牛支原体逃避宿主免疫的研究进展

doi:10.11843/j.issn.0366-6964.2017.03.002

Abstract

Abstract:

Mycoplasma bovis is considered to be one of the important pathogenic agents of cattle. It can persist in the host and causes a series of chronic diseases including bronchopneumonia, mastitis, otitis, genital disorders, arthritis, meningitis or keratoconjunctivitis. Due to the resistance to antibotic therapy and the lake of commercially available diagnostic tools and effective vaccines, M. bovis-induced diseases are difficult to prevent and control. The main reason of persisitent infection caused by M. bovis is to evade the host innate and adaptive immunity through high frequent variation of membrane surface antigens, avoiding phagocytosis, cell invasion, biofilm formation and modulating host immune responses. Deeply understanding immune evasion mechanism of M. bovis is helpful to develop the new dignostic tools and novel vaccines, and it is also beneficial to prevent and control the diseases.

CLC Number:

S852.62

JI Wen-heng, CHU Yue-feng, ZHAO Ping, CHEN Sheng-li, HAO Hua-fang,WANG Zhan-hui，LIU Yong-sheng. Advances in the Research of Immune Evasion by Mycoplasma bovis[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2017, 48(3): 393-402.

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Advances in the Research of Immune Evasion by Mycoplasma bovis

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