顶复门原虫DNA/RNA甲基化及与赖氨酸乙酰化修饰的关系

doi:10.11843/j.issn.0366-6964.2025.12.012

摘要/Abstract

摘要：

DNA/RNA甲基化和赖氨酸乙酰化修饰同为重要的表观遗传修饰，在调控基因表达和蛋白活力等生命过程中起重要作用，也是极具应用前景的药物作用靶标。本文将主要对DNA/RNA甲基化修饰和组蛋白乙酰化修饰调控顶复门原虫发育转化的研究进展进行综述，以期为新型抗顶复门原虫药物靶标筛选提供依据。

关键词: 顶复门原虫, DNA/RNA甲基化, 赖氨酸乙酰化修饰

Abstract:

DNA/RNA methylation and lysine acetylation modifications are both important epigenetic modifications that play a crucial role in regulating gene expression and protein activity in life processes. DNA/RNA methylation and lysine acetylation modification are also highly promising drug targets. This article will mainly review the research progress on DNA/RNA methylation modification and histone acetylation modification in regulating the development and transformation of Apicomplexan parasites, in order to provide a basis for the screening of new anti-coccidial drug targets.

Key words: Apicomplexan parasites, DNA/RNA methylation, lysine acetylation modification

中图分类号:

R382
S852.72

曹尚, 龚振兴. 顶复门原虫DNA/RNA甲基化及与赖氨酸乙酰化修饰的关系[J]. 畜牧兽医学报, 2025, 56(12): 6073-6079.

CAO Shang, GONG Zhenxing. The Relationship between DNA/RNA Methylation and Lysine Acetylation Modification of Apicomplexan Parasites[J]. Acta Veterinaria et Zootechnica Sinica, 2025, 56(12): 6073-6079.

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