畜牧兽医学报 ›› 2021, Vol. 52 ›› Issue (5): 1171-1185.doi: 10.11843/j.issn.0366-6964.2021.05.004
郭蓉, 郭亚洲, 王帅, 杨晨, 苏永霞, 吴晨晨, 路浩, 赵宝玉*
收稿日期:
2020-10-06
出版日期:
2021-05-23
发布日期:
2021-05-22
通讯作者:
赵宝玉,主要从事动物有毒植物中毒病致病机理与防控研究,E-mail:Zhaobaoyu12005@163.com
作者简介:
郭蓉(1995-),女,陕西汉中人,硕士,主要从事动物中毒病与毒理学研究,E-mail:guorongnw1995@163.com
基金资助:
GUO Rong, GUO Yazhou, WANG Shuai, YANG Chen, SU Yongxia, WU Chenchen, LU Hao, ZHAO Baoyu*
Received:
2020-10-06
Online:
2021-05-23
Published:
2021-05-22
摘要: 中国是世界草地资源大国,天然草地作为我国面积最大的陆地生态系统和重要的绿色生态屏障,具有多种生态功能,同时也是发展草地畜牧业的重要基地和牧民最基本的生产生活资料。但长期以来,人们只重视天然草地的生产功能,而忽视了对天然草地生态系统的保护,使得我国天然草地长期处于过度利用状态,造成草地退化,进一步引发有毒植物等生物灾害多发、频发,可食牧草种类和产量锐减,生物多样性失调及生态环境恶化。本文简要概述了我国天然草地有毒植物的种类与分布,介绍了有毒植物给目前我国天然草地以及畜牧业带来的经济损失以及危害,针对疯草类有毒植物、乌头属有毒植物、橐吾属有毒植物、瑞香狼毒、醉马芨芨草、紫茎泽兰6种危害较为严重的有毒植物的毒理学与中毒病及其防治技术方面的研究进展作了概述,对未来在有毒植物中毒的防控方面提出几点建议,旨在为我国草原牧区放牧家畜有毒植物中毒病综合防控和健康养殖提供理论指导。
中图分类号:
郭蓉, 郭亚洲, 王帅, 杨晨, 苏永霞, 吴晨晨, 路浩, 赵宝玉. 中国天然草地有毒植物及其放牧家畜中毒病研究进展[J]. 畜牧兽医学报, 2021, 52(5): 1171-1185.
GUO Rong, GUO Yazhou, WANG Shuai, YANG Chen, SU Yongxia, WU Chenchen, LU Hao, ZHAO Baoyu. Advances in Research on Poisonous Plants and Grazing Livestock Poisoning Diseases of Natural Grassland in China[J]. Acta Veterinaria et Zootechnica Sinica, 2021, 52(5): 1171-1185.
[1] | 刘源. 2016年全国草原监测报告[J]. 中国畜牧业, 2017(8):18-35.LIU Y. National grassland monitoring report in 2016[J]. China Animal Industry, 2017(8):18-35. (in Chinese) |
[2] | 张一诺苑铁军. 草原,美丽中国的绿色基石[N/OL]. 中国绿色时报, 2019-03-05(6)[2021-03-02]. http://www.greentimes.com/greentimepaper/html/2019-03/05/content_3331044.htm. ZHANG Y N, YUAN T J. Grassland, the green cornerstone of beautiful China [N/OL]. China Green Times, 2019-03-05(6)[2021-03-02]. http://www.greentimes.com/greentimepaper/html/2019-03/05/content_3331044.htm. |
[3] | 霍延卫, 鱼海燕. 新时代草原保护的新策略[J]. 现代畜牧科技, 2020(9):16-17.HUO Y W, YU H Y. New strategies for grassland protection in the new era[J]. Modern Animal Husbandry Science & Technology, 2020(9):16-17. (in Chinese) |
[4] | 沈海花, 朱言坤, 赵霞, 等. 中国草地资源的现状分析[J]. 科学通报, 2016, 61(2):139-154.SHEN H H, ZHU Y K, ZHAO X, et al. Analysis of current grassland resources in China[J]. Chinese Science Bulletin, 2016, 61(2):139-154. (in Chinese) |
[5] | 赵宝玉, 刘忠艳, 万学攀, 等. 中国西部草地毒草危害及治理对策[J]. 中国农业科学, 2008(10):3094-3103.ZHAO B Y, LIU Z Y, WAN X P, et al. Damage and control of poisonous-weeds in Chinese western grassland[J]. Scientia Agricultura Sinica, 2008(10):3094-3103. (in Chinese) |
[6] | 赵宝玉, 尉亚辉, 魏朔南, 等. 我国天然草原毒害草灾害与防控策略[C]//2015中国草原论坛. 锡林浩特:中国草学会, 2015:217-232.ZHAO B Y, WEI Y H, WEI S N, et al. The species, geographical distribution, disaster and control measures of poisonous weeds in natural grasslands of China[C]//Proceedings of 2015 China Grassland Forum Proceedings. Xilinhot: Chinese herbaceous Society, 2015:217-232. (in Chinese) |
[7] | 赵宝玉, 莫重辉. 天然草原牲畜毒害草中毒防治技术[M]. 杨凌:西北农林科技大学出版社, 2017.ZHAO B Y, MO C H. Prevention and control technique on poisonous weeds poisoning of livestock in natural grassland[M]. Yangling: Northwest A&F University Press, 2017. (in Chinese) |
[8] | 尉亚辉, 赵宝玉, 魏朔南, 等. 中国西部天然草地毒害草的主要种类及分布[M]. 北京:科学出版社, 2018.WEI Y H, ZHAO B Y, WEI S N, et al. Main species and distribution of poisonous weeds in natural grassland in western China[M]. Beijing: Science Press, 2018. (in Chinese) |
[9] | ZHAO B Y. The disaster and toxicant mechanisms and prevention and control of locoweed in Western China[C]//Proceedings of the 10th International Symposium on Poisonous Plants. 2018. |
[10] | 尉亚辉, 赵宝玉, 达能太, 等. 草原主要毒害草研究策略与进展[C]//2015中国草原论坛. 锡林浩特:中国草学会, 2015:199-216.WEI Y H, ZHAO B Y, DA N T, et al. Research strategy and progress of main poisonous weeds in grassland[C]//Proceedings of 2015 China Grassland Forum Proceedings. Xilinhot:Chinese Herbaceous Society, 2015:199-216. (in Chinese) |
[11] | MOLYNEUX R J. Analysis and distribution of swainsonine and related polyhydroxyindolizidine alkaloids by thin layer chromatography[J]. Phytochem Anal, 1991, 2(3):125-129. |
[12] | 高新磊, 韩冰, 赵萌莉, 等. 疯草及毒性成分研究进展[J]. 草业学报, 2011, 20(3):279-286.GAO X L, HAN B, ZHAO M L, et al. Locoweed and advances in research on toxic components[J]. Acta Prataculturae Sinica, 2011, 20(3):279-286. (in Chinese) |
[13] | 赵宝玉, 王保海, 莫重辉, 等. 西藏阿里地区牲畜冰川棘豆中毒灾害状况调查[J]. 西北农业学报, 2011, 20(4):40-46.ZHAO B Y, WANG B H, MO C H, et al. The disaster survey of the Oxytropis glacialis poisoning in livestock in the Ngari of Tibet[J]. Acta Agriculturae Boreali-occidentalis Sinica, 2011, 20(4):40-46. (in Chinese) |
[14] | 周启武, 赵宝玉, 路浩, 等. 中国西部天然草地疯草生态及动物疯草中毒研究与防控现状[J]. 中国农业科学, 2013, 46(6):1280-1296.ZHOU Q W, ZHAO B Y, LU H, et al. The research and control situation of ecology and animal poisoning of locoweed in Western natural grassland of China[J]. Scientia Agricultura Sinica, 2013, 46(6):1280-1296. (in Chinese) |
[15] | COLEGATE S M, DORLING P R, HUXTABLE C R. A spectroscopic investigation of swainsonine:an α-mannosidase inhibitor isolated from Swainsona canescens[J]. Aust J Chem, 1979, 32(10):2257-2264. |
[16] | TULSIANI D R P, BROQUIST H P, JAMES L F, et al. The similar effects of swainsonine and locoweed on tissue glycosidases and oligosaccharides of the pig indicate that the alkaloid is the principal toxin responsible for the induction of locoism[J]. Arch Biochem Biophys, 1984, 232(1):76-85. |
[17] | DORLING P R, COLEGATE S M, HUXTABLE C R. Toxic species of the plant genus swainsona[M]//JAMES L F, ELBEIN A D, MOLYNEUX R J, et al. Swainsonine and Related Glycosidase Inhibitors. Ames, IA:Iowa State University Press, 1989:14-22. |
[18] | 赵宝玉, 曹光荣, 李绍君. 劲直黄芪有毒成分的分离与鉴定[J]. 中国兽医科技, 1993(9):20-21.ZHAO B Y, CAO G R, LI S J. Separation and identification of posionous components of Astragalus strictus[J]. Chinese Veterinary Science, 1993(9):20-21. (in Chinese) |
[19] | 李勤凡, 王建华, 李蓉, 等. 冰川棘豆生物碱分析及苦马豆素的分离、鉴定[J]. 畜牧兽医学报, 2005, 36(12):1339-1343.LI Q F, WANG J H, LI R, et al. Detection of alkaloid and isolation of swainsonine from Oxytropis glacialis[J]. Acta Veterinaria et Zootechnica Sinica, 2005, 36(12):1339-1343. (in Chinese) |
[20] | 梁妍, 宋向东, 谢宗秀, 等. 疯草内生真菌研究进展[J]. 动物医学进展, 2020, 41(9):106-110.LIANG Y, SONG X D, XIE Z X, et al. Progress on endophytic fungi in locoweed[J]. Progress in Veterinary Medicine, 2020, 41(9):106-110. (in Chinese) |
[21] | 郝宝成, 梁剑平, 杨贤鹏, 等. “疯草”中苦马豆素解毒制剂及抗肿瘤应用研究进展[J]. 安徽农业科学, 2012, 40(5):2664-2665, 2668.HAO B C, LIANG J P, YANG X P, et al. Research advances in the detoxificating preparation of swainsonine in “Locoweed” and its application to anti-tumor[J]. Journal of Anhui Agricultural Sciences, 2012, 40(5):2664-2665, 2668. (in Chinese) |
[22] | 余永涛, 刘志滨, 赵兴华, 等. 毛瓣棘豆中苦马豆素的纯化与鉴定[J]. 畜牧与兽医, 2006, 38(5):1-3.YU Y T, LIU Z B, ZHAO X H, et al. Purification and identification of swainsonine in the Oxytropis. serioopetala C. R. C. Fisch[J]. Animal Husbandry & Veterinary Medicine, 2006, 38(5):1-3. (in Chinese) |
[23] | WU C C, YAN D J, LU D Z, et al. Alteration of the PI3K/Akt signaling pathway by swainsonine affects 17β-Estradiol secretion in ovary cells[J]. Theriogenology, 2017, 103:123-129. |
[24] | 浮晶晶, 郭亚洲, 黄文颖, 等. 疯草类植物在美国天然草地的分布及其动物中毒病研究现状与展望[J]. 草地学报, 2019, 27(3):519-530.FU J J, GUO Y Z, HUANG W Y, et al. The distribution of locoweed in natural grassland in the United States and the current status and prospects of research on animal poisoning[J]. Acta Agrestia Sinica, 2019, 27(3):519-530. (in Chinese) |
[25] | WU C C, WANG W L, LIU X X, et al. Pathogenesis and preventive treatment for animal disease due to locoweed poisoning[J]. Environ Toxicol Pharmacol, 2014, 37(1):336-347. |
[26] | 王毅, 彭铭, 高欣, 等. 苦马豆素致糖基转移酶活性改变对小鼠生殖激素分泌的影响[J]. 生态毒理学报, 2019, 14(3):174-185.WANG Y, PENG M, GAO X, et al. Swainsonine poisoning-induced changes of glycosyltransferase activity affected secretion of reproductive hormone in mice[J]. Asian Journal of Ecotoxicology, 2019, 14(3):174-185. (in Chinese) |
[27] | 刘建枝, 赵宝玉, 王保海. 中国西部天然草地疯草概论[M]. 北京:科学出版社, 2018.LIU J Z, ZHAO B Y, WANG B H. Introduction to natural grasslandlocoweed in western China[M]. Beijing:Science Press, 2018. (in Chinese) |
[28] | 王庆海, 李翠, 庞卓, 等. 中国草地主要有毒植物及其防控技术[J]. 草地学报, 2013, 21(5):831-841.WANG Q H, LI C, PANG Z, et al. Poisonous weeds in Chinese grassland and control technology[J]. Acta Agrectir Sinica, 2013, 21(5):831-841. (in Chinese) |
[29] | 严杜建, 周启武, 路浩, 等. 新疆天然草地毒草灾害分布与防控对策[J]. 中国农业科学, 2015, 48(3):565-582.YAN D J, ZHOU Q W, LU H, et al. The disaster, ecological distribution and control of poisonous weeds in natural grasslands of Xinjiang Uygur autonomous region[J]. Scientia Agricultura Sinica, 2015, 48(3):565-582. (in Chinese) |
[30] | 李宏, 陈卫民, 陈翔, 等. 新疆伊犁草原毒害草种类及其发生与危害[J]. 草业科学, 2010, 27(11):171-173.LI H, CHEN W M, CHEN X, et al. Poisonous weed species and their harmfulness in the grassland of Yili regions, Xinjiang Uygur autonomous region of China[J]. Pratacultural Science, 2010, 27(11):171-173. (in Chinese) |
[31] | 安沙舟, 李宏, 李学贤, 等. 新疆伊犁河谷天然草地毒害草种类分布及防治对策[J]. 新疆农业科学, 2010, 47(3):540-542.AN S Z, LI H, LI X X, et al. Distribution of poisonous and harm plants and their prevention countermeasure in Ili river valley, Xinjiang[J]. Xinjiang Agricultural Sciences, 2010, 47(3):540-542. (in Chinese) |
[32] | 王守宝, 龚宁波, 段昌令, 等. 乌头类中药毒的历史认识与现代研究[J]. 中药药理与临床, 2019, 35(2):149-151.WANG S B, GONG N B, DUAN C L, et al. Historical cognition and modern evaluation on the toxicity of Aconitum-derived Chinese traditional medicines[J]. Pharmacology and Clinics of Chinese Materia Medica, 2019, 35(2):149-151. (in Chinese) |
[33] | 刘艳, 章诗伟, 周兰, 等. 乌头类生物碱对心肌的毒性作用及分子毒理学研究进展[J]. 中国法医学杂志, 2009, 24(6):398-401.LIU Y, ZHANG S W, ZHOU L, et al. The toxicity of aconitum alkaloids on cardiocytes and the progress of its research using the methods of molecular toxicology[J]. Chinese Journal of Forensic Medicine, 2009, 24(6):398-401. (in Chinese) |
[34] | 翟金俊. 乌头碱类中药中毒22例临床分析[J]. 山西职工医学院学报, 2011, 21(1):50-51.ZHAI J J. Clinical analysis of 22 cases of aconitine poisoning by traditional Chinese medicine[J]. Journal of Shanxi Health Vocational College, 2011, 21(1):50-51. (in Chinese) |
[35] | 雷怀成, 易建华. 乌头碱中毒肾小管上皮细胞凋亡的观察[J]. 工业卫生与职业病, 2005, 31(2):83-85.LEI H C, YI J H. Observation of apoptosis in renal tubule epithelial cell after aconitine poisoning[J]. Industrial Health and Occupational Diseases, 2005, 31(2):83-85. (in Chinese) |
[36] | 杨琳. 新疆阿勒泰地区天然草地毒害草种群分布与危害及防控调查[D]. 杨凌:西北农林科技大学, 2019.YANG L. Investigation on population distribution, harm and control of poisonous grass on natural grassland in Altay region of Xinjiang[D]. Yangling:Northwest A&F University, 2019. (in Chinese) |
[37] | 何静, 余马, 舒晓燕, 等. 乌头花叶病病原物的分子鉴定[J]. 中国农学通报, 2018, 34(25):26-31.HE J, YU M, SHU X Y, et al. Pathogen molecular identification of mosaic disease Aconitum[J]. Chinese Agricultural Science Bulletin, 2018, 34(25):26-31. (in Chinese) |
[38] | 赵德良. 新疆新源县草原毒害草种类及防治措施[J]. 草食家畜, 2014(2):42-49.ZHAO D L. Prevention measures species of poisonous-weeds in Xinyuan Xinjiang[J]. Grass-Feeding Livestock, 2014(2):42-49. (in Chinese) |
[39] | 陈卫民, 王杰花, 荆珺. 氯氨吡啶类除草剂不同浓度对草原毒草-准噶尔乌头防效及安全性评价[C]//第十二届全国杂草科学大会论文摘要集. 太原:中国植物保护学会杂草学分会, 2015:109-115.CHEN W M, WANG J H, JING J. Aminopyralid herbicide different concentrations for grassland poisonous weeds Junggar Aconitum control effect and safety evaluation[C]//Proceedings of the Collection of Abstracts of the 12th National Weed Science Conference. Taiyuan:Weed Science Society of China CSPP, 2015:109-115. (in Chinese) |
[40] | 贾晓光, 周琴, 王果平, 等. 乌头草中毒症状及临床解救[J]. 新疆中医药, 2012, 30(3):67-70.JIA X G, ZHOU Q, WANG G P, et al. Aconitum poisoning symptoms and clinical rescue[J]. Xinjiang Journal of Traditional Chinese Medicine, 2012, 30(3):67-70. (in Chinese) |
[41] | 张舒涵, 李晋奇. 乌头碱心脏毒性作用机制的研究进展[J]. 中西医结合心脑血管病杂志, 2018, 16(10):1366-1370.ZHANG S H, LI J Q. Research progress on the mechanism of aconitine cardiotoxicity[J]. Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease, 2018, 16(10):1366-1370. (in Chinese) |
[42] | 郭亚洲, 张睿涵, 孙暾, 等. 甘肃天然草地毒草危害、防控与综合利用[J]. 草地学报, 2017, 25(2):243-256.GUO Y Z, ZHANG R H, SUN T, et al. Harm, control and comprehensive utilization of poisonous weeds in natural grasslands of Gansu province[J]. Acta Agrestia Sinica, 2017, 25(2):243-256. (in Chinese) |
[43] | 黄立铭. 黄南州天然草地毒草调查与防治[J]. 四川草原, 2006(5):24-26, 32.HUANG L M. Investigation and control of poisonous weeds in natural grassland in Huangnan Prefecture[J]. Journal of Sichuan Grassland, 2006(5):24-26, 32. (in Chinese) |
[44] | 田苗, 王秀茹, 李国利, 等. 橐吾属植物化学成分的研究展望[J]. 广州化工, 2011, 39(15):37-42.TIAN M, WANG X R, LI G L, et al. Study on the chemical ingredients from the ligularia plant[J]. Guangzhou Chemical Industry and Technology, 2011, 39(15):37-42. (in Chinese) |
[45] | 王君, 皇甫玉飞, 高晓航. 橐吾属植物药理作用的研究进展[J]. 求医问药, 2012, 10(2):269-270.WANG J, HUANGFU Y F, GAO X H. Research progress on the pharmacological action of Ligularia plant[J]. Seek Medical and Ask the Medicine, 2012, 10(2):269-270. (in Chinese) |
[46] | 王涛, 宋海波. 吡咯里西啶类生物碱肝毒性研究进展及风险分析[J]. 医药导报, 2018, 37(9):1033-1037.WANG T, SONG H B. Research progress and risk analysis on hepatotoxicity of pyrrolizidine alkaloids[J]. Herald of Medicine, 2018, 37(9):1033-1037. (in Chinese) |
[47] | 韩佳寅, 梁爱华, 高双荣. 含吡咯里西啶生物碱植物的特殊毒性及致毒机制研究进展[J]. 中国中药杂志, 2011, 36(10):1397-1401.HAN J Y, LIANG A H, GAO S R. Research progress of especial toxicity and of pyrrolizidine alkaloids[J]. China Journal of Chinese Materia Medica, 2011, 36(10):1397-1401. (in Chinese) |
[48] | LIU X Q, LIN G, WANG G J, et al. Metabolism of clivorine in female rat liver microsomes[J]. Chinese Journal of Pharmacology and Toxicology, 2001, 15(6):413-417. |
[49] | LIU X Q, LIN G, WANG G J, et al. Involvement of human CYP3A4 in the formation of hepatotoxic metabolites of clivorine[J]. Chinese Journal of Pharmacology and Toxicology, 2002, 16(1):15-20. |
[50] | 张凯, 董晓敏, 王琦, 等. 常用中药肝毒性成分代谢与毒理研究进展[J]. 中草药, 2018, 49(22):5435-5447.ZHANG K, DONG X M, WANG Q, et al. Research progress on metabolism and toxicology of hepatotoxic components in common Chinese materia medica[J]. Chinese Traditional and Herbal Drugs, 2018, 49(22):5435-5447. (in Chinese) |
[51] | 林永明. 牛羊黄帚橐吾草中毒症的诊治[J]. 中国草食动物, 2011, 31(3):74-75.LIN Y M. Diagnosis and treatment of Ligularia virgaurea poisoning in cattle and goat[J]. China Herbivores, 2011, 31(3):74-75. (in Chinese) |
[52] | 马寿福, 邓君, 刁治民, 等. 青海省狼毒研究现状、综合利用及防治[J]. 青海草业, 2007, 16(1):17-21.MA S F, DENG J, DIAO Z M, et al. Present research situation, comprehensive utilization and control countermeasures of Stellera chamaejasme L. in Qinghai[J]. Qinghai Prataculture, 2007, 16(1):17-21. (in Chinese) |
[53] | 王欢, 马青成, 耿朋帅, 等. 天然草地瑞香狼毒研究进展[J]. 动物医学进展, 2015, 36(12):154-160.WANG H, MA Q C, GENG P S, et al. Progress on Stellera chamaejasme in natural grasslands[J]. Progress in Veterinary Medicine, 2015, 36(12):154-160. (in Chinese) |
[54] | 王兴桂, 莫重辉. 绵羊瑞香狼毒中毒病理组织学观察[J]. 动物医学进展, 2018, 39(10):126-129.WANG X G, MO C H. Histopathological observations on sheep poisoning of Stellera chamaejasme[J]. Progress in Veterinary Medicine, 2018, 39(10):126-129. (in Chinese) |
[55] | 黄弥娜, 曹青青, 李云青, 等. 瑞香狼毒毒性部位的化学成分研究[J]. 环球中医药, 2016, 9(9):1059-1064.HUANG M N, CAO Q Q, LI Y Q, et al. Study on chemical constituents of toxicity parts in Stellera chamaejasme L. [J]. Global Traditional Chinese Medicine, 2016, 9(9):1059-1064. (in Chinese) |
[56] | 李云青. 瑞香狼毒毒性物质基础研究[D]. 上海:第二军医大学, 2016.LI Y Q. Study on toxic constituents of Stellera chamaejasme L. [D]. Shanghai:The Secondary Military Medical University, 2016. (in Chinese) |
[57] | 薄彧坤, 周燕, 王伟, 等. 瑞香狼毒药材中蛋白质部位的体外活性研究[J]. 时珍国医国药, 2010, 21(9):2262-2264.BO Y K, ZHOU Y, WANG W, et al. Study on in vitro activity of protein site from Stellera chamaejasme L. [J]. Lishizhen Medicine and Materia Medica Research, 2010, 21(9):2262-2264. (in Chinese) |
[58] | 韩波, 屈萌, 马晓莉, 等. 狼毒毒性和炮制方法研究进展[J]. 中药材, 2013, 36(2):330-333.HAN B, QU M, MA X L, et al. Research progress in toxicity and processing methods of Stellera chamaejasme[J]. Journal of Chinese Medicinal Materials, 2013, 36(2):330-333. (in Chinese) |
[59] | 纪亚君. 醉马芨芨草的研究进展[J]. 安徽农业科学, 2009, 37(5):2154-2156, 2169.JI Y J. Research progress on Achnatherum inebrians[J]. Journal of Anhui Agricultural Sciences, 2009, 37(5):2154-2156, 2169. (in Chinese) |
[60] | 李春杰, 南志标, 张昌吉, 等. 醉马草内生真菌对家兔的影响[J]. 中国农业科技导报, 2009, 11(2):84-90.LI C J, NAN Z B, ZHANG C J, et al. Effects of drunken horse grass infected with endophyte on Chinese rabbit[J]. Journal of Agricultural Science and Technology, 2009, 11(2):84-90. (in Chinese) |
[61] | 张伟, 李冠. 醉马草化学成分预试及毒性部位筛选[J]. 动物医学进展, 2006, 27(7):97-99.ZHANG W, LI G. Toxic components and sections screened out from fragments extracted from Achnatherum inebrians[J]. Progress in Veterinary Medicine, 2006, 27(7):97-99. (in Chinese) |
[62] | 张睿涵, 郭亚洲, 达能太, 等. 天然草地醉马芨芨草分布、毒性及防治利用研究进展[J]. 中国草地学报, 2017, 39(3):96-102.ZHANG R H, GUO Y Z, DA N T, et al. Research progress in distribution, poisoning, prevention and control and utilization of Achnatherum inebrians in natrual grassland[J]. Chinese Journal of Grassland, 2017, 39(3):96-102. (in Chinese) |
[63] | 靳瑰丽, 朱习雯, 魏秀红, 等. 不同方法对醉马草防控效果的比较[J]. 草地学报, 2017, 25(3):625-632.JIN G L, ZHU X W, WEI X H, et al. Effects of different control methods on Achnatherum inebrians[J]. Acta Agrestia Sinica, 2017, 25(3):625-632. (in Chinese) |
[64] | 朱习雯, 靳瑰丽, 万江春, 等. 发酵抑制剂对青贮醉马芨芨草脱毒效果的影响评价[J]. 中国草地学报, 2017, 39(3):83-89.ZHU X W, JIN G L, WAN J C, et al. Evaluation of the detoxification effect of fermentation inhibitors on Achnatherum inebrians silage[J]. Chinese Journal of Grassland, 2017, 39(3):83-89. (in Chinese) |
[65] | 周启武, 于龙凤, 王绍梅, 等. 入侵植物紫茎泽兰的危害及综合防控与利用[J]. 动物医学进展, 2014, 35(5):108-113.ZHOU Q W, YU L F, WANG S M, et al. Harm, comprehensive control and utilization of invasion plant E. adenophorum[J]. Progress in Veterinary Medicine, 2014, 35(5):108-113. (in Chinese) |
[66] | 鲁萍, 桑卫国, 马克平. 外来入侵种紫茎泽兰研究进展与展望[J]. 植物生态学报, 2005, 29(6):1029-1037.LU P, SANG W G, MA K P. Progress and prospects in research of an exotic invasive species, Eupatorium adenophorum[J]. Acta Phytoecologica Sinica, 2005, 29(6):1029-1037. (in Chinese) |
[67] | 白洁. 外来入侵植物紫茎泽兰毒性物质基础研究[D]. 北京:中国农业科学院(北京), 2012.BAI J. The foundational studies of toxicity substances in exotic invasive plant Eupatorium adenophorum Spreng[D]. Beijing:Chinese Academy of Agricultural Sciences (Beijing), 2012. (in Chinese) |
[68] | 董强, 赵宝玉, 顾强, 等. 紫茎泽兰全草对小鼠毒性试验[J]. 西北大学学报:自然科学版, 2011, 41(3):469-472.DONG Q, ZHAO B Y, GU Q, et al. Toxicity test of Eupatorium adenophorum spreng on mice[J]. Journal of Northwest University:Natural Science Edition, 2011, 41(3):469-472. (in Chinese) |
[69] | 叶妍琳, 扬子江, 付偲, 等. 紫茎泽兰对马肝肾功能的影响[J]. 中兽医医药杂志, 2016, 35(4):47-48.YE Y L, YANG Z J, FU S, et al. Effects of Euratorium adenophorum Spreng on horse liver and kidney[J]. Journal of Traditional Chinese Veterinary Medicine, 2016, 35(4):47-48. (in Chinese) |
[70] | 符杰, 胡延春, 陈伟红, 等. 紫茎泽兰对萨能奶山羊血常规及重要脏器病理学的影响[J]. 草业科学, 2018, 35(2):434-440.FU J, HU Y C, CHEN W H, et al. Dosage-dependent effects of Eupatorium adenophorum on Saanen goat blood levels and the histopathology of several organs[J]. Pratacultural Science, 2018, 35(2):434-440. (in Chinese) |
[71] | 李超, 李厚勇, 张振铃, 等. 紫茎泽兰提取物对小鼠免疫毒性的研究[J]. 毒理学杂志, 2015, 29(3):190-192.LI C, LI H Y, ZHANG Z L, et al. Study on the immunotoxicity of Eupatorium adenophorum extracts in mice[J]. Journal of Toxicology, 2015, 29(3):190-192. (in Chinese) |
[72] | SUN W, ZENG C R, YUE D, et al. Involvement of mitochondrial dysfunction in hepatotoxicity induced by Ageratina adenophora in mice[J]. J Zhejiang Univ-Sci B, 2019, 20(8):693-698. |
[73] | 李丽萍, 杨明嘉, 谢响明. 紫茎泽兰的微生物防治研究进展[J]. 中国农学通报, 2008, 24(5):348-350.LI L P, YANG M J, XIE X M. Prowess on the microbiological control of Eupatorium coelestinum[J]. Chinese Agricultural Science Bulletin, 2008, 24(5):348-350. (in Chinese) |
[74] | 李霞霞, 张钦弟, 朱珣之. 近十年入侵植物紫茎泽兰研究进展[J]. 草业科学, 2017, 34(2):283-292.LI X X, ZHANG Q D, ZHU X Z. Progress of the research on invasive plant species Eupatorium adenophorum over the last decade[J]. Pratacultural Science, 2017, 34(2):283-292. (in Chinese) |
[75] | 崔昌华, 李扬, 朱朝华. 紫茎泽兰入侵机制及防治方法的研究进展[J]. 安徽农业科学, 2009, 37(20):9532-9534.CUI C H, LI Y, ZHU C H. Research development of invasion mechanisms and control method of Eupatorium adenophorum[J]. Journal of Anhui Agricultural Sciences, 2009, 37(20):9532-9534. (in Chinese) |
[76] | 尹芳, 黄梅, 徐锐, 等. 紫茎泽兰的危害及其综合利用进展分析[J]. 灾害学, 2009, 24(4):63-67.YIN F, HAUNG M, XU R, et al. Analysis on eupatorium hazards and development in its comprehensive utilization[J]. Journal of Catastrophology, 2009, 24(4):63-67. (in Chinese) |
[77] | 娄予强, 黄健, 陆自芹, 等. 入侵植物紫茎泽兰的开发利用[J]. 广西热带农业, 2008(5):21-23.LOU Y Q, HUANG J, LU Z Q, et al. The Development and utilization of exotic plant Eupatorium adenophorurn Spreng[J]. Guangxi Tropical Agriculture, 2008(5):21-23. (in Chinese) |
[1] | 曹晋康, 张纯, 王佳瑶, 李晓彤, 王鹏宇, 方颖妍, 张昱, 丁宁, 姜力. 中国荷斯坦公牛不同耐冻性精子的蛋白质组学分析[J]. 畜牧兽医学报, 2024, 55(3): 1052-1061. |
[2] | 王振宇, 张赛博, 刘文慧, 梁栋, 任小丽, 闫磊, 闫跃飞, 高腾云, 张震, 黄河天. 基于SNP芯片数据分析不同奶牛场基因组近交系数及筛选功能性基因[J]. 畜牧兽医学报, 2023, 54(7): 2848-2857. |
[3] | 高超群, 曹然然, 杜文苹, 胡晓玉, 雷艳茹, 李文婷, 康相涛. 基于全基因组SNP标记分析中国地方鸡品种的遗传多样性和种群结构[J]. 畜牧兽医学报, 2023, 54(2): 554-562. |
[4] | 孙东晓, 张胜利, 张勤, 李姣, 张桂香, 刘丑生, 郑伟杰. 我国奶牛基因组选择技术应用进展[J]. 畜牧兽医学报, 2023, 54(10): 4028-4039. |
[5] | 杨洋, 周子薇, 张京一, 杨硕, 王博宇, 葛楠, 林叶, 侯晓明. 奶牛SP1基因结构及对乳脂合成功能的初步分析[J]. 畜牧兽医学报, 2022, 53(9): 2970-2981. |
[6] | 宋月通, 张汝美, 李彦芹, 李荣岭, 高运东, 仲跻峰, 薛光辉, 王玉东, 李建斌, 孙东晓. 山东省荷斯坦奶牛体型性状遗传参数估计及系谱世代数的影响[J]. 畜牧兽医学报, 2022, 53(5): 1384-1395. |
[7] | 刘佳敏, 禹保军, 母童, 张迪, 冯小芳, 张娟, 王影, 温万, 顾亚玲. 奶牛乳脂代谢关键miRNAs的筛选及鉴定[J]. 畜牧兽医学报, 2022, 53(12): 4244-4257. |
[8] | 苏丁然, 彭朋, 闫青霞, 陈绍祜, 张胜利, 李姣, 刘丑生, 孙东晓. 我国荷斯坦青年公牛基因组选择效果分析[J]. 畜牧兽医学报, 2021, 52(6): 1550-1562. |
[9] | 周姵诺, 蔡文涛, 陈燕, 张路培, 徐凌洋, 高雪, 高会江, 王泽昭, 朱波, 李俊雅. 中国肉用西门塔尔牛场间遗传联系分析[J]. 畜牧兽医学报, 2021, 52(6): 1563-1570. |
[10] | 陈紫薇, 师睿, 罗汉鹏, 田佳, 魏趁, 张伟新, 李委奇, 温万, 王雅晶, 王雅春. 宁夏地区荷斯坦牛青年牛繁殖性状遗传参数估计[J]. 畜牧兽医学报, 2021, 52(2): 344-351. |
[11] | 彭朋, 李建明, 蒋桂娥, 杨晨东, 马亚宾, 倪俊卿, 孙东晓. 河北省中国荷斯坦牛产奶和体型性状遗传参数分析[J]. 畜牧兽医学报, 2021, 52(1): 42-51. |
[12] | 朱波, 李姣, 汪聪勇, 徐凌洋, 陈燕, 高雪, 张路培, 高会江, 李俊雅. 我国肉用西门塔尔牛群体生长发育性状遗传参数估计及其遗传进展[J]. 畜牧兽医学报, 2020, 51(8): 1833-1844. |
[13] | 魏趁, 关鸣轩, 付雪峰, 田月珍, 徐新明, 哈尼克孜·吐拉甫, 黄锡霞, 王雅春, 田可川, 王志明, 鲁兰·哈依尔别. 运用贝叶斯方法估计中国美利奴羊(新疆型)毛用性状及繁殖性状的遗传参数[J]. 畜牧兽医学报, 2020, 51(7): 1537-1547. |
[14] | 李帅, 纪晓霞, 杨博, 许濛, 张源淑. 中国麻鸭血管紧张素转化酶2(ACE2)的基因克隆及基因结构的序列解析[J]. 畜牧兽医学报, 2020, 51(7): 1597-1606. |
[15] | 欧爱群, 王凯, 吴黎明, 李江红, 彭文君. 蜂胶对细菌脂多糖刺激下奶牛乳腺上皮细胞炎症相关基因mRNA转录水平和紧密连接蛋白的影响[J]. 畜牧兽医学报, 2020, 51(5): 1149-1157. |
阅读次数 | ||||||
全文 |
|
|||||
摘要 |
|
|||||