犬多层螺旋CT肝多期增强扫描技术研究

doi:10.11843/j.issn.0366-6964.2022.10.037

Abstract

Abstract: The aim of this research was to determine the dose and injection rate of contrast medium and the optimal delay time for multi-phase contrast-enhanced scanning of liver in dogs. Different iohexol doses (500, 575 and 650 mg·kg^-1, calculated based on I content) and injection rates (2 and 3 mL·s^-1) were selected for dynamic scanning modality in dog. The CT enhancement values of aorta, portal vein and liver parenchyma were respectively calculated to determine the optimal dose and injection rate of contrast medium. Then the dogs of different sizes were scanned using the optimal contrast medium dose and injection rate. The time-density curves of aorta, portal vein and liver parenchyma were drawn after dynamic scanning. The peak arrival times of aorta, portal vein and liver parenchyma were counted, and the difference between the peak arrival time and injection time (Δt_AO/Δt_SP/Δt_L) were calculated to determine the optimal scanning delay time of each phase. The results showed that the CT enhancement values of aorta, portal vein and liver parenchyma were higher with a dose of 575 mg·kg^-1 at an injection rate of 3 mL·s^-1. Perfect contrast enhancement effect could be obtained in these situations. The Δt_AO values of small, medium and large size dogs were 7, 9 and 4 s, Δt_SP were 21, 23 and 17 s, and Δt_L were 41, 44 and 34 s, according to the time density curves. The optimal scan delay times in each phase could be calculated by the equation "injection time+Δt_ROI-1/2 scan time". It has been verified in clinical cases that the dose of contrast medium (I, 575 mg·kg^-1), injection rate (3 mL·s^-1) and delay times ("injection time +Δt_AO/Δt_SP/Δt_L-1/2 scan time") used in this research had better clinical contrast enhancement effects on liver image and can be applied to contrast-enhancement CT diagnosis of liver diseases in dogs.

Key words: dogs, liver, CT, multiphasic enhancement, iohexol, injection rate, delay time

CLC Number:

S854.7

LIAO Yun,GUO Yiwen,LI Lingxu,SU Zenan,JIANG Huaide,YANG Deji,ZHAO Yanbing,YAO Dawei. Multiphasic Contrast-enhanced Multi-slice Spiral CT Scanning Technology of Liver in Dogs[J]. Acta Veterinaria et Zootechnica Sinica, 2022, 53(10): 3667-3674.

References 20

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Multiphasic Contrast-enhanced Multi-slice Spiral CT Scanning Technology of Liver in Dogs

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