ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2016, Vol. 47 ›› Issue (2): 213-217.doi: 10.11843/j.issn.0366-6964.2016.02.001

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Progresses in Research of Genome-wide Association Study Methods

HAO Xing-jie,HU Lin,ZHANG Shu-jun*   

  1. (Key Laboratory of Animal Breeding and Reproduction of Ministry of Education,College of Animal Science and Technology/College of Veterinary Medicine,Huazhong Agricultural University,Wuhan 430070,China)
  • Received:2015-06-01 Online:2016-02-23 Published:2016-02-23

Abstract:

The genome-wide association study (GWAS) has become an effective approach to identify genetic variants associated with complex traits and diseases.However,population structure can result in spurious association.In the past few decades,new approaches were developed and improved to minimize the influence of population structure.In this review,we summarize some new approaches to treat population structure for selecting the best method for any GWAS to reveal the genetic backgroud of some traits.

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