寿光鸡GPR147基因5′调控区多态性与产蛋性状的关联分析

doi:10.11843/j.issn.0366-6964.2016.01.005

Abstract

Abstract:

To investigate the single nucleotide polymorphisms (SNPs) of GPR147 gene and the correlations between SNPs and laying traits，the SNPs in the 5′ regulatory region of GPR147 of Shouguang chicken were detected by direct sequencing method and their associations with laying traits of Shouguang chickens were analyzed.The results showed that there were 11 SNPs loci in the 5′ regulatory region of GPR147 gene detected in the population.The －593 and －579 loci had significant effects on egg production from 45- to 56-week-old and total egg number until 56-week-old (P<0.05).Genotype TT at the －593 locus and AA at －579 locus were associated with higher egg production.Haplotype analysis of the 2 loci showed that hens with haplotype TA laid 1.5，2.5，1.6 and 4.4 eggs more than that with haplotype CG during 26-44 weeks of age (P=0.041 8)，45-56 weeks of age (P=0.032 6)，the period until 300 days of age (P=0.1) and the total period until 56 weeks of age (P=0.014 4)，respectively.In summary，the 5′ regulatory region of the GPR147 has highly polymorphic，SNPs and haplotypes at －593 and －579 loci have significant impacts on the egg number of Shouguang chickens，and they can be used as potential and valuable candidate molecular markers.

CLC Number:

S813.2

JIA Mei-ting，LI Xian-yao，KANG Li，JIANG Yun-liang，FAN Xin-zhong，TANG Hui. Association of Polymorphisms in the 5′ Regulatory Region of GPR147 with Laying Performance in Shouguang Chickens[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2016, 47(1): 34-40.

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Association of Polymorphisms in the 5′ Regulatory Region of GPR147 with Laying Performance in Shouguang Chickens

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