畜牧兽医学报 ›› 2020, Vol. 51 ›› Issue (12): 2954-2963.doi: 10.11843/j.issn.0366-6964.2020.12.005
吴富鑫1, 熊本海2, 童津津1*, 蒋林树1*
收稿日期:
2020-06-29
出版日期:
2020-12-25
发布日期:
2020-12-23
通讯作者:
童津津,主要从事奶牛营养与免疫研究,E-mail:tongjinjin0451@163.com;蒋林树,主要从事奶牛营养与免疫研究,E-mail:kjxnb@vip.sina.com
作者简介:
吴富鑫(1995-),男,山东济宁人,硕士生,主要从事奶牛营养与免疫研究,E-mail:2996440432@qq.com
基金资助:
WU Fuxin1, XIONG Benhai2, TONG Jinjin1*, JIANG Linshu1*
Received:
2020-06-29
Online:
2020-12-25
Published:
2020-12-23
摘要: 链球菌、金黄色葡萄球菌和大肠杆菌是引起奶牛乳腺炎的3大病原菌,在链球菌属中无乳链球菌是引起奶牛乳腺炎的重要病原菌之一,由无乳链球菌导致的乳腺炎约占隐性乳腺炎发病率的56.25%。无乳链球菌入侵奶牛乳腺的过程主要包括感染、黏附上皮细胞、侵入上皮细胞、损伤机体和免疫逃避等过程。无乳链球菌的毒力因子具有附着和侵袭机体细胞的作用,使菌体在奶牛乳腺表面形成生物被膜,进而干扰机体的正常免疫功能并引起疾病。本文主要阐述了无乳链球菌在入侵乳腺组织过程中发挥主要作用的毒力因子的种类、作用机制以及调控过程,旨在通过抑制其相关毒力因子的活性,从而阻断无乳链球菌在乳腺中感染和传播,进而为预防和治疗链球菌型乳腺炎提供新的思路。
中图分类号:
吴富鑫, 熊本海, 童津津, 蒋林树. 奶牛乳腺炎无乳链球菌毒力相关因子[J]. 畜牧兽医学报, 2020, 51(12): 2954-2963.
WU Fuxin, XIONG Benhai, TONG Jinjin, JIANG Linshu. Advances on Virulence Factors of Streptococcus agalactiae of Dairy Cows Mastitis[J]. Acta Veterinaria et Zootechnica Sinica, 2020, 51(12): 2954-2963.
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