对生长猪肠道微生物、机体代谢和肠道屏障功能的影响[D]. 南京:南京农业大学, 2019. [29] LIU H W, LI K, ZHAO J S, et al. Effects of chestnut tannins on intestinal morphology, barrier function, pro-inflammatory cytokine expression, microflora and antioxidant capacity in heat-stressed broilers[J]. J Anim Physiol Anim Nutr, 2018, 102(3):717-726. [30] SUN Y G, ZHANG X J, CHENG J, et al. Effects of two Chinese medicinal ingredients on growth performance, digestive Utilization ratios of nutrients, digestive enzyme activity and intestinal bacterial in broilers[J]. China Animal Husbandry & Veterinary Medicine, 2013, 40(4):93-98. (in Chinese) 孙耀贵, 张向杰, 程佳, 等. 2种中药成分对肉鸡生产性能、营养物质消化利用率、肠道消化酶活性和肠道菌群的影响[J]. 中国畜牧兽医, 2013, 40(4):93-98. [31] LI H L. Study on physiological and biochemical characteristics and immune function of lactic acid bacteria and tea polyphenols on broilers[D]. Changsha:Hunan Agricultural University, 2015. (in Chinese) 李华丽. 乳酸菌与茶多酚对肉鸡生理生化性能及免疫机能的研究[D]. 长沙:湖南农业大学, 2015. [32] CHENG Y, LIU Y R, CHEN D, et al. Dual effects of quercetin on protein digestion and absorption in the digestive tract[J]. Food Chem, 2021, 358:129891. [33] TONG Z K, LEI F H, LIU L X, et al. Effects of Plotytarya strohilacea sieb. et zuce tannin on the growth performance, oxidation resistance, intestinal morphology and cecal microbial composition of broilers[J]. Front Vet Sci, 2022, 8:806105. [34] DONG S, LI H, GASCO L, et al. Antioxidative activity of the polyphenols from the involucres of Castanea mollissima Blume and their mitigating effects on heat stress[J]. Poultry Sci, 2015, 94(5):1096-1104. [35] XIONG Y, DONG S, ZHAO X, et al. Gene expressions and metabolomic research on the effects of polyphenols from the involucres of Castanea mollissima Blume on heat-stressed broilers chicks[J]. Poultry Sci, 2016, 95(8):1869-1880. [36] LIU H J, WANG C, ZHOU B B, et al. Effects of dietary rutin supplementation on ileal morphology, immunity, antioxidant and barrier function of broilers[J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(2):630-641. (in Chinese) 刘慧娟, 王超, 周斌斌, 等. 饲粮中添加芦丁对肉鸡回肠形态、免疫、抗氧化及屏障功能的影响[J]. 畜牧兽医学报, 2023, 54(2):630-641. [37] WANG J. Screening of key proteins related to hepatic metabolism of weaned piglets after alfalfa saponins treatment[D]. Zhengzhou:Henan Agricultural University, 2015. (in Chinese) 王洁. 苜蓿皂苷调控断奶仔猪肝脏代谢的关键蛋白筛选[D]. 郑州:河南农业大学, 2015. [38] GAN Z D, WEI W Y, WU J M, et al. Resveratrol and curcumin improve intestinal mucosal integrity and decrease m6A RNA methylation in the intestine of weaning piglets[J]. ACS Omega, 2019, 4(17):17438-17446. [39] DOLARA P, LUCERI C, DE FILIPPO C, et al. Red wine polyphenols influence carcinogenesis, intestinal microflora, oxidative damage and gene expression profiles of colonic mucosa in F344 rats[J]. Mutat Res, 2005, 591(1-2):237-246. [40] ZHANG J Q, XIONG W, LI Z H, et al. Effects of rutin on growth, intestinal antioxidant capacity and lipid metabolism in weaned mice[J]. Journal of Nanjing Agricultural University, 2022, 45(2):368-376. (in Chinese) 张佳琦, 熊玮, 黎智华, 等. 芦丁对断奶仔鼠生长、肠道抗氧化及脂代谢的影响[J]. 南京农业大学学报, 2022, 45(2):368-376. [41] SINGH R, CHANDRASHEKHARAPPA S, BODDULURI S R, et al. Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway[J]. Nat Commun, 2019, 10(1):89. [42] HEIDEBRECHT H J, KULOZIK U. Fractionation of casein micelles and minor proteins by microfiltration in diafiltration mode. Study of the transmission and yield of the immunoglobulins IgG, IgA and IgM[J]. Int Dairy J, 2019, 93:1-10. [43] WANG Y H, BAI C X, YANG K K, et al. Mechanism of green tea powder improving intestinal barrier of immune stressed mice[J]. Acta Agriculturae Boreali-Sinica, 2019, 34(S1):136-142. (in Chinese) 王元红, 白彩霞, 杨侃侃, 等. 绿茶粉改善免疫应激小鼠肠道屏障的作用机制[J]. 华北农学报, 2019, 34(S1):136-142. [44] LU Y, LI X R, LIU S S, et al. Toll-like receptors and inflammatory bowel disease[J]. Front Immunol, 2018, 9:72. [45] SHAO X, SUN C Z, TANG X, et al. Anti-inflammatory and intestinal microbiota modulation properties of Jinxiang garlic (Allium sativum L.) polysaccharides toward dextran sodium sulfate-induced colitis[J]. J Agric Food Chem, 2020, 68(44):12295-12309. [46] NIU J H, YUAN J, WEI R, et al. Protective effect and mechanism study of jujube polysaccharides on intestinal immune barrier in mice[J]. Science and Technology of Food Industry, 2021, 42(4):295-300, 306. (in Chinese) 牛佳卉, 袁静, 魏然, 等. 红枣多糖对小鼠肠道免疫屏障的保护作用及机制研究[J]. 食品工业科技, 2021, 42(4):295-300, 306. [47] QU J L, HUANG P, ZHANG L, et al. Hepatoprotective effect of plant polysaccharides from natural resources:a review of the mechanisms and structure-activity relationship[J]. Int J Biol Macromol, 2020, 161:24-34. [48] MAO S H, FENG D D, WANG X, et al. Magnolol protects against acute gastrointestinal injury in sepsis by down-regulating regulated on activation, normal T-cell expressed and secreted[J]. World J Clin Cases, 2021, 9(34):10451-10463. [49] YE J, YE C Q, HUANG Y Y, et al. Ginkgo biloba sarcotesta polysaccharide inhibits inflammatory responses through suppressing both NF-κB and MAPK signaling pathway[J]. J Sci Food Agr, 2019, 99(5):2329-2339. [50] SUN L, XU G Q, DONG Y Y Y, et al. Quercetin protects against lipopolysaccharide-induced intestinal oxidative stress in broiler chickens through activation of nrf2 pathway[J]. Molecules, 2020, 25(5):1053. [51] MA G X, KIMATU B M, YANG W J, et al. Preparation of newly identified polysaccharide from Pleurotus eryngii and its anti-inflammation activities potential[J]. J Food Sci, 2020, 85(9):2822-2831. [52] SOKOL H. Probiotics and antibiotics in IBD[J]. Dig Dis, 2014, 32(S1):10-17. [53] KRAIMI N, LORMANT F, CALANDREAU L, et al. Microbiota and stress:a loop that impacts memory[J]. Psychoneuroendocrinology, 2022, 136:105594. [54] DING S J, JIANG H M, FANG J, et al. Regulatory effect of resveratrol on inflammation induced by lipopolysaccharides via reprograming intestinal microbes and ameliorating serum metabolism profiles[J]. Front Immunol, 2021, 12:777159. [55] LAI P K, ROY J. Antimicrobial and chemopreventive properties of herbs and spices[J]. Curr Med Chem, 2004, 11(11):1451-1460. [56] SICHERT A, CORZETT C H, SCHECHTER M S, et al. Verrucomicrobia use hundreds of enzymes to digest the algal polysaccharide fucoidan[J]. Nat Microbiol, 2020, 5(8):1026-1039. [57] LEE H C, JENNER A M, LOW C S, et al. Effect of tea phenolics and their aromatic fecal bacterial metabolites on intestinal microbiota[J]. Res Microbiol, 2006, 157(9):876-884. [58] THU T V, LOH T C, FOO H L, et al. Effects of liquid metabolite combinations produced by Lactobacillus plantarum on growth performance, faeces characteristics, intestinal morphology and diarrhoea incidence in postweaning piglets[J]. Trop Anim Health Prod, 2011, 43(1):69-75. [59] TREMAROLI V, BÄCKHED F. Functional interactions between the gut microbiota and host metabolism[J]. Nature, 2012, 489(7415):242-249. [60] MEI H D, LI Y F, TIAN Q, et al. Effects of magnolol on nutrient apparent digestibility, serum biochemical indices, main fecal microorganism numbers and their metabolite contents of weaned piglets[J]. Chinese Journal of Animal Nutrition, 2022, 34(8):4919-4931. (in Chinese) 梅华迪, 李袁飞, 田琦, 等. 厚朴酚对断奶仔猪营养物质表观消化率、血清生化指标、粪便主要微生物数量及其代谢产物含量的影响[J]. 动物营养学报, 2022, 34(8):4919-4931. |