牛胚胎干细胞研究进展

doi:10.11843/j.issn.0366-6964.2014.11.001

Abstract

Abstract:

The study of bovine embryonic stem (ES) cells have shown that they have potential application in livestock industry.For instance，bovine ES cells could be used to study bovine early embryo development and would contribute to new varieties of bovine breed.Although it has been reported that many bovine embryonic stem cell-like cell lines have been got both in China and abroad，no validated bovine ES cell lines has been generated up to now.Researchers have achieved great progress in the study of mouse and human ES cells in recent years，and the culture conditions of the ES cells are relatively mature.But when used the same culture condition in bovine ES cells，the result is not so good.The generation of bovine ES cell lines could be affected by many factors，such as cytokines，pluripotent genes and surface markers，passage methods and feeder cells.This paper aims to summarize the current research progress of bovine ES cells at home and abroad，analyze some important factors affecting the generation of bovine ES cell lines and discuss its developing trends.

Key words: bovine, embryonic stem cells, factors, developing trends

CLC Number:

S823.2

CUI Li-sha,ZHAO Xue-ming，HAO Hai-sheng，DU Wei-hua,ZHU Hua-bin . The Research Progress of Bovine Embryonic Stem Cells[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2014, 45(11): 1739-1745.

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The Research Progress of Bovine Embryonic Stem Cells

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