黄芪、枸杞、金银花等中草药复方制剂对肉鸡免疫器官发育及免疫功能的影响

doi:10.11843/j.issn.0366-6964.2017.06.018

Abstract

Abstract:

To study the effect of compound Chinese herbal composed of Astragalus, Chinese wolfberry, honeysuckle and other herbs on immune organ development and immune function of broilers. A total of 1 000 one-day-old Avian broilers (AA broilers) were randomly divided into control group and experimental groupsⅠ, Ⅱ and Ⅲ, each group included 5 pens (50 birds per pen). Control group was fed with the basal diet and experimental groupsⅠ, Ⅱ and Ⅲ were fed with the basal diet supplemented with 0.5%, 1.0% and 1.5% compound Chinese herbal for 42 days, respectively. Results showed: compared with control group, the index of bursa of Fabricius, serum IgG and IgM concentration, serum NDV antibody and IL-4 levels were significantly increased in experimental group Ⅱ(P<0.05); the weight and organ index of thymus, the levels of serum IL-2 and IFN-γ were significantly increased in experimental group Ⅲ(P<0.05); the serum IgG concentration and NDV antibody level were significantly increased in experimental groupⅠof broilers (P<0.05). At 42 days of age, the weight and organ index of thymus and bursa, the serum IgG and IgM concentration, the serum NDV antibody and IL-4 levels were significantly increased in experimental groupⅡ (P<0.05); the weight and organ index of spleen, the levels of serum IL-2,IL-4 and IFN-γ were significantly increased in experimental group Ⅲ(P<0.05); the serum IgG and IgM concentration, the serum NDV antibody level were significantly increased in experimental groupⅠcompared with control group of broilers (P<0.05). Microscopic observation has also showed: At 21 days of age, the structure of bursa of Fabricius was clear, the area of bursa of Fabricius node was obviously increased (P<0.05), in which the numbers of lymphocytes were also increased and tight arranged in experimental group Ⅱ of broilers. At 42 days of age, the thymic cortex were thicker (P<0.05), and the area of bursa of Fabricius node was obviously increased in experimental group Ⅱ of broilers (P<0.05); the thymic cortex were also thicker (P<0.05), the area of peripheral lymphatic sheath and spleen node were significantly increased (P<0.05), and the number of spleen node were increased in experimental group Ⅲ of broilers; the area of spleen node in the experiment group Ⅰ was significantly higher than that of the control group (P<0.05). The results have indicated that supplementation of different doses of compound Chinese herbal medicine preparation of Astragalus wolfberry and honeysuckle can improve immune organ development and immune function of broilers to some extent, in which supplementation of 1.0% compound Chinese herbal preparation have the best effect.

CLC Number:

S853.7

JIN Er-hui, CHEN Yao-xing, ZHOU Jin-xing, LI Sheng-he, REN Man, HU Qian-qian, JIN Guang-ming. The Effect of Compound Chinese Herbal Medicine Preparation of Astragalus, Wolfberry and Honeysuckle Flower on Immune Organ Development and Immune Functions of Broiler[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2017, 48(6): 1128-1139.

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The Effect of Compound Chinese Herbal Medicine Preparation of Astragalus, Wolfberry and Honeysuckle Flower on Immune Organ Development and Immune Functions of Broiler

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