山羊瘤胃的三维重建及有限元分析

doi:10.11843/j.issn.0366-6964.2019.12.021

摘要/Abstract

摘要： 作者基于山羊瘤胃CT图像对湘东黑山羊瘤胃进行三维重建及有限元模型仿真分析，拟建立山羊瘤胃的几何模型和有限元模型。首先利用三维重建软件Mimics重建山羊瘤胃几何模型，再利用Solidworks把几何模型的格式转换为IGES格式导入到有限元分析软件Hyperworks中形成有限元网格模型，最后通过Hyperworks、Ls_dyna联合仿真，对体外重构的瘤胃有限元模型进行力学性能分析。结果表明，体外重构的瘤胃模型与活体动物瘤胃有高度的几何相似性，能够清楚地展现出瘤胃的囊腔结构；并且获得对瘤胃模型进行力学分析后的应力、应变和位移云图；建立可视化瘤胃的几何模型和有限元模型；描绘出瘤胃在自然状态下的外形结构以及生物力学特性。本研究验证了三维重建及有限元法在山羊瘤胃建模中的可行性，同时也为瘤胃重构方面的研究开辟了先河，在动物组织模型构建上开辟了新的途径。

关键词: 黑山羊, 瘤胃模型, 三维重建, 有限元分析

Abstract: This study was carried out to establish geometric model and finite element model of goat rumen, three dimensional reconstruction and finite element simulation model were used based on CT images of rumen of Xiangdong black goats. Firstly, the three dimensional reconstruction software (Mimics) was used to reconstruct the geometric model of rumen, and then Solidworks was used to convert the geometric model into IGES format and import it into the finite element mesh model in the finite element analysis software Hyperworks. Finally, Hyperworks and Ls_dyna combined simulation were used to analyze the mechanical properties of the in vitro reconstructed finite element model of rumen. The results indicated that in vitro reconstructed rumen model was similar to the rumen of living animals geometrically, and this model can clearly reflect the lumen structure of the rumen. After the mechanical analysis of the rumen model, the stress, strain and displacement nephograms of the rumen model were obtained. Geometric model and finite element model of visual rumen were established to reflect the appearance structure and biomechanical characteristics of rumen in natural state. These results indicated that the feasibility of three dimensional reconstruction and finite element method in goat rumen modeling were also verified, which built up a new method for rumen reconstruction and construction researching.

Key words: black goats, rumen model, three dimensional reconstruction, finite element analysis

中图分类号:

宋阳, 沈维军, 仇慧静, 朱媚, 陈东, 张佩华. 山羊瘤胃的三维重建及有限元分析[J]. 畜牧兽医学报, 2019, 50(12): 2560-2570.

SONG Yang, SHEN Weijun, QIU Huijing, ZHU Mei, CHEN Dong, ZHANG Peihua. Three Dimensional Reconstruction and Finite Element Model Analysis of Goat Rumen[J]. Acta Veterinaria et Zootechnica Sinica, 2019, 50(12): 2560-2570.

参考文献 32

[1]	张晋,孙良璋. 三维重建技术在肺肿瘤临床教学中的应用探讨[J]. 中国继续医学教育, 2017, 9(26):34-35.ZHANG J, SUN L Z. The application of three-dimensional reconstruction in lung tumor clinical teaching[J]. China Continuing Medical Education, 2017, 9(26):34-35. (in Chinese)
[2]	杨俊武. 三维重建虚拟肝切除在肝癌切除术中的应用研究[D]. 南昌:南昌大学, 2017.YANG J W. The application of virtual liver resection based on three-dimensional reconstruction in hepatectomy for hepatocellular carcinoma[D]. Nanchang:Nanchang University, 2017. (in Chinese)
[3]	赵鹏翔, 杨雨霏,张东杰,等. 三维重建技术在肝癌治疗中的应用研究进展[J]. 中国现代普通外科进展, 2018, 21(9):706-710, 728.ZHAO P X, YANG Y F, ZHANG D J, et al. Application and research progress of three-dimensional reconstruction technology in the treatment of liver cancer[J]. Chinese Journal of Current Advances in General Surgery, 2018, 21(9):706-710, 728. (in Chinese)
[4]	马晓超, 王盈舒,王瑞,等. 三维重建技术在食管癌术前诊断的临床应用价值[J]. 中国实验诊断学, 2019, 23(2):203-206.MA X C, WANG Y S, WANG R, et al. Role of 3D reconstruction in the evaluation of patients with lower segment oesophageal cancer[J]. Chinese Journal of Laboratory Diagnosis, 2019, 23(2):203-206. (in Chinese)
[5]	陈静. 厚壁性肝外胆管癌和肝外胆管炎的能谱CT鉴别诊断及可视化三维重建[D]. 福州:福建医科大学, 2017.CHEN J. Differential diagnosis by CT spectral imaging for thickness extrahepatic cholangiocarcinoma and extrahepatic cholangitis and 3D reconstruction visualization[D]. Fuzhou:Fujian Medical University, 2017. (in Chinese)
[6]	高伟,杨昱童,张诗瑶,等. 猫视乳头三维模型重建及有限元分析[J]. 中国组织工程研究, 2016, 20(18):2717-2724.GAO W, YANG Y T, ZHANG S Y, et al. Three-dimensional reconstruction and finite element analysis of the optic nerve head of a cat[J]. Chinese Journal of Tissue Engineering Research, 2016, 20(18):2717-2724. (in Chinese)
[7]	李艳娜, 居来提·买提肉孜,尼加提·外力,等. 基于三维有限元建模方法分析维医沙疗对兔股骨力学性能的影响[J]. 中国组织工程研究, 2016, 20(27):3957-3962.LI Y N, MAITIROUZI J, WAILI N, et al. Influence of sand therapy in Uyghur medicine on mechanical properties of rabbits' femur based on three-dimensional finite element modeling[J]. Chinese Journal of Tissue Engineering Research, 2016, 20(27):3957-3962. (in Chinese)
[8]	王敬夫, 贾骏麒,田磊,等. 猪颌面软硬复合组织破片伤有限元模型的建立与与有效性分析[J]. 实用口腔医学杂志, 2018, 34(1):16-20.WANG J F, JIA J Q, TIAN L, et al. Development and validation of a FE model in swine mandibular composite tissue of fragment injury[J]. Journal of Practical Stomatology, 2018, 34(1):16-20. (in Chinese)
[9]	邓健全, 黄海龙,陈小宇. 小型猪冠状动脉的三维建模与3D打印研究[J]. 局解手术学杂志, 2018, 27(12):849-853.DENG J Q, HUANG H L, CHEN X Y. Three dimensional modeling and 3D printing of coronary artery in miniature pigs[J]. Journal of Regional Anatomy and Operative Surgery, 2018, 27(12):849-853. (in Chinese)
[10]	邓健全, 黄海龙. 小型猪肾脏血管的三维可视化建模及意义[J]. 中国比较医学杂志, 2018, 28(12):27-31.DENG J Q, HUANG H L. To establish a three dimensional visualization model of miniature pig renal vasculature and its significance[J]. Chinese Journal of Comparative Medicine, 2018, 28(12):27-31. (in Chinese)
[11]	RANZONI A M, CORCELLI M, ARNETT T R, et al. Micro-computed tomography reconstructions of tibiae of stem cell transplanted osteogenesis imperfecta mice[J]. Sci Data, 2018, 5:180100.
[12]	KUYINU E L, NARAYANAN G, NAIR L S, et al. Animal models of osteoarthritis:classification, update, and measurement of outcomes[J]. J Orthop Surg Res, 2016, 11:19.
[13]	ZHOU X M, TIAN Q H, DU Y X, et al. The finite element analysis of machine tool column of NC gear shaper based on HyperWorks[J]. Appl Mech Mater, 2012, 229-231:491-494.
[14]	CAO F Y, LI J L, CUI M K. Analysis of frame structure of medium and small truck crane[C]//Proceedings of the 2nd International Workshop on Advances in Energy Science and Environment Engineering. Zhuhai:AESEE, 2018.
[15]	XIANG Y, LI J T, TIAN Z Z. The finite element analysis and optimization of the hood based on hyperworks[J]. Appl Mech Mater, 2015, 733:548-553.
[16]	SHI P C, XU Z W. Analysis of seat belt anchorage strength for vehicles[J]. IOP Conf Ser Mater Sci Eng, 2018, 301(1):012127.
[17]	FU W W, ZHANG X G, WANG J Q, et al. Simulation study on gender differences in occupant dynamic response during spacecraft landing impact[J]. Int J Crashworthiness, 2017, 22(5):582-588.
[18]	WANG W W, YANG S, LIN C. Clay-like mechanical properties for the jellyroll of cylindrical Lithium-ion cells[J]. Appl Energy, 2017, 196:249-258.
[19]	STANCIU M D, ARDELEANU A F, DRÃGHICESCU H T. Reverse engineering in finite element analysis of the behaviour of lignocellulosic materials subjected to cyclic stresses[J]. Proced Manuf, 2018, 22:65-72.
[20]	柯显信, 尚宇峰,卢孔笔. 基于HyperWorks仿人机器人面部表情仿真[J]. 制造业自动化, 2015, 37(1):118-121, 137.KE X X, SHANG Y F, LU K B. Simulation of humanoid robot facial expression based on HyperWorks[J]. Manufacturing Automation, 2015, 37(1):118-121, 137. (in Chinese)
[21]	朱海燕. 基于ANSYS/LS-DYNA的生物瓣膜动态力学性能分析[D]. 济南:山东大学, 2011.ZHU H Y. Dynamic mechanical analysis of the bioprosthetic heart valve based on ANSYS/LS-DYNA[D]. Ji'nan:Shandong University, 2011. (in Chinese)
[22]	LIM Y J, DEO D, SINGH T P, et al. In situ measurement and modeling of biomechanical response of human cadaveric soft tissues for physics-based surgical simulation[J]. Surg Endosc, 2009, 23(6):1298-1307.
[23]	YEH W C, LI P C, JENG Y M, et al. Elastic modulus measurements of human liver and correlation with pathology[J]. Ultrasound Med Biol, 2002, 28(4):467-474.
[24]	梁英宗. 数字肝脏三维重建技术的研究[D]. 重庆:重庆大学, 2013.LIANG Y Z. Research on 3D reconstruction technologies of liver[D]. Chongqing:Chongqing University, 2013. (in Chinese)
[25]	李悦溪. 人体胃部三维有限元模型的建立[D]. 杭州:浙江大学, 2007.LI Y X. Research on the method for 3D finite element modeling of human stomach[D]. Hangzhou:Zhejiang University, 2007. (in Chinese)
[26]	LEEMANN A, LURA P. E-modulus of the alkali-silica-reaction product determined by micro-indentation[J]. Constr Build Mater, 2013, 44:221-227.
[27]	BROWN R E. Digestive physiology and nutrition of ruminants[J]. J Dairy Sci, 1970, 53(9):1304.
[28]	SHIN D S, LEE S, PARK H S, et al. Segmentation and surface reconstruction of a cadaver heart on Mimics software[J]. Folia Morphol, 2015, 74(3):372-377.
[29]	赵晓磊, 郭春超,齐秋菊,等. 基于Mimics软件的人体肾脏三维模型重建方法[J]. 计算机光盘软件与应用, 2014(20):65, 67.ZHAO X L, GUO C C, QI Q J, et al. 3D model reconstruction of human kidney based on Mimics[J]. Computer CD Software and Applications, 2014(20):65, 67. (in Chinese)
[30]	GUO H C, WANG Y, DAI J, et al. Application of 3D printing in the surgical planning of hypertrophic obstructive cardiomyopathy and physician-patient communication:a preliminary study[J]. J Thorac Dis, 2018, 10(2):867-873.
[31]	MAZZOLI A, ANTONIO G, MASI A, et al. Use of MIMICS® software in three-dimensional cephalometric evaluation of soft tissues of the face[J]. Comput Methods Biomech Biomed Eng Imaging Vis, 2017, 5(1):3-15.
[32]	刘敏雄. 反刍动物消化生理学[M]. 北京:北京农业大学出版社, 1991:18-24.LIU M X. Physiology of ruminant digestion[M]. Beijing:Beijing Agricultural University Press, 1991:18-24. (in Chinese)