猪繁殖与呼吸综合征病毒致病机理及其抗病育种研究进展

doi:10.11843/j.issn.0366-6964.2013.11.001

Abstract

Abstract:

Porcine reproductive and respiratory syndrome （PRRS），caused by porcine reproductive and respiratory syndrome virus （PRRSV），is a major infectious disease leading to the most economically loss in swine industry. Research shows that PRRSV virion invade host cells via three entry mediators (HS,Sn,CD163). PRRSV can inhibit host immune response by inhibiting innate immunity and delaying neutralizing antibody, resulting in persistent infection.Resistance breeding can improve natural immunity, mainly by means of direct selection, indirect selection and transgene. In this paper, the research status of PRRSV pathogenesis and resistance breeding has been reviewed, and the development of novel resistance approaches to PRRSV are also proposed.

CLC Number:

S813.2

CHEN Jing-yao, LIU Xiao-juan, WANG Yu-hang, LI Li, HU Xiao-xiang, LI Ning. Advances in Pathogenesis and Resistance Breeding of Porcine Reproductive and Respiratory Syndrome Virus[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2013, 44(11): 1693-1699.

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Advances in Pathogenesis and Resistance Breeding of Porcine Reproductive and Respiratory Syndrome Virus

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