畜牧兽医学报 ›› 2021, Vol. 52 ›› Issue (10): 2687-2697.doi: 10.11843/j.issn.0366-6964.2021.010.001
张海亮1, 常瑶1, 娄文琦1, 王凯1, 陈紫薇1, 米思远1, 温万2, 王雅春1*
收稿日期:
2021-01-21
出版日期:
2021-10-23
发布日期:
2021-10-27
通讯作者:
王雅春,主要从事分子数量遗传学研究,E-mail:wangyachun@cau.edu.cn
作者简介:
张海亮(1995-),男,甘肃甘谷人,博士生,主要从事分子数量遗传学研究,E-mail:zhl108@cau.edu.cn
基金资助:
ZHANG Hailiang1, CHANG Yao1, LOU Wenqi1, WANG Kai1, CHEN Ziwei1, MI Siyuan1, WEN Wan2, WANG Yachun1*
Received:
2021-01-21
Online:
2021-10-23
Published:
2021-10-27
摘要: 各国奶牛群体的选育目标建立之后,选育目标一直在不断发展,选择指数中性状的组成、定义和权重等都在不断变化。奶牛的选育是从关注产奶性能而开始,随后增加了体型外貌性状。由于奶牛的健康和繁殖问题的增加以及社会对动物福利的不断关注,20世纪末,世界范围内平衡育种理念在奶牛育种中逐渐形成,一些重要的功能性状加入各国的选择指数中;进入21世纪后,随着奶牛养殖业和社会的发展,育种家们开始关注和研究更多的性状,部分新性状已经开始在育种实践中选育应用。本文通过整理奶牛育种中有关新性状的研究并收集各国奶牛选育方案中的相关信息,综述了近十年奶业发达国家在奶牛遗传选育中正在研究或已经开始应用的新性状,并将这些新性状分为生产效率相关的新性状、应对环境挑战的新性状、健康福利相关的新性状、产品和加工相关的新性状及管理相关的新性状五大类,总结了这些性状的选育背景、定义方法、遗传基础和选育应用情况等,最后还总结了奶牛育种中新性状的研究应用过程,以期为我国奶牛遗传育种研究和育种目标完善提供一定的借鉴。
中图分类号:
张海亮, 常瑶, 娄文琦, 王凯, 陈紫薇, 米思远, 温万, 王雅春. 奶牛育种中关注的新性状[J]. 畜牧兽医学报, 2021, 52(10): 2687-2697.
ZHANG Hailiang, CHANG Yao, LOU Wenqi, WANG Kai, CHEN Ziwei, MI Siyuan, WEN Wan, WANG Yachun. A Review on Novel Traits in Dairy Cattle Breeding[J]. Acta Veterinaria et Zootechnica Sinica, 2021, 52(10): 2687-2697.
[1] | MIGLIOR F,FLEMING A,MALCHIODI F,et al.A 100-Year Review:identification and genetic selection of economically important traits in dairy cattle[J].J Dairy Sci,2017,100(12):10251-10271. |
[2] | GARCÍA-RUIZ A,COLE J B,VANRADEN P M,et al.Changes in genetic selection differentials and generation intervals in US Holstein dairy cattle as a result of genomic selection[J].Proc Natl Acad Sci U S A,2016,113(28):E3995-E4004. |
[3] | VANDEHAAR M J,ARMENTANO L E,WEIGEL K,et al.Harnessing the genetics of the modern dairy cow to continue improvements in feed efficiency[J].J Dairy Sci,2016,99(6):4941-4954. |
[4] | BERRY D P,CROWLEY J J.CELL BIOLOGY SYMPOSIUM:genetics of feed efficiency in dairy and beef cattle[J].J Anim Sci,2013,91(4):1594-1613. |
[5] | HURLEY A M,LÓPEZ-VILLALOBOS N,MCPARLAND S,et al.Inter-relationships among alternative definitions of feed efficiency in grazing lactating dairy cows[J].J Dairy Sci,2016,99(1):468-479. |
[6] | KOCH R M,SWIGER L A,CHAMBERS D,et al.Efficiency of feed use in beef cattle[J].J Anim Sci,1963,22(2):486-494. |
[7] | DE ONDARZA M B,TRICARICO J M.Review:advantages and limitations of dairy efficiency measures and the effects of nutrition and feeding management interventions[J].Prof Anim Sci,2017,33(4):393-400. |
[8] | CONNOR E E.Invited review:improving feed efficiency in dairy production:challenges and possibilities[J]. Animal, 2015,9(3):395-408. |
[9] | BYSKOV M V,FOGH A,LØVENDAHL P.Genetic parameters of rumination time and feed efficiency traits in primiparous Holstein cows under research and commercial conditions[J].J Dairy Sci,2017,100(12):9635-9642. |
[10] | GONZALEZ-RECIO O,PRYCE J E,HAILE-MARIAM M,et al.Incorporating heifer feed efficiency in the Australian selection index using genomic selection[J].J Dairy Sci,2014,97(6):3883-3893. |
[11] | KÖNIG S,BOSSELMANN F,VON BORSTEL U U,et al.Genetic analysis of traits affecting the success of embryo transfer in dairy cattle[J].J Dairy Sci,2007,90(8):3945-3954. |
[12] | JATON C,KOECK A,SARGOLZAEI M,et al.Genetic analysis of superovulatory response of Holstein cows in Canada[J].J Dairy Sci,2016,99(5):3612-3623. |
[13] | GADDIS K L P,DIKMEN S,NULL D J,et al.Evaluation of genetic components in traits related to superovulation,in vitro fertilization,and embryo transfer in Holstein cattle[J].J Dairy Sci,2017,100(4):2877-2891. |
[14] | TAYLOR J F,SCHNABEL R D,SUTOVSKY P.Review:genomics of bull fertility[J].Animal,2018,12 Suppl 1:s172-s183. |
[15] | FORTES M R S,DEATLEY K L,LEHNERT S A,et al.Genomic regions associated with fertility traits in male and female cattle:advances from microsatellites to high-density chips and beyond[J].Anim Reprod Sci,2013, 141(1-2):1-19. |
[16] | BERRY D P,WALL E,PRYCE J E.Genetics and genomics of reproductive performance in dairy and beef cattle[J].Animal,2014,8 Suppl 1:105-121. |
[17] | HERD R M,ARTHUR P F,HEGARTY R S,et al.Potential to reduce greenhouse gas emissions from beef production by selection for reduced residual feed intake[C]//Proceedings of the 7th World Congress on Genetics Applied to Livestock Production.Montpellier,France,2002. |
[18] | DE HAAS Y,PSZCZOLA M,SOYEURT H,et al.Invited review:phenotypes to genetically reduce greenhouse gas emissions in dairying[J].J Dairy Sci,2017,100(2):855-870. |
[19] | DE HAAS Y,WINDIG J J,CALUS M P L,et al.Genetic parameters for predicted methane production and potential for reducing enteric emissions through genomic selection[J].J Dairy Sci,2011,94(12):6122-6134. |
[20] | BITTANTE G,CIPOLAT-GOTET C,CECCHINATO A.Genetic parameters of different FTIR-enabled phenotyping tools derived from milk fatty acid profile for reducing enteric methane emissions in dairy cattle[J]. Animals,2020,10(9):1654. |
[21] | LASSEN J,LØVENDAHL P.Heritability estimates for enteric methane emissions from Holstein cattle measured using noninvasive methods[J].J Dairy Sci,2016,99(3):1959-1967. |
[22] | RAVAGNOLO O,MISZTAL I.Genetic component of heat stress in dairy cattle,parameter estimation[J].J Dairy Sci,2000,83(9):2126-2130. |
[23] | RAVAGNOLO O,MISZTAL I,HOOGENBOOM G.Genetic component of heat stress in dairy cattle, development of heat index function[J].J Dairy Sci,2000,83(9):2120-2125. |
[24] | DIKMEN S,COLE J B,NULL D J,et al.Heritability of rectal temperature and genetic correlations with production and reproduction traits in dairy cattle[J].J Dairy Sci,2012,95(6):3401-3405. |
[25] | MALLARD B A,BURNSIDE E B,BURTON J H,et al.Variation in serum immunoglobulins in Canadian Holstein-Friesians[J].J Dairy Sci,1983,66(4):862-866. |
[26] | MAZENGERA K E,KENNEDY B W,BURNSIDE E B,et al.Genetic parameters of bovine serum immunoglobulins[J]. J Dairy Sci,1985,68(9):2309-2314. |
[27] | THOMPSON-CRISPI K A,SEWALEM A,MIGLIOR F,et al.Genetic parameters of adaptive immune response traits in Canadian Holsteins[J].J Dairy Sci,2012,95(1):401-409. |
[28] | DENHOLM S J,MCNEILLY T N,BANOS G,et al.Estimating genetic and phenotypic parameters of cellular immune-associated traits in dairy cows[J].J Dairy Sci,2017,100(4):2850-2862. |
[29] | 安涛,张海亮,王雅春.免疫大师公牛女儿的疾病抗性分析[J].中国畜牧兽医,2020,47(6):1791-1799.AN T,ZHANG H L,WANG Y C.Analysis on disease resistance of immunity+ bulls' daughters[J].China Animal Husbandry & Veterinary Medicine,2020,47(6):1791-1799.(in Chinese) |
[30] | WARNICK L D,JANSSEN D,GUARD C L,et al.The effect of lameness on milk production in dairy cows[J].J Dairy Sci,2001,84(9):1988-1997. |
[31] | BOOTH C J,WARNICK L D,GRÖHN Y T,et al.Effect of lameness on culling in dairy cows[J].J Dairy Sci,2004,87(12):4115-4122. |
[32] | VAN DER WAAIJ E H,HOLZHAUER M,ELLEN E,et al.Genetic parameters for claw disorders in Dutch dairy cattle and correlations with conformation traits[J].J Dairy Sci,2005,88(10):3672-3678. |
[33] | KOENIG S,SHARIFI A R,WENTROT H,et al.Genetic parameters of claw and foot disorders estimated with logistic models[J].J Dairy Sci,2005,88(9):3316-3325. |
[34] | VAN DER SPEK D,VAN ARENDONK J A M,VALLÉE A A A,et al.Genetic parameters for claw disorders and the effect of preselecting cows for trimming[J].J Dairy Sci,2013,96(9):6070-6078. |
[35] | MALCHIODI F,KOECK A,MASON S,et al.Genetic parameters for hoof health traits estimated with linear and threshold models using alternative cohorts[J].J Dairy Sci,2017,100(4):2828-2836. |
[36] | DE MOL R M,ANDRÉ G,BLEUMER E J B,et al.Applicability of day-to-day variation in behavior for the automated detection of lameness in dairy cows[J].J Dairy Sci,2013,96(6):3703-3712. |
[37] | KOECK A,MIGLIOR F,KELTON D F,et al.Short communication:genetic parameters for mastitis and its predictors in Canadian Holsteins[J].J Dairy Sci,2012,95(12):7363-7366. |
[38] | GADDIS K L P,VANRADEN P M,COLE J B,et al.Symposium review:development,implementation,and perspectives of health evaluations in the United States[J].J Dairy Sci,2020,103(6):5354-5365. |
[39] | ABDELSAYED M,HAILE-MARIAM M,PRYCE J E.Genetic parameters for health traits using data collected from genomic information nucleus herds[J].J Dairy Sci,2017,100(12):9643-9655. |
[40] | VUKASINOVIC N,BACCIU N,PRZYBYLA C A,et al.Development of genetic and genomic evaluation for wellness traits in US Holstein cows[J].J Dairy Sci,2017,100(1):428-438. |
[41] | ZWALD N R,WEIGEL K A,CHANG Y M,et al.Genetic selection for health traits using producer-recorded data.I.incidence rates,heritability estimates,and sire breeding values[J].J Dairy Sci,2004,87(12):4287-4294. |
[42] | GERNAND E,REHBEIN P,VON BORSTEL U U,et al.Incidences of and genetic parameters for mastitis,claw disorders,and common health traits recorded in dairy cattle contract herds[J].J Dairy Sci,2012,95(4):2144-2156. |
[43] | EGGER-DANNER C,COLE J B,PRYCE J E,et al.Invited review:overview of new traits and phenotyping strategies in dairy cattle with a focus on functional traits[J].Animal,2015,9(2):191-207. |
[44] | 张海亮,刘澳星,米思远,等.奶牛育种中的长寿性状[J].中国农业科学,2020,53(19):4070-4082.ZHANG H L,LIU A X,MI S Y,et al.A review on longevity trait in dairy cattle breeding[J].Scientia Agricultura Sinica,2020,53(19):4070-4082.(in Chinese) |
[45] | ZHANG H L,WANG Y C,CHANG Y,et al.Mortality-culling rates of dairy calves and replacement heifers and its risk factors in Holstein cattle[J].Animals,2019,9(10):730. |
[46] | PRITCHARD T,COFFEY M,MRODE R,et al.Understanding the genetics of survival in dairy cows[J].J Dairy Sci,2013,96(5):3296-3309. |
[47] | FORUTAN M,MAHYARI S A,SARGOLZAEI M.Genetic evaluation of calf and heifer survival in Iranian Holstein cattle using linear and threshold models[J].J Anim Breed Genet,2015,132(1):51-58. |
[48] | NORBERG E,PRYCE J E,PEDERSEN J.Short communication:a genetic study of mortality in Danish Jersey heifer calves[J].J Dairy Sci,2013,96(6):4026-4030. |
[49] | HANSEN M,MADSEN P,JENSEN J,et al.Genetic parameters of postnatal mortality in Danish Holstein calves[J].J Dairy Sci,2003,86(5):1807-1817. |
[50] | PENA D G,VUKASINOVIC N,BROOKER J,et al.Genomic predictions for calf wellness in Holstein cattle[J]. J Anim Sci,2018,96(S3):121. |
[51] | GONZALEZ-PENA D,VUKASINOVIC N,BROOKER J J,et al.Genomic evaluation for wellness traits in US Jersey cattle[J].J Dairy Sci,2020,103(2):1735-1748. |
[52] | 娄文琦,罗汉鹏,刘林,等.牛奶的中红外光谱相关指标及遗传规律研究进展[J].中国畜牧杂志, 2020,56(3):25-32.LOU W Q,LUO H P,LIU L et al.Advances in genetic aspects of mid-infrared spectrum related traits in cow milk[J].Chinese Journal of Animal Science,2020,56(3):25-32.(in Chinese) |
[53] | SOYEURT H,GILLON A,VANDERICK S,et al.Estimation of heritability and genetic correlations for the major fatty acids in bovine milk[J].J Dairy Sci,2007,90(9):4435-4442. |
[54] | FLEMING A,SCHENKEL F S,KOECK A,et al.Heritabilities of measured and mid-infrared predicted milk fat globule size,milk fat and protein percentages,and their genetic correlations[J].J Dairy Sci,2017,100(5):3735-3741. |
[55] | SOYEURT H,COLINET F G,ARNOULD V M R,et al.Genetic variability of lactoferrin content estimated by mid-infrared spectrometry in bovine milk[J].J Dairy Sci,2007,90(9):4443-4450. |
[56] | TOFFANIN V,PENASA M,MCPARLAND S,et al.Genetic parameters for milk mineral content and acidity predicted by mid-infrared spectroscopy in Holstein-Friesian cows[J].Animal,2015,9(5):775-780. |
[57] | FLEMING A,SCHENKEL F S,KOECK A,et al.Heritabilities of measured and mid-infrared predicted milk fat globule size,milk fat and protein percentages,and their genetic correlations[J].J Dairy Sci,2017,100(5):3735-3741. |
[58] | BASTIN C,GENGLER N,SOYEURT H.Phenotypic and genetic variability of production traits and milk fatty acid contents across days in milk for Walloon Holstein first-parity cows[J].J Dairy Sci,2011,94(8):4152-4163. |
[59] | SOYEURT H,DARDENNE P,DEHARENG F,et al.Genetic parameters of saturated and monounsaturated fatty acid content and the ratio of saturated to unsaturated fatty acids in bovine milk[J].J Dairy Sci,2008,91(9):3611-3626. |
[60] | VAN HULZEN K J E,SPRONG R C,VAN DER MEER R,et al.Genetic and nongenetic variation in concentration of selenium,calcium,potassium,zinc,magnesium,and phosphorus in milk of Dutch Holstein-Friesian cows[J].J Dairy Sci,2009,92(11):5754-5759. |
[61] | LINDSTRÖM U B,ANTILA V,SYVÄJÄRVI J.A note on some genetic and non-genetic factors affecting clotting time of Ayrshire milk[J].Acta Agric Scand,1984,34(3):349-355. |
[62] | BITTANTE G,PENASA M,CECCHINATO A.Invited review:genetics and modeling of milk coagulation properties[J].J Dairy Sci,2012,95(12):6843-6870. |
[63] | CECCHINATO A,DE MARCHI M,GALLO L,et al.Mid-infrared spectroscopy predictions as indicator traits in breeding programs for enhanced coagulation properties of milk[J].J Dairy Sci,2009,92(10):5304-5313. |
[64] | SUTHERLAND M A,ROGERS A R,VERKERK G A.The effect of temperament and responsiveness towards humans on the behavior,physiology and milk production of multi-parous dairy cows in a familiar and novel milking environment[J]. Physiol Behav,2012,107(3):329-337. |
[65] | VOISINET B D,GRANDIN T,TATUM J D,et al.Feedlot cattle with calm temperaments have higher average daily gains than cattle with excitable temperaments[J].J Anim Sci,1997,75(4):892-896. |
[66] | WAIBLINGER S,MENKE C,FÖLSCH D W.Influences on the avoidance and approach behaviour of dairy cows towards humans on 35 farms[J].Appl Anim Behav Sci,2003,84(1):23-39. |
[67] | 常瑶,朱莹琳,施佳庆,等.西荷杂交牛与荷斯坦牛重要经济性状对比[J].畜牧兽医学报,2018, 49(2):270-281.CHANG Y,ZHU Y L,SHI J Q,et al.A comparison study on economically important traits between Holstein and Simmental×Holstein crossbred cows[J].Acta Veterinaria et Zootechnica Sinica,2018,49(2):270-281.(in Chinese) |
[68] | STEPHANSEN R S, FOGH A, NORBERG E. Genetic parameters for handling and milking temperament in Danish first-parity Holstein cows[J]. J Dairy Sci, 2018, 101(12):11033-11039. |
[69] | GAULY M,MATHIAK H,ERHARDT G.Genetic background of behavioural and plasma cortisol response to repeated short-term separation and tethering of beef calves[J].J Anim Breed Genet,2002,119(6):379-384. |
[70] | BENHAJALI H,BOIVIN X,SAPA J,et al.Assessment of different on-farm measures of beef cattle temperament for use in genetic evaluation[J].J Anim Sci,2010,88(11):3529-3537. |
[71] | VISSCHER P M,GODDARD M E.Genetic parameters for milk yield,survival,workability,and type traits for Australian dairy cattle[J].J Dairy Sci,1995,78(1):205-220. |
[72] | LASSEN J,MARK T.Short communication:genotype by housing interaction for conformation and workability traits in Danish Holsteins[J].J Dairy Sci,2008,91(11):4424-4428. |
[73] | ADAMCZYK K,POKORSKA J,MAKULSKA J,et al.Genetic analysis and evaluation of behavioural traits in cattle[J].Livest Sci,2013,154(1-3):1-12. |
[74] | FRIEDRICH J,BRAND B,PONSUKSILI S,et al.Detection of genetic variants affecting cattle behaviour and their impact on milk production:a genome-wide association study[J].Anim Genet,2016,47(1):12-18. |
[75] | GUTIÉRREZ-GIL B,BALL N,BURTON D,et al.Identification of quantitative trait loci affecting cattle temperament[J].J Hered,2008,99(6):629-638. |
[76] | SCHMIDTZ B H,BUCHANAN F C,PLANTE Y,et al.Linkage mapping of the tyrosinase gene to bovine chromosome 29[J].Anim Genet,2001,32(2):119-120. |
[77] | HIENDLEDER S,THOMSEN H,REINSCH N,et al.Mapping of QTL for body conformation and behavior in cattle[J].J Hered,2003,94(6):496-506. |
[78] | SCHROOTEN C,BOVENHUIS H,COPPIETERS W,et al.Whole genome scan to detect quantitative trait loci for conformation and functional traits in dairy cattle[J].J Dairy Sci,2000,83(4):795-806. |
[79] | WIGGANS G R,THORNTON L L M,NEITZEL R R,et al.Short communication:genetic evaluation of milking speed for Brown Swiss dairy cattle in the United States[J].J Dairy Sci,2007,90(2):1021-1023. |
[80] | SEWALEM A,MIGLIOR F,KISTEMAKER G J.Analysis of the relationship between workability traits and functional longevity in Canadian dairy breeds[J].J Dairy Sci,2010,93(9):4359-4365. |
[81] | SEWALEM A,MIGLIOR F,KISTEMAKER G J.Short communication:genetic parameters of milking temperament and milking speed in Canadian Holsteins[J].J Dairy Sci,2011,94(1):512-516. |
[82] | MARETE A,SAHANA G,FRITZ S,et al.Genome-wide association study for milking speed in French Holstein cows[J].J Dairy Sci,2018,101(7):6205-6219. |
[83] | CHEN S Y,OLIVEIRA H R,SCHENKEL F S,et al.Using imputed whole-genome sequence variants to uncover candidate mutations and genes affecting milking speed and temperament in Holstein cattle[J].J Dairy Sci,2020,103(11):10383-10398. |
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